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http://dx.doi.org/10.3795/KSME-A.2005.29.6.787

An Evaluation of Low Intensity Ultrasonic Characteristics for Arthritis Healing  

Hong Sung-Min (경희대학교 동서의학대학원 의료공학)
Han Seung-Moo (경희대학교 동서의학대학원 의료공학)
Publication Information
Transactions of the Korean Society of Mechanical Engineers A / v.29, no.6, 2005 , pp. 787-794 More about this Journal
Abstract
Nowadays chronic degenerative diseases such as arthritis are increasing rapidly, even though acute infectious diseases are decreasing due to the advance of modern medicine. Although many of remedies are developed for arthritis healing, there is no precise medical prescription, and pathogenesis is not examined exactly. In this study, we confirmed gene expression of BMP 1A, BMP 2B, osteonectin and MGP which are genes related with bone formation in osteoblast by using ultrasonic stimulation. Through this study, we also evaluated the fact that ultrasound could be applied to arthritis healing by making activated osteoblast induce remodeling of cartilage. As a result of this research, BMP 2B and MGP have higher rates of expression in specific ultrasound mode. In conclusion, it is expected that ultrasound could be used efficiently for healing arthritis if we use ultrasounds according to symptoms of arthritis on reasonable terms.
Keywords
Ultrasound; Osteoblast; Arthritis;
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