Anti-ulcer effects of HT074 on HCl/EtOH induced gastric injury |
Kim, Young-Sik
(Dept. of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University)
Park, HyoJin (Korea Institute of Science and Technology for Eastern Medicine, NeuMed Co., Ltd.) Song, Jungbin (Dept. of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University) Lee, Donghun (Dept. of Herbal Pharmacology, College of Korean Medicine, Gachon University) Kim, Hocheol (Dept. of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University) |
1 | Shaw S, Herbert V, Colman N, Jayatilleke E. Effect of ethanol-generated free radicals on gastric intrinsic factor and glutathione. Alcohol. 1990 ; 7(2) : 153-7. DOI |
2 | Zhou A, Wu H, Pan J, Wang X, Li J, Wu Z, Hui A. Synthesis and Evaluation of Paeonol Derivatives as Potential Multifunctional Agents for the Treatment of Alzheimer’s Disease. Molecules. 2015 ; 20 : 1304-18. DOI |
3 | Park EJ, Kim Y, Kim J. Acylated flavonol glycosides from the flower of Inula britannica. J. Nat. Prod. 2000 ; 63 : 34-6. DOI |
4 | Oates PJ, Hakkinen JP. Studies on the mechanism of ethanol-induced gastric damage in rats. Gastroenterology. 1988 ; 94(1) : 10-21. DOI |
5 | Robert A, Nezamis JE, Lancaster C, Hanchar AJ. Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury. Gastroenterology. 1979 ; 77(3) : 433-43. |
6 | Ishii Y, Fujii Y, Homma M. Gastric acid stimulating action of cysteamine in the rat. Eur J Pharmacol. 1976 ; 36(2) : 331-6. DOI |
7 | Kurebayashi Y, Ikeda T, Osada Y. Cytoprotective action of cetraxate against HCl.ethanol-induced gastric lesion in rats. Jpn J Pharmacol. 1988 ; 46(1) : 17-25. DOI |
8 | Nordin N, Salama SM, Golbabapour S, Hajrezaie M, Hassandarvish P, Kamalidehghan B, Majid NA, Hashim NM, Omar H, Fadaienasab M, Karimian H, Taha H, Ali HM, Abdulla MA. Anti-ulcerogenic effect of methanolic extracts from Enicosanthellum pulchrum (King) Heusden against ethanol-induced acute gastric lesion in animal models. PLoS One. 2014 ; 9(11) : e111925. DOI |
9 | Yu C, Mei XT, Zheng YP, Xu DH. Gastroprotective effect of taurine zinc solid dispersions against absolute ethanol-induced gastric lesions is mediated by enhancement of antioxidant activity and endogenous PGE2 production and attenuation of NO production. Eur J Pharmacol. 2014 ; 740 : 329-36. DOI |
10 | Oyagi A, Ogawa K, Kakino M, Hara H. Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice. BMC Complement Altern Med. 2010 ; 10 : 45. DOI |
11 | Nartey ET, Ofosuhene M, Agbale CM. Antiulcerogenic activity of the root bark extract of the African laburnum "Cassia sieberiana" and its effect on the anti-oxidant defence system in rats. BMC Complement Altern Med. 2012 ; 12 : 247. DOI |
12 | Chen P, Shen Y, Shi H, Ma X, Lin B, Xiao T, Wu F, Zhu J, Li Z, Xiao J, Li X, Zhang H, Geng F. Gastroprotective effects of Kangfuxin-against ethanol-induced gastric ulcer via attenuating oxidative stress and ER stress in mice. Chem Biol Interact. 2016 ; 260 : 75-83. DOI |
13 | Xu C, Ding C, Zhou N, Ruan XM, Guo BX. A polysaccharide from Aloe vera L. var. chinensis (Haw.) Berger prevents damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo. Journal of Functional Foods. 2016 ; 24 : 501-12. DOI |
14 | Sofidiya MO, Orisaremi CO, Sansaliyu I, Adetunde TO. Gastroprotective and antioxidant potentials of ethanolic stem bark extract of Margaritaria discoidea (Euphorbiaceae) in rats. J Ethnopharmacol. 2015 ; 171 : 240-6. DOI |
15 | Bonamin F, Moraes TM, Kushima H, Silva MA, Rozza AL, Pellizzon CH, Bauab TM, Rocha LR, Vilegas W, Hiruma-Lima CA. Can a Strychnos species be used as antiulcer agent? Ulcer healing action from alkaloid fraction of Strychnos pseudoquina St. Hil. (Loganiaceae). J Ethnopharmacol. 2011 ; 138(1) : 47-52. DOI |
16 | Corfield AP, Myerscough N, Longman R, Sylvester P, Arul S, Pignatelli M: Mucins and mucosal protection in the gastrointestinal tract: new prospects for mucins in the pathology of gastrointestinal disease. Gut 2000 ; 47 : 589-94. DOI |
17 | Salaga M, Zatorski H, Zielinska M, Mosinska P, Timmermans JP, Kordek R, Storr M, Fichna J. Highly selective CB2 receptor agonist A836339 has gastroprotective effect on experimentally induced gastric ulcers in mice. Naunyn Schmiedebergs Arch Pharmacol. 2017 ; 390(10) : 1015-27. DOI |
18 | Meister A, anderson ME. Glutathione. Annu. Rev. Biochem. 1983 ; 52 : 711-60. DOI |
19 | Starke PE, Farber JL. Endogenous defence against the cytotoxicity of hydrogen peroxide in cultured rat hepatocytes. J. Biol. Chem. 1985 ; 260 : 86-92. |
20 | Kim YG, Yang GH, Cho SI. Anti-oxidative Effects of Dendrobii Herba on Toxic Agent Induced Kidney Cell Injury. Kor. J. Herbology. 2