1 |
Ayed T, Pilme J, Teze D, Bassal F, Barbet J, Cherel M, Champion J, Maurice R, Montavon G, Galland N. -labeled agents for alpha-immunotherapy: On the in vivo stability of astatine-agent bonds. Eur J Med Chem 2016;116:156-164.
DOI
|
2 |
Wilbur DS. Chemical and Radiochemical Considerations in Radiolabeling with -Emitting Radionuclides. Curr Radiopharm 2011;4:214-247.
DOI
|
3 |
Akabani G, Carlin S, Welsh P, Zalutsky MR. In vitro cytotoxicity of -labeled trastuzumab in human breast cancer cell lines: Effect of specific activity and HER2 receptor heterogeneity. Nucl Med Biol 2006;33:333-347.
DOI
|
4 |
Green DJ, Shadman M, Jones JC, Frayo SL, Kenoyer AL, Hylarides MD, Hamlin DK, Wilbur DS, Balkan ER, Lin Y, Miller BW, Frost SH, Gopal AK, Orozco JJ, Gooley TA, Laird KL, Till BG, Back T, Sandmaier BM, Pagel JM, Press OW. Astatine-211 conjugated to an anti-CD20 monoclonal antibody eradicates disseminated B-cell lymphoma in a mouse model. Blood 2015;125:2111-2119.
DOI
|
5 |
Vaidyanathan G, Zalutsky MR. 1-(m-[ ]astatobenzyl) guanidine: Synthesis via astato demetalation and preliminary in vitro and in vivo evaluation. Bioconjug Chem 1992;3:499-503.
DOI
|
6 |
Cederkrantz E, Andersson H, Bernhardt P, Back T, Hultborn R, Jacobsson L, Jensen H, Lindegren S, Ljungberg M, Magnander T, Palm S, Albertsson P. Absorbed Doses and Risk Estimates of -MX35 F(ab')2 in Intraperitoneal Therapy of Ovarian Cancer Patients. Int J Radiat Oncol Biol Phys 2015;93:569-576.
DOI
|
7 |
Orozco JJ, Back T, Kenoyer A, Balkin ER, Hamlin DK, Wilbur DS, Fisher DR, Frayo SL, Hylarides MD, Green DJ, Gopal AK, Press OW, Pagel JM. Anti-CD45 radioimmunotherapy using with bone marrow transplantation prolongs survival in a disseminated murine leukemia model. Blood 2013;121:3759-3767.
DOI
|
8 |
Li Y, Hamlin DK, Chyan MK, Wong R, Dorman EF, Emery RC, Woodle DR, Manger RL, Nartea M, Kenoyer AL, Orozco JJ, Green DJ, Press OW, Storb R, Sandmaier BM, Wilbur DS. cGMP production of astatine-211-labeled anti-CD45 antibodies for use in allogeneic hematopoietic cell transplantation for treatment of advanced hematopoietic malignancies. PLoS One 2018;13:e0205135
DOI
|
9 |
Vaidyanathan G, Friedman HS, Keir ST, Zalutsky MR. Evaluation of meta-[ ]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model. Nucl Med Biol 1996;23:851-856.
DOI
|
10 |
Vaidyanathan G, Affleck, DJ, Alston KL, Zhao XG, Hens M, Hunter DH, Babich J, Zalutsky MR. A kit method for the high level synthesis of [ ]MABG. Bioorg Med Chem 2007;15:3430-3436.
DOI
|
11 |
Choi J, Vaidyanathan G, Koumarianou, Kang CM, Zalutsky MR. Astatine-211 labeled anti-HER2 5F7 single domain antibody fragment conjugates: radiolabeling and preliminary evaluation. Nucl Med Biol 2017;56:10-20.
|
12 |
Rowe SP, Drzezga A, Neumaier B, Dietlein M, Gorin MA, Zalutsky MR, Pomper MG. Prostate-Specific Membrane Antigen-Targeted Radiohalogenated PET and Therapeutic Agents for Prostate Cancer. J Nucl Med 2016;57:90S-96S.
