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http://dx.doi.org/10.22643/JRMP.2022.8.1.33

Recent advances in [18F]F-DPA as a promising translocator protein ligand for PET study  

Hee-Kwon Kim (Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Jeonbuk National University Medical School and Hospital)
Publication Information
Journal of Radiopharmaceuticals and Molecular Probes / v.8, no.1, 2022 , pp. 33-37 More about this Journal
Abstract
Translocator protein (TSPO) is associated with neurodegeneration diseases, and the development of potent ligands with high affinity to TSPO was valuable study for many scientists. Specially, pyrazolo[1,5-a]pyrimidine moiety has been employed for development of new TSPO ligands with good properties. In this highlight review, the development of [18F]F-DPA as a promising TSPO ligand as PET tracer is described.
Keywords
$[^{18}F]F-DPA$; Translocator protein; Positron emission tomography (PET); Pyrazolo[1,5-a]pyrimidine; PET tracer;
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