1 |
Zawadski JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome: In Polycystic ovary syndrome Dunaif A, Givens JR, Haseltime F, et al., editors. Boston (MA):Blackwell, 1992: 377-84
|
2 |
Yildiz BO, Yarali H, Oguz H, Bayraktar M. Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003; 88: 2031-6
DOI
ScienceOn
|
3 |
Leibel NI, Baumann EE, Kocherginsky M, Rosenfield RL. Relationship of adolescent polycystic ovary syndrome to parental metabolic syndrome. J Clin Endocrinol Metab 2006;91: 1275-83
DOI
ScienceOn
|
4 |
Kahsar-Miller MD, Nixon C, Boots LR, Go RC, Azziz R. Prevalence of polycystic ovary syndrome (PCOS) in firstdegree relatives of patients with PCOS. Fertil Steril 2001;75: 53-8
DOI
ScienceOn
|
5 |
Givens JR. Familial polycystic ovarian disease. Endocrinol Metab Clin North Am 1988; 17: 771-83
PUBMED
|
6 |
Simoni M, Tempfer CB, Destenaves B, Fauser BC. Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response. Hum Reprod Update 2008; 14: 459-84
DOI
ScienceOn
|
7 |
Ferk P, Perme MP, Teran N, Gersak K. Androgen receptor gene (CAG)n polymorphism in patients with polycystic ovary syndrome. Fertil Steril 2008; 90: 860-3
DOI
ScienceOn
|
8 |
Urbanek M, Legro RS, Driscoll DA, Azziz R, Ehrmann DA, Norman RJ, et al. Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin, Proceedings of the National Academy of Sciences of the United States of America 1999; 96: 8573-8
DOI
ScienceOn
|
9 |
San Millan JL, Sancho J, Calvo RM, Escobar-Morreale HF. Role of the pentanucleotide (tttta)(n) polymorphism in the promoter of the CYP11a gene in the pathogenesis of hirsutism. Fertil Steril 2001; 75: 797-802
DOI
ScienceOn
|
10 |
Gaasenbeek M, Powell BL, Sovio U, Haddad L, Gharani N, Bennett A, et al. Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone. J Clin Endocrinol Metab 2004; 89: 2408-13
DOI
ScienceOn
|
11 |
Wang Y, Wu X, Cao Y, Yi L, Chen J. A microsatellite polymorphism (tttta)n in the promoter of the CYP11a gene in Chinese women with polycystic ovary syndrome. Fertil Steril 2006; 86: 223-6
DOI
ScienceOn
|
12 |
Echiburu B, Perez-Bravo F, Maliqueo M, Sanchez F, Crisosto N, Sir-Petermann T. Polymorphism T --> C (-34 base pairs) of gene CYP17 promoter in women with polycystic ovary syndrome is associated with increased body weight and insulin resistance: a preliminary study. Metabolism 2008; 57:1765-71
DOI
ScienceOn
|
13 |
Park JM, Lee EJ, Ramakrishna S, Cha DH, Baek KH. Association study for single nucleotide polymorphisms in the CYP17A1 gene and polycystic ovary syndrome. Int J Mol Med 2008; 22: 249-54
PUBMED
|
14 |
Gonzalez A, Abril E, Roca A, Aragon MJ, Figueroa MJ, Velarde P, et al. Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients. J Clin Endocrinol Metab 2003; 88: 5529-36
DOI
ScienceOn
|
15 |
Vollmert C, Hahn S, Lamina C, Huth C, Kolz M, Schopfer-Wendels A, et al. Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians. Am J Physiol Endocrinol Metab 2007; 292: E836-44
DOI
ScienceOn
|
16 |
Haddad L, Evans JC, Gharani N, Robertson C, Rush K, Wiltshire S, et al. Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. J Clin Endocrinol Metab 2002; 87: 2606-10
DOI
ScienceOn
|
17 |
Marquez JL, Pacheco A, Valdes P, Salazar LA. Association between CAPN10 UCSNP-43 gene polymorphism and polycystic ovary syndrome in Chilean women. Clin Chim Acta 200; 398: 5-9
DOI
ScienceOn
|
18 |
Escobar-Morreale HF, Peral B, Villuendas G, Calvo RM, Sancho J, San Millan JL. Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism. Fertil Steril 2002; 77: 581-7
DOI
ScienceOn
|
19 |