DOI
|
13 |
Kiess AP, Minn I, Vaidyanathan G, Hobbs RF, Josefsson A, Shen C, Brummet M, Chen Y, Choi J, Koumarianou E, Baidoo K, Brechbiel MW, Mease RC, Sgouros G, Zalutsky MR, Pomper MG. (2S)-2-(3-(1-Carboxy-5-(4- -Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted -Particle Radiopharmaceutical Therapy. J Nucl Med 2016;57:1569-1575.
DOI
|
14 |
Dmitriev OY, Lutsenko S, Muyldermans S. Nanobodies as Probes for Protein Dynamics in Vitro and in Cells. J Biol Chem 2016;291:3767-3775.
DOI
|
15 |
Kim G, Chun K, Park SH, Kim B. Production of alpha-particle emitting using 45 MeV alpha-beam. Phys Med Biol 2014;59:2849-2860.
DOI
|
16 |
Crawford JR, Yang H, Kunz P, Wilbur DS, Schaffer P, Ruth TJ. Development of a preclinical generator system for targeted alpha therapy research with . Nucl Med Biol 2017;48:31-35.
DOI
|
17 |
Kang HJ, Lee SS, Byun BH, Kim KM, Lim I, Choi CW, Suh C, Kim WS, Nam SH, Lee SI, Eom HS, Shin DY, Lim SM. Repeated radioimmunotherapy with -rituximab for patients with low-grade and aggressive relapsed or refractory B cell non-Hodgkin lymphoma. Cancer Chemother Pharmacol 2013;71:945-953.
DOI
|
18 |
Sharkey RM, Goldenberg DM. Targeted therapy of cancer: new prospects for antibodies and Immunoconjugates. CA Cancer J Clin 2006;56:226-243.
DOI
|
19 |
Makvandi M, Dupis E, Engle JW, Nortier FM, Fassbender ME, Simon S, Birnbaum ER, Atcher RW, John KD, Rixe O, Norenberg JP. Alpha-Emitters and Targeted Alpha Therapy in Oncology: from Basic Science to Clinical Investigations. Target Oncol 2018;13:189-203.
DOI
|
20 |
Milenic DE, Brechbeil MW. Targeting of radio-isotopes for cancer therapy. Cancer Biol Ther 2004;3:361-370.
DOI
|
21 |
Zalutsky MR, Pruszynski M. Astatine-211: Production and Availability. Curr Radiopharm 2011;4:177-185.
DOI
|
22 |
Harrison J, Leggett R, Lloyd L, Phipps A, Scott B. Polonium-210 as a poison. J Radiol Prot 2007;27:17-40.
DOI
|
23 |
Kirby HK. Gmelin Handbook of Inorganic Chemistry - Astatine. 8th ed. New York: Springer-Verlag; 1985. p. 95-106.
|
24 |
Guerard F, Gestin JF, Brechbiel MW. Production of [ ]-Astatinated Radiopharmaceuticals and Applications in Targeted a-Particle Therapy. Cancer Biother Radiopharm 2013;28:1-20.
DOI
|
25 |
Henriksen G, Messelt S, Olsen E, Larsen RH. Optimisation of cyclotron production parameters for the reaction related to biomedical use of . Appl Radiat Isot 2001;54:839-844.
DOI
|
26 |
Lebeda O, Jiran R, Ralis J, Stursa J. A new internal cyclotron target system for production of on the cyclotron U-120M. Int J Appl Radiat Isot 2005;63:49-53.
DOI
|
27 |
Schwarz UP, Plascjak P, Beitzel MP, Gansow OA, Eckelman WC, Waldmann TA. Preparation of -labeled humanized anti-Tac using produced in disposable internal and external bismuth targets. Nucl Med Biol 1998;25:89-93.
