Clinical Outcome of Elective Single Embryo Transfer Compared to Elective Double Embryo Transfer Performed at the Cleavage Stage
![]() |
Kang, Sang-Min
(Daegu Maria Fertility Clinic)
Lee, Sang-Won (Daegu Maria Fertility Clinic) Jeong, Hak-Jun (Daegu Maria Fertility Clinic) Chae, Soo-Jin (Seoul Maria Fertility Hospital) Yoon, San-Hyun (Seoul Maria Fertility Hospital) Lim, Jin-Ho (Seoul Maria Fertility Hospital) Lee, Seong-Goo (Daegu Maria Fertility Clinic) |
1 | Conde-Agudelo A, Belizan JM, Lindmark G. Maternal morbidity and mortality associated with multiple gestations. Obstet Gynecol 2000; 95: 899-904. DOI ScienceOn |
2 | Lukassen HG, Braat DD, Wetzels AM, Zielhuis GA, Adang EM, Scheenjes E, et al. Two cycles with single embryo transfer versus one cycle with double embryo transfer: a randomized controlled trial. Hum Reprod 2005; 20: 702-8. DOI ScienceOn |
3 | Gordts S, Campo R, Puttemans P, Brosens I, Valkenburg M, Norre J, et al. Belgian legislation and the effect of elective single embryo transfer on IVF outcome. Reprod Biomed Online 2005; 10: 436-41. DOI ScienceOn |
4 | De Neubourg D, Gerris J, Mangelschots K, Van Royen E, Vercruyssen M, Elseviers M. Single top quality embryo transfer as a model for prediction of early pregnancy outcome. Hum Reprod 2004; 19: 1476-9. DOI ScienceOn |
5 | Martikainen H, Orava M, Lakkakorpi J, Tuomivaara L. Day 2 elective single embryo transfer in clinical practice: better outcome in ICSI cycles. Hum Reprod 2004; 19: 1364-6. DOI ScienceOn |
6 | Veleva Z, Vilska S, Hyden-Granskog C, Tiitinen A, Tapanainen JS, Martikainen H. Elective single embryo transfer in women aged 36-39 years. Hum Reprod 2006; 21: 2098-102. DOI ScienceOn |
7 | Vilska S, Tiitinen A, Hyden-Granskog C, Hovatta O. Elective transfer of one embryo results in an acceptable pregnancy rate and eliminates the risk of multiple birth. Hum Reprod 1999; 14: 2392-5. DOI |
8 | Templeton A, Morris JK, Parslow W. Factors that affect outcome of in-vitro fertilisation treatment. Lancet 1996; 348: 1402-6. DOI ScienceOn |
9 | Saftlas AF, Olson DR, Franks AL, Atrash HK, Pokras R. Epidemiology of preeclampsia and eclampsia in the United States, 1979-1986. Am J Obstet Gynecol 1990; 163: 460-5. DOI ScienceOn |
10 | Xiong X, Saunders LD, Wang FL, Demianczuk NN. Gestational diabetes mellitus: prevalence, risk factors, maternal and infant outcomes. Int J Gynaecol Obstet 2001; 75: 221-8. DOI ScienceOn |
11 | Yoon HG, Yoon SH, Son WY, Kim JG, Im KS, Lim JH. Alternative embryo transfer on day 3 or day 5 for reducing the risk of multiple gestations. J Assist Reprod Genet 2001;18: 262-7. DOI ScienceOn |
12 | Gerris J, De Sutter P, De Neubourg D, Van Royen E, Vander Elst J, Mangelschots K, et al. A real-life prospective health economic study of elective single embryo transfer versus two-embryo transfer in first IVF/ICSI cycles. Hum Reprod 2004; 19: 917-23. DOI ScienceOn |
13 | Van Royen E, Mangelschots K, De Neubourg D, Valkenburg M, Van de Meerssche M, Ryckaert G, et al. Characterization of a top quality embryo, a step towards single-embryo transfer. Hum Reprod 1999; 14: 2345-9. DOI |
14 | Tiitinen A, Halttunen M, Harkki P, Vuoristo P, Hyden-Granskog C. Elective single embryo transfer: the value of cryopreservation. Hum Reprod 2001; 16: 1140-4. DOI ScienceOn |
15 | van Montfoort AP, Fiddelers AA, Janssen JM, Derhaag JG, Dirksen CD, Dunselman GA, et al. In unselected patients, elective single embryo transfer prevents all multiples, but results in significantly lower pregnancy rates compared with double embryo transfer: a randomized controlled trial. Hum Reprod 2006; 21: 338-43. DOI |