Azziz R. Polycystic ovary syndrome, insulin resistance, and molecular defects of insulin signaling. J Clin Endocrinol Metab 2002; 87: 4085-7
DOI
ScienceOn
|
20 |
Krook A, Kumar S, Laing I, Boulton AJ, Wass JA, O'Rahilly S. Molecular scanning of the insulin receptor gene in syndromes of insulin resistance. Diabetes 1994; 43: 357-68
DOI
ScienceOn
|
21 |
Jin L, Zhu XM, Luo Q, Qian Y, Jin F, Huang HF. A novel SNP at exon 17 of INSR is associated with decreased insulin sensitivity in Chinese women with PCOS. Mol Hum Reprod 2006; 12: 151-5
DOI
ScienceOn
|
22 |
Sesti G, Federici M, Hribal ML, Lauro D, Sbraccia P, Lauro R. Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. FASEB J 2001; 15: 2099-111
DOI
ScienceOn
|
23 |
Korhonen S, Heinonen S, Hiltunen M, Helisalmi S, Hippelainen M, Koivunen R, et al. Polymorphism in the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome. Hum Reprod 2003;18: 540-3
DOI
ScienceOn
|
24 |
Ehrmann DA, Tang X, Yoshiuchi I, Cox NJ, Bell GI. Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab 2002; 87: 4297-300
DOI
ScienceOn
|
25 |
Villuendas G, Botella-Carretero JI, Roldan B, Sancho J, Escobar-Morreale HF, et al. Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls. Hum Reprod 2005; 20:3184-91
DOI
ScienceOn
|
26 |
Valdes P, Cerda A, Barrenechea C, Kehr M, Soto C, Salazar LA. No association between common Gly972Arg variant of the insulin receptor substrate-1 and polycystic ovary syndrome in Southern Chilean women. Clin Chim Acta 2008; 390: 63-6
DOI
PUBMED
ScienceOn
|
27 |
Lee EJ, Oh BS, Lee JY, Kim K, Park JM, Baek KH. Association study between single nucleotide polymorphisms in the VEGF gene and polycystic ovary syndrome. Fertil Steril 2008; 89: 1751-9
DOI
ScienceOn
|
28 |
Kim JJ, Choi YM, Choung SH, Yoon SH, Lee GH, Moon SY. Estrogen receptor gene +1730 G/A polymorphism in women with polycystic ovary syndrome. Fertil Steril 2009 2009 Jan 29 [Epub ahead of print]
|
29 |
Hosokawa K, Ottander U, Wahlberg P, Ny T, Cajander S, Olofsson IJ. Dominant expression and distribution of oestrogen receptor beta over oestrogen alpha in the human corpus luteum. Mol Hum Reprod 2001; 7: 137-45
DOI
ScienceOn
|
30 |
Marszalek B, Lacinski M, Babych N, Capla E, Biernacka-
Lukanty J, Warenik-Szymankiewicz A, et al. Investigations on the genetic polymorphism in the region of CYP17 gene encoding 5'-UTR in patients with polycystic ovarian syndrome. Gynecol Endocrinol 2001; 15: 123-8
PUBMED
|
31 |
Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006; 6: 772-83
DOI
ScienceOn
|
32 |
Unluturk U, Harmanci A, Kocaefe C, Yildiz BO. The Genetic Basis of the Polycystic Ovary Syndrome: A Literature Review Including Discussion of PPAR- PPAR Research 2007;2007: 49109
|
33 |
Waterworth DM, Bennett ST, Gharani N, McCarthy MI, Hague S, Batty S, et al. Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome. Lancet 1997; 349: 986-90
DOI
ScienceOn
|
34 |
Techatraisak K, Conway GS, Rumsby G. Frequency of a polymorphism in the regulatory region of the 17 alphahydroxylase-17,20-lyase (CYP17) gene in hyperandrogenic states. Clin Endocrinol (Oxf) 1997; 46: 131-4
DOI
ScienceOn
|
35 |
Erdogan M, Karadeniz M, Berdeli A, Alper G, Caglayan O, Yilmaz C. The relationship of the interleukin-6 -174 G>C gene polymorphism with oxidative stress markers in Turkish polycystic ovary syndrome patients. J Endocrinol Invest 2008;31: 624-9
PUBMED
ScienceOn
|
36 |
Gharani N, Waterworth DM, Batty S, White D, Gilling-Smith C, Conway GS, et al. Association of the steroid synthesis gene CYP11a with polycystic ovary syndrome and hyperandrogenism. Hum Mol Genet 1997; 6: 397-402