DOI
|
28 |
Champion J, Alliot C, Huclier S, Deniaud D, Asfari Z, Montavon G. Determination of stability constants between complexing agents and At(I) and At(III) species present at ultra-trace concentrations. Inorganica Chimica Acta 2009;362:2654-2661.
DOI
|
29 |
Alfarano A, Abbas K, Holzwarth U, Bonardi M, Groppi F, Alfassi Z, Menapace E, Gibson PN. Thick target yield measurement of through the nuclear reaction . J Phys Conf Series 2006;41:115-122.
DOI
|
30 |
Yordanov AT, Pozzi O, Carlin S, Akabani G, Zalutsky MR. Wet harvesting of no-carrier-added from an irradiated target for radiopharmaceutical applications. J Radioanalyt Nucl Chem 2004;262:593-599.
DOI
|
31 |
Lindegren S, Back T, Jensen HJ. Dry-distillation of astatine-211 from irradiated bismuth targets: a time-saving procedure with high recovery yields. Appl Radiat Isot 2001;55:157-160.
DOI
|
32 |
Pozzi OR, Zalutsky MR. Radiopharmaceutical chemistry of targeted radiotherapeutics, part 3: alpha-particle-induced radiolytic effects on the chemical behavior of . J Nucl Med 2007;48:1190-1206.
DOI
|
33 |
Friedman AM, Zalutsky MR, Wung W, Buckinham F, Harper PV Jr. Scherr GH, Wainer B, Hunter RL, Appelman EH, Rothberg RM, Fitch FW, Stuart FP, Simonian SJ. Preparation of a biologically stable and immunogenically competent astatinated protein. Int J Nucl Med Biol 1977;4:219-224.
DOI
|
34 |
Pozzi OR, Zalutsky MR. Radiopharmaceutical chemistry of targeted radiotherapeutics, part 1 : Effects of solvent on the degradation of radiohalogenation precursors by astatine-211 -particles. J Nucl Med 2005;46:700-706.
|
35 |
Visser GWM, Deimer EL, Kaspersen FM. The preparation and stability of -astato-imidazoles. Int J Appl Rad Isot 1980;31:275-278.
DOI
|
36 |
Pozzi OR, Zalutsky MR. Radiopharmaceutical chemistry of targeted radiotherapeutics, part 2 : radiolytic effects of alpha-particles influence N-succinimidyl 3- -astatobenzoate synthesis. J Nucl Med 2005;46:1393-1400.
|
37 |
Pozzi OR, Zalutsky MR. Radiopharmaceutical chemistry of targeted radiotherapeutics, part 4: Strategies for labeling at high activities and radiation doses of -particles. Nucl Med Biol 2017;46:43-49.
DOI
|
38 |
Zalutsky MR, Reardon DA, Akabani G, Coleman RE, Friedman AH, Freidman HS, McLendon RE, Wong TZ, Bigner DD. Clinical experience with -emitting astatine-211: treatment of recurrent brain tumor patients with -labeled chimeric 81C6 antitenascin monoclonal antibody 81C6. J Nucl Med 2008;49:30-38.
|
39 |
Wilbur DS, Vessella RL, Stray JE, Goffe DK, Blouke KA, Atcher RW. Preparation and evaluation of para-[ ] astatobenzoyl labeled anti-renal cell carcinoma antibody A6H F(ab')2. In vivo distribution comparison with para-[ ]iodobenzoyl labeled A6H F(ab')2. Nucl Med Biol 1993;20:917-927.
DOI
|
40 |
Persson, MI, Gedda L, Jensen HJ, Lundqvist H, Malmstrom PU, Tolmachev V. Astatinated trastuzumab, a putative agent for radionuclide immunotherapy of ErbB2-expressing tumours. Oncol Rep 2006;15:673-680.
|
41 |
Gdarg PK, Johdn CS, Zalutsky MR. Preparation and preliminary evaluation of 4-[ ]astato-N-piperidinoethyl benzamide. Nucl Med Biol 1995;22:467-473.
DOI
|