Administration of red ginseng regulates microRNA expression in a mouse model of endometriosis |
Lee, Jae Hoon
(Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Park, Ji Hyun (Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine) Won, Bo Hee (Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine) Im, Wooseok (Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine) Cho, SiHyun (Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine) |
1 | Giudice LC, Kao LC. Endometriosis. Lancet 2004;364:1789-99. DOI |
2 | Macer ML, Taylor HS. Endometriosis and infertility: a review of the pathogenesis and treatment of endometriosis-associated infertility. Obstet Gynecol Clin North Am 2012;39:535-49. DOI |
3 | Bulletti C, Coccia ME, Battistoni S, Borini A. Endometriosis and infertility. J Assist Reprod Genet 2010;27:441-7. DOI |
4 | Lee B, Du H, Taylor HS. Experimental murine endometriosis induces DNA methylation and altered gene expression in eutopic endometrium. Biol Reprod 2009;80:79-85. DOI |
5 | Ambros V. The functions of animal microRNAs. Nature 2004;431:350-5. DOI |
6 | Lee B, Sur B, Park J, Kim SH, Kwon S, Yeom M, et al. Ginsenoside rg3 alleviates lipopolysaccharide-induced learning and memory impairments by anti-inflammatory activity in rats. Biomol Ther (Seoul) 2013;21:381-90. DOI |
7 | Lee JH, Min DS, Lee CW, Song KH, Kim YS, Kim HP. Ginsenosides from Korean Red Ginseng ameliorate lung inflammatory responses: inhibition of the MAPKs/NF-κB/c-Fos pathways. J Ginseng Res 2018;42:476-84. DOI |
8 | Guney M, Oral B, Karahan N, Mungan T. Regression of endometrial explants in a rat model of endometriosis treated with melatonin. Fertil Steril 2008;89:934-42. DOI |
9 | Moustafa S, Burn M, Mamillapalli R, Nematian S, Flores V, Taylor HS. Accurate diagnosis of endometriosis using serum microRNAs. Am J Obstet Gynecol 2020;223:557. |
10 | Borghese B, Zondervan KT, Abrao MS, Chapron C, Vaiman D. Recent insights on the genetics and epigenetics of endometriosis. Clin Genet 2017;91:254-64. DOI |
11 | Coon JT, Ernst E. Panax ginseng: a systematic review of adverse effects and drug interactions. Drug Saf 2002;25:323-44. DOI |
12 | Song JH, Kim KJ, Chei S, Seo YJ, Lee K, Lee BY. Korean Red Ginseng and Korean black ginseng extracts, JP5 and BG1, prevent hepatic oxidative stress and inflammation induced by environmental heat stress. J Ginseng Res 2020;44:267-73. DOI |
13 | Kang KA, Kim HS, Kim DH, Hyun JW. The role of a ginseng saponin metabolite as a DNA methyltransferase inhibitor in colorectal cancer cells. Int J Oncol 2013;43:228-36. DOI |
14 | Zhu X, Wang F, Zhao Y, Yang P, Chen J, Sun H, et al. A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice. PLoS Genet 2014;10:e1004589. DOI |
15 | Kim MK, Lee SK, Park JH, Lee JH, Yun BH, Park JH, et al. Ginsenoside Rg3 decreases fibrotic and invasive nature of endometriosis by modulating miRNA-27b: in vitro and in vivo studies. Sci Rep 2017;7:17670. DOI |
16 | Grummer R. Animal models in endometriosis research. Hum Reprod Update 2006;12:641-9. DOI |
17 | In G, Ahn NG, Bae BS, Lee MW, Park HW, Jang KH, et al. In situ analysis of chemical components induced by steaming between fresh ginseng, steamed ginseng, and red ginseng. J Ginseng Res 2017;41:361-9. DOI |
18 | Cao Y, Ye Q, Zhuang M, Xie S, Zhong R, Cui J, et al. Ginsenoside Rg3 inhibits angiogenesis in a rat model of endometriosis through the VEGFR-2-mediated PI3K/Akt/mTOR signaling pathway. PLoS One 2017;12:e0186520. DOI |
19 | Yotova IY, Quan P, Leditznig N, Beer U, Wenzl R, Tschugguel W. Abnormal activation of Ras/Raf/MAPK and RhoA/ROCKII signalling pathways in eutopic endometrial stromal cells of patients with endometriosis. Hum Reprod 2011;26:885-97. DOI |
20 | Sharpe-Timms KL, Zimmer RL, Jolliff WJ, Wright JA, Nothnick WB, Curry TE. Gonadotropin-releasing hormone agonist (GnRH-a) therapy alters activity of plasminogen activators, matrix metalloproteinases, and their inhibitors in rat models for adhesion formation and endometriosis: potential GnRH-a-regulated mechanisms reducing adhesion formation. Fertil Steril 1998;69:916-23. DOI |
21 | Babak T, Zhang W, Morris Q, Blencowe BJ, Hughes TR. Probing microRNAs with microarrays: tissue specificity and functional inference. RNA 2004;10:1813-9. DOI |