DOI
ScienceOn
|
37 |
Wang Y, Wu X, Cao Y, Yi L, Fan H, Chen J. Polymorphisms of the peroxisome proliferator-activated receptor-gamma and its coactivator-1alpha genes in Chinese women with polycystic ovary syndrome. Fertil Steril 2006; 85: 1536-40
DOI
PUBMED
ScienceOn
|
38 |
Shah NA, Antoine HJ, Pall M, Taylor KD, Azziz R, Goodarzi MO. Association of Androgen Receptor CAG Repeat Polymorphism and Polycystic Ovary Syndrome. J Clin Endocrinol Metab 2008; 93: 1939-45
DOI
ScienceOn
|
39 |
Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998; 83: 3078-82
DOI
ScienceOn
|
40 |
Vink JM, Sadrzadeh S, Lambalk CB, Boomsma DI. Heritability of polycystic ovary syndrome in a Dutch twin-family study. J Clin Endocrinol Metab 2006; 91: 2100-4
DOI
ScienceOn
|
41 |
Liu Q, Hong J, Cui B, Zhang Y, Gu W, Chi Z. Androgen receptor gene CAGn trinucleotide repeats polymorphism in Chinese women with polycystic ovary syndrome. Endocr 2008; 33: 165-70
DOI
ScienceOn
|
42 |
Xita N, Tsatsoulis A, Chatzikyriakidou A, Georgiou I. Association of the (TAAAA)n repeat polymorphism in the sex hormone-binding globulin (SHBG) gene with polycystic ovary syndrome and relation to SHBG serum levels. J Clin Endocrinol Metab 2003; 88: 5976-80
DOI
ScienceOn
|
43 |
Lee EJ, Yoo KJ, Kim SJ, Lee SH, Cha KY, Baek KH. Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population. Fertil Steril 2006; 86: 380-4
DOI
ScienceOn
|
44 |
Witchel SF, Kahsar-Miller M, Aston CE, White C, Azziz R. Prevalence of CYP21 mutations and IRS1 variant among women with polycystic ovary syndrome and adrenal androgen excess. Fertil Steril 2005; 83: 371-5
DOI
ScienceOn
|
45 |
Roldan B, San Millan JL, Escobar-Morreale HF. Genetic basis of metabolic abnormalities in polycystic ovary syndrome:implications for therapy. Am J Pharmacogenomics 2004; 4: 93-107
DOI
ScienceOn
|
46 |
Kim JJ, Choung SH, Choi YM, Yoon SH, SH Kim, Moon SY. Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome. Fertil Steril 2008;90: 2318-23
DOI
ScienceOn
|
47 |
Mohlig M, Jurgens A, Spranger J, Hoffmann K, Weickert MO, Schlosser HW, et al. The androgen receptor CAG repeat modifies the impact of testosterone on insulin resistance in women with polycystic ovary syndrome. Eur J Endocrinol 2006; 155: 127-30
DOI
ScienceOn
|
48 |
El Mkadem SA, Lautier C, Macari F, Molinari N, Lefebvre P, Renard E, et al. Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome. Diabetes 2001; 50: 2164-8
DOI
ScienceOn
|
49 |
Ertunc D, Tok EC, Aktas A, Erdal EM, Dilek S. The importance of IRS-1 Gly972Arg polymorphism in evaluating the response to metformin treatment in polycystic ovary syndrome. Hum Reprod 2005; 20: 1207-12
DOI
ScienceOn
|
50 |
Legro RS, Driscoll D, Strauss JF 3rd, Fox J, Dunaif A. Evidence for a genetic basis for hyperadrogenemia in polycystic ovary syndrome. Proc Natl Acad Sci U S A 1998; 95:14956-60
DOI
ScienceOn
|
51 |
Misfud A, Ramirez S, Yong EL. Androgen receptor gene CAG trinucleotide repeats in anovulatory infertility and polycystic ovaries. J Clin Endocrinol Metab 2000; 85: 3484-8
DOI
ScienceOn
|
52 |
Ferriman D, Purdie AW. The inheritance of polycystic ovarian disease and a possible relationship to premature balding. Clin Endocrinol 1979; 11: 291-300
DOI
|
53 |
Cousin P, Calemard-Michel L, Lejeune H, Raverot G, Yessaad N, Emptoz-Bonneton A, et al. Influence of SHBG gene pentanucleotide TAAAA repeat and D327N polymorphism on serum sex hormone- binding globulin concentration in hirsute women. J Clin Endocrinol Metab 2004; 89: 917-24
DOI
ScienceOn
|
54 |
Lee EJ, Oh B, Lee JY, Kimm K, Lee SH, Baek KH. A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. Fertil Steril 2008; 89: 1213-20
DOI
ScienceOn
|
55 |
Kim JJ, Choi YM, Hong MA, Hwang SS, Yoon SH, Chae SJ, et al. Phosphatidylinositol 3-kinase p85a regulatory subunit gene Met326Ile polymorphism in women with polycystic ovary syndrome. Hum Reprod 2009 Feb 13 [Epub ahead of print]
|
56 |
Hague WM, Adams J, Reeders ST, Peto TE, Jacobs HS. Familial polycystic ovaries: a genetic disease? Clin Endocrinol 1988; 29: 593-605
DOI
|
57 |
Sir-Petermann T, Angel B, Maliqueo M, Santos JL, Riesco MV, Toloza H, et al. Insulin secretion in women who have polycystic ovary syndrome and carry the Gly972Arg variant of insulin receptor substrate-1 in response to a high-glycemic or low-glycemic carbohydrate load. Nutrition 2004; 20: 905-10
DOI
ScienceOn
|
58 |
Nestler JE, Jakubowicz DJ, de Vargas AF, Brik C, Quintero N, Medina F. Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system. J Clin Endocrinol Metab 1998; 83: 2001-5
|
59 |
Diamanti-Kandarakis E, Bartzis MI, Zapanti ED, Spina GG, Filandra FA, Tsianateli TC, et al. Polymorphism T-->C (-34 bp) of gene CYP17 promoter in Greek patients with polycystic ovary syndrome. Fertil Steril 1999; 71: 431-5
DOI
PUBMED
ScienceOn
|
60 |
Norman RJ, Masters S, Hague W. Hyperinsulinemia is common in family members of women with polycystic ovary syndrome. Fertil Steril 1996; 66: 942-7
PUBMED
ScienceOn
|
61 |
Nestler JE, Powers LP, Matt DW, Steingold KA, Plymate SR, Rittmaster RS, et al. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. J Clin Endocrinol Metab 1991; 72: 83-9
DOI
PUBMED
|
62 |
Orio F Jr, Palomba S, Cascella T, Di Biase S, Labella D, Russo T, et al. Lack of an association between peroxisome proliferator-activated receptor-gamma gene Pro12Ala polymorphism and adiponectin levels in the polycystic ovary syndrome. J Clin Endocrinol Metab 2004; 89: 5110-5
DOI
ScienceOn
|
63 |
Kim JJ, Choi YM, Yoon SH, Choung SH, Choi DS, Ku SY, et al. CYP11alpha (tttta)n Microsatellite Polymorphism in Korean Patients with Polycystic Ovary Syndrome. Korean J Fertil Steril 2004; 31: 245-52
|
64 |
Xita N, Georgiou I, Lazaros L, Psofaki V, Kolios G, Tsatsoulis A. The synergistic effect of sex hormone-binding globulin and aromatase genes on polycystic ovary syndrome phenotype. Eur J Endocrinol 2008; 158: 861-5
DOI
ScienceOn
|
65 |
Dilek S, Ertunc D, Tok EC, Erdal EM, Aktas A. Association of Gly972Arg variant of insulin receptor substrate-1 with metabolic features in women with polycystic ovary syndrome. Fertil Steril 2005; 84: 407-12
DOI
ScienceOn
|
66 |
Baba T, Endo T, Sata F, Honnma H, Kitajima Y, Hayashi T, et al. Polycystic ovary syndrome is associated with genetic polymorphism in the insulin signaling gene IRS-1 but not ENPP1 in a Japanese population. Life Sci 2007; 16: 850-4
DOI
ScienceOn
|
67 |
Asuncion M, Calvo RM, San Millan JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab 2000; 85: 2434
-8
DOI
ScienceOn
|
68 |
Franks S, Gharani N, Waterworth D, et al. The genetic basis of polycystic ovary syndrome. Hum Reprod 1997; 12: 2641-8
DOI
ScienceOn
|
69 |
Panidis D, Kourtis A, Kukuvitis A, Farmakiotis D, Xita N, Georgiou I, et al. Association of the T45G polymorphism in exon 2 of the adiponectin gene with polycystic ovary syndrome: role of Delta4-androstenedione. Hum Reprod 2004; 19: 1728-33
DOI
ScienceOn
|
70 |
Chen ZJ, Shi YH, Zhao YR, Li Y, Tang R, Zhao LX, et al. Correlation between single nucleotide polymorphism of insulin receptor gene with polycystic ovary syndrome. Zhonghua Fu Chan Ke Za Zhi 2004; 39: 582-5
PUBMED
|
71 |
Cooper DN, Clayton JF. DNA polymorphism and the study of disease associations. Hum Genet 1988; 78: 299-312
DOI
PUBMED
|
72 |
Jaaskelainen J, Korhonen S, Voutilainen R, Hippeläinen M, Heinonen S. Androgen receptor gene CAG length polymor phism in women with polycystic ovary syndrome. Fertil Steril 2005; 83: 1724-8
DOI
ScienceOn
|
73 |
Kahsar-Miller M, Boots LR, Bartolucci A, Azziz R. Role of a CYP17 polymorphism in the regulation of circulating dehydroepiandrosterone sulfate levels in women with polycystic ovary syndrome. Fertil Steril 2004; 82: 973-5
DOI
ScienceOn
|
74 |
Petry CJ, Ong KK, Michelmore KF, Artigas S, Wingate DL, Balen AH, et al. Association of aromatase (CYP 19) gene variation with features of hyperandrogenism in two populations of young women. Hum Reprod 2005; 20: 1837-43
DOI
ScienceOn
|
75 |
Kamat BR, Brown LF, Manseau EJ, Senger DR, Dvorak HF. Expression of vascular permeability factor/vascular endothelial growth factor by human granulosa and theca lutein cells. Role in corpus luteum development. Am J Pathol 1995; 146:157-65
PUBMED
ScienceOn
|
76 |
Xita N, Georgiou I, Lazaros L, Psofaki V, Kolios G, Tsatsoulis A. The role of sex hormone-binding globulin and androgen receptor gene variants in the development of polycystic ovary syndrome. Hum Reprod 2008; 23: 693-8
DOI
ScienceOn
|
77 |
Diamanti-Kandarakis E, Bartzis MI, Bergiele AT, Tsianateli TC, Kouli CR. Microsatellite polymorphism (tttta)(n) at -528 base pairs of gene CYP11alpha influences hyperandrogenemia in patients with polycystic ovary syndrome. Fertil Steril 2000; 73: 735-41
DOI
PUBMED
ScienceOn
|
78 |
Siegel S, Futterweit W, Davies TF, Concepcion ES, Greenberg DA, Villanueva R, et al. A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome. Fertil Steril 2002; 78: 1240-3
DOI
ScienceOn
|
79 |
Hara M, Alcoser SY, Qaadir A, Beiswenger KK, Cox NJ, Ehrmann DA. Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene. J Clin Endocrinol Metab 2002;87: 772-5
DOI
ScienceOn
|
80 |
Lunde O, Magnus P, Sandvik L, Hoglo S. Familial clustering in the polycystic ovarian syndrome. Gynecol Obstet Invest 1989; 28: 23-30
DOI
ScienceOn
|
81 |
Lee JY, Lee WJ, Hur SE, Sung YA, Chung HW. 111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women. Fertil Steril 2008 Aug 11[Epub ahead of print]
DOI
ScienceOn
|
82 |
Balen AH, Laven JS, Tan SL, Dewailly D. Ultrasound assessment of the polycystic ovary: international consensus definitions. Human Reprod Update 2003; 9: 505-14
DOI
ScienceOn
|
83 |
Lehrke M, Lazar MA. The many faces of PPARgamma. Cell 2005; 123: 993-9
DOI
ScienceOn
|
84 |
Zhang N, Shi YH, Hao CF, Gu HF, Li Y, Zhao YR, et al. Association of +45G15G(T/G) and +276(G/T) polymorphisms in the ADIPOQ gene with polycystic ovary syndrome among Han Chinese women. Eur J Endocrinol 2008; 158:255-60
DOI
ScienceOn
|
85 |
San Millan JL, Corton M, Villuendas G, Sancho J, Peral B, Escobar-Morreale HF. Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity. J Clin Endocrinol Metab 2004; 89: 2640-6
DOI
ScienceOn
|
86 |
Pusalkar M, Meherji P, Gokral J, Chinnaraj S, Maitra A. CYP11A1 and CYP17 promoter polymorphisms associate with hyperandrogenemia in polycystic ovary syndrome. Fertil Steril 2008 Aug 23 [Epub ahead of print]
|
87 |
Heinonen S, Korhonen S, Helisalmi S, Koivunen R, Tapanainen J, Hippelainen M, et al. Associations between two single nucleotide polymorphisms in the adiponectin gene and polycystic ovary syndrome. Gynecol Endocrinol 2005; 21: 165-9
DOI
ScienceOn
|
88 |