16 | Coetsier T, Dhont M. Avoiding multiple pregnancies in in-vitro fertilization: who's afraid of single embryo transfer? Hum Reprod 1998; 13: 2663-4. DOI ScienceOn |
17 | Tiitinen A, Unkila-Kallio L, Halttunen M, Hyden-Granskog C. Impact of elective single embryo transfer on the twin pregnancy rate. Hum Reprod 2003; 18: 1449-53. DOI ScienceOn |
18 | Karlstrom PO, Bergh C. Reducing the number of embryos transferred in Sweden-impact on delivery and multiple birth rates. Hum Reprod 2007; 22: 2202-7. DOI ScienceOn |
19 | Tiitinen A, Hyden-Granskog C, Gissler M. What is the most relevant standard of success in assisted reproduction?: The value of cryopreservation on cumulative pregnancy rates per single oocyte retrieval should not be forgotten. Hum Reprod 2004; 19: 2439-41. DOI ScienceOn |
20 | Strandell A, Bergh C, Lundin K. Selection of patients suitable for one-embryo transfer may reduce the rate of multiple births by half without impairment of overall birth rates. Hum Reprod 2000; 15: 2520-5. DOI ScienceOn |
21 | Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Van de Meerssche M, Valkenburg M. Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria: a prospective randomized clinical trial. Hum Reprod 1999; 14: 2581-7. DOI |
22 | Martikainen H, Tiitinen A, Tomas C, Tapanainen J, Orava M, Tuomivaara L, et al. One versus two embryo transfer after IVF and ICSI: a randomized study. Hum Reprod 2001; 16: 1900-3. DOI ScienceOn |
23 | Thurin A, Hausken J, Hillensjo T, Jablonowska B, Pinborg A, Strandell A, et al. Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization. N Engl J Med 2004; 351: 2392-402. DOI ScienceOn |
24 | Committee A. Current status of assisted reproductive technology in Korea, 2005. Korean J Obstet Gynecol 2008; 51: 1421-47. |
25 | Andersen AN, Goossens V, Gianaroli L, Felberbaum R, de Mouzon J, Nygren KG. Assisted reproductive technology in Europe, 2003. Results generated from European registers by ESHRE. Hum Reprod 2007; 22: 1513-25. DOI ScienceOn |
26 | Blennborn M, Nilsson S, Hillervik C, Hellberg D. The couple's decision-making in IVF: one or two embryos at transfer? Hum Reprod 2005; 20: 1292-7. DOI ScienceOn |
27 | Templeton A, Morris JK. Reducing the risk of multiple births by transfer of two embryos after in vitro fertilization. N Engl J Med 1998; 339: 573-7. DOI ScienceOn |
28 | Jain T, Missmer SA, Hornstein MD. Trends in embryo-transfer practice and in outcomes of the use of assisted reproductive technology in the United States. N Engl J Med 2004; 350: 1639-45. DOI ScienceOn |
29 | Multiple gestation pregnancy. The ESHRE Capri Workshop Group. Hum Reprod 2000; 15: 1856-64. DOI ScienceOn |
30 | Gardner MO, Goldenberg RL, Cliver SP, Tucker JM, Nelson KG, Copper RL. The origin and outcome of preterm twin pregnancies. Obstet Gynecol 1995; 85: 553-7. DOI ScienceOn |
31 | Land JA, Evers JL. Risks and complications in assisted reproduction techniques: Report of an ESHRE consensus meeting. Hum Reprod 2003; 18: 455-7. DOI ScienceOn |
32 | Spellacy WN, Handler A, Ferre CD. A case-control study of 1253 twin pregnancies from a 1982-1987 perinatal data base. Obstet Gynecol 1990; 75: 168-71. |
33 | Bergh C. Single embryo transfer: a mini-review. Hum Reprod 2005; 20: 323-7. DOI |
34 | Wolner-Hanssen P, Rydhstroem H. Cost-effectiveness analysis of in-vitro fertilization: estimated costs per successful pregnancy after transfer of one or two embryos. Hum Reprod 1998; 13: 88-94. DOI ScienceOn |
![]() |