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http://dx.doi.org/10.5653/cerm.2014.41.4.151

Association of the neutrophil-to-lymphocyte ratio and CA 125 with the endometriosis score  

Kim, Seul Ki (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital)
Park, Jung Yeon (Department of Obstetrics and Gynecology, Seoul National University Hospital)
Jee, Byung Chul (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital)
Suh, Chang Suk (Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital)
Kim, Seok Hyun (Department of Obstetrics and Gynecology, Seoul National University College of Medicine)
Publication Information
Clinical and Experimental Reproductive Medicine / v.41, no.4, 2014 , pp. 151-157 More about this Journal
Abstract
Objective: To evaluate the association between the severity of endometriosis and the preoperative neutrophil-to-lymphocyte ratio (NLR) and serum level of cancer antigen 125 (CA 125). Methods: Data were obtained from the medical records of 419 patients who underwent laparoscopic conservative surgery for ovarian endometrioma between April 2005 and March 2013. Each patient's preoperative complete blood count was recorded and the endometriosis score was assessed. Results: The endometriosis score was not associated with either the NLR or the serum level of CA 125. The endometriosis score was negatively related to preoperative hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. The only positive association was between NLR and the patients' age. NLR and preoperative serum anti-M$\ddot{u}$llerian hormone level were found to be negatively related. Conclusion: The severity of endometriosis was not associated with the serum level of CA 125 or the NLR. The presence of a negative correlation between the severity of endometriosis and red blood cell dynamics needs further investigation.
Keywords
Blood cell count; CA-125 antigen; Endometriosis; Hemoglobins; Lymphocytes; Neutrophils;
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