22 | Bruner-Tran KL, Herington JL, Duleba AJ, Taylor HS, Osteen KG. Medical management of endometriosis: emerging evidence linking inflammation to disease pathophysiology. Minerva Ginecol 2013;65:199-213. |
23 | Reis FM, Petraglia F, Taylor RN. Endometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis. Hum Reprod Update 2013;19:406-18. DOI |
24 | Akkaya P, Onalan G, Haberal N, Bayraktar N, Mulayim B, Zeyneloglu HB. Doxycycline causes regression of endometriotic implants: a rat model. Hum Reprod 2009;24:1900-8. DOI |
25 | Islimye M, Kilic S, Zulfikaroglu E, Topcu O, Zergeroglu S, Batioglu S. Regression of endometrial autografts in a rat model of endometriosis treated with etanercept. Eur J Obstet Gynecol Reprod Biol 2011;159:184-9. DOI |
26 | Kang S, Min H. Ginseng, the 'immunity boost': the effects of panax ginseng on immune system. J Ginseng Res 2012;36:354-68. DOI |
27 | Son KJ, Choi KR, Lee SJ, Lee H. Immunogenic cell death induced by ginsenoside Rg3: significance in dendritic cell-based anti-tumor immunotherapy. Immune Netw 2016;16:75-84. DOI |
28 | Kim HY, Kim K. Protective effect of ginseng on cytokine-induced apoptosis in pancreatic beta-cells. J Agric Food Chem 2007;55:2816-23. DOI |
29 | Janaszak-Jasiecka A, Bartoszewska S, Kochan K, Piotrowski A, Kalinowski L, Kamysz W, et al. miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells. Sci Rep 2016;6:22775. DOI |
30 | Bjerre MT, Strand SH, Norgaard M, Kristensen H, Rasmussen AK, Mortensen MM, et al. Aberrant DOCK2, GRASP, HIF3A and PKFP hypermethylation has potential as a prognostic biomarker for prostate cancer. Int J Mol Sci 2019;20:1173. DOI |
31 | Lagana AS, Garzon S, Gotte M, Vigano P, Franchi M, Ghezzi F, et al. The pathogenesis of endometriosis: molecular and cell biology insights. Int J Mol Sci 2019;20:5615. DOI |
32 | Seifer BJ, Su D, Taylor HS. Circulating miRNAs in murine experimental endometriosis. Reprod Sci 2017;24:376-81. DOI |
33 | Zhao MD, Sun YM, Fu GF, Du YZ, Chen FY, Yuan H, et al. Gene therapy of endometriosis introduced by polymeric micelles with glycolipid-like structure. Biomaterials 2012;33:634-43. DOI |
34 | Cosar E, Mamillapalli R, Ersoy GS, Cho S, Seifer B, Taylor HS. Serum microRNAs as diagnostic markers of endometriosis: a comprehensive array-based analysis. Fertil Steril 2016;106:402-9. DOI |
35 | Lu Y, Nie J, Liu X, Zheng Y, Guo SW. Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. Hum Reprod 2010;25:1014-25. DOI |
36 | Giudice LC. Clinical practice. Endometriosis. N Engl J Med 2010;362:2389-98. DOI |
37 | Guo SW. Epigenetics of endometriosis. Mol Hum Reprod 2009;15:587-607. DOI |
38 | Souza VR, Mendes E, Casaro M, Antiorio AT, Oliveira FA, Ferreira CM. Description of ovariectomy protocol in mice. In: Guest PC, editor. Pre-clinical models: techniques and protocols. New York: Springer; 2019. p. 303-9. |
39 | Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol 2010;8:e1000412. DOI |
40 | Garcia D, Tarafa IS, Flores I. Effects of a histone methyltransferase inhibitor on fertility on a rat model of endometriosis. J Health Dispar Res Pract 2018;12:33. |
41 | Ashcroft T, Simpson JM, Timbrell V. Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 1988;41:467-70. DOI |
42 | Park JH, Lee SK, Kim MK, Lee JH, Yun BH, Park JH, et al. Saponin extracts induced apoptosis of endometrial cells from women with endometriosis through modulation of miR-21-5p. Reprod Sci 2018;25:292-301. DOI |
43 | Leconte M, Nicco C, Ngo C, Chereau C, Chouzenoux S, Marut W, et al. The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice. Am J Pathol 2011;179:880-9. DOI |
44 | Makker A, Goel MM, Das V, Agarwal A. PI3K-Akt-mTOR and MAPK signaling pathways in polycystic ovarian syndrome, uterine leiomyomas and endometriosis: an update. Gynecol Endocrinol 2012;28:175-81. DOI |
45 | Lebovic DI, Mueller MD, Taylor RN. Immunobiology of endometriosis. Fertil Steril 2001;75:1-10. DOI |
46 | Sidell N, Han SW, Parthasarathy S. Regulation and modulation of abnormal immune responses in endometriosis. Ann N Y Acad Sci 2002;955:159-73. DOI |
47 | Seguinot II, Craig Z, Isidro A. Effects of a histone methyltransferase inhibitor on fertility in an animal model of endometriosis. FASEB J 2019;33(suppl 1):580.1. |
![]() |