Hahn S, Fingerhut A, Khomtsiv U, Khomtsiv L, Tan S, Quadbeck B, et al. The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lower hirsutism score and increased insulin sensitivity in women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 2005; 62: 573-9
DOI
ScienceOn
|
89 |
Haap M, Machicao F, Stefan N, Thamer C, Tschritter O, Schnuck F, et al. Genetic determinants of insulin action in polycystic ovary syndrome. Exp Clin Endocrinol Diabetes 2005; 113: 275-81
DOI
ScienceOn
|
90 |
Ehrmann DA, Schwarz PE, Hara M, Tang X, Horikawa Y, Imperial J, et al. Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab 2002; 87: 1669-73
DOI
ScienceOn
|
91 |
Tok EC, Aktas A, Ertunc D, Erdal EM, Dilek S. Evaluation of glucose metabolism and reproductive hormones in polycystic ovary syndrome on the basis of peroxisome proliferatoractivated receptor (PPAR)-gamma2 Pro12Ala genotype. Hum Reprod 2005; 20: 1590-5
DOI
ScienceOn
|
92 |
Kaushal R, Parchure N, Bano G, Kaski JC, Nussey SS. Insulin resistance and endothelial dysfunction in the brothers of Indian subcontinent Asian women with polycystic ovaries. Clin Endocrinol 2004; 60: 322-8
DOI
ScienceOn
|
93 |
Krege JH, Hodgin JB, Couse JF, Enmark E, Wagner M, Mahler JF, et al. Generation and reproductive phenotypes of mice lacking estrogen receptor- . Proc Natl Acad Sci USA 1998; 95: 15677-82
DOI
ScienceOn
|
94 |
Govind A, Obhrai MS, Clayton RN. Polycystic ovaries are inherited as an autosomal dominant trait: analysis of 29 polycystic ovary syndrome and 10 control families. J Clin Endocrinol Metab 1999; 84: 38-43
DOI
ScienceOn
|
95 |
Ferk P, Teran N, Gersak K. The (TAAAA)n microsatellite polymorphism in the SHBG gene influences serum SHBG levels in women with polycystic ovary syndrome. Hum Reprod 2007; 22: 1031-6
DOI
ScienceOn
|
96 |
Enmark E, Pelto-Huikko M, Grandien K, Lagercrantz S, Lagercrantz J, Fried G, et al. Human estrogen receptor gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab 1997; 82: 4258-65
DOI
ScienceOn
|
97 |
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 2000; 26:163-75
DOI
ScienceOn
|
98 |
Wiltgen D, Furtado L, Kohek MB, Spritzer PM. CAPN10 UCSNP-43, UCSNP-19 and UCSNP-63 polymorphisms and metabolic syndrome in polycystic ovary syndrome. Gynecol Endocrinol 2007; 23: 173-8
DOI
ScienceOn
|
99 |
Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev 1997; 18: 774-800
DOI
PUBMED
ScienceOn
|
100 |
Antoine HJ, Pall M, Trader BC, Chen YD, Azziz R, Goodarzi MO. Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome. Fertil Steril 2007; 87: 862-9
DOI
ScienceOn
|
101 |
Barbieri RL, Makris A, Randall RW, Daniels G, Kistner RW, Ryan KJ. Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism. J Clin Endocrinol Metab 1986; 62: 904-10
DOI
PUBMED
|
102 |
Carey AH, Chan KL, Short F, White D, Williamson R, Franks S. Evidence for a single gene effect in polycystic ovaries an male pattern baldness. Clin Endocrinol 1993; 38: 653-8
DOI
ScienceOn
|
103 |
Hickey T, Chandy A, Norman RJ. The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome. J Clin Endocrinol Metab 2002;87: 161-5
DOI
ScienceOn
|
104 |
Xita N, Georgiou I, Chatzikyriakidou A, Vounatsou M, Papassotiriou GP, Papassotiriou I, et al. Effect of adiponectin gene polymorphisms on circulating adiponectin and insulin resistance indexes in women with polycystic ovary syndrome. Clin Chem 2005; 51: 416-23
DOI
ScienceOn
|
105 |
Duffy DM, Chaffin CL, Stouffer RL. Expression of estrogen receptor alpha and beta in the rhesus monkey corpus luteum during the menstrual cycle: regulation by luteinizing hormone and progesterone. Endocrinology 2000; 141: 1711-7
DOI
PUBMED
ScienceOn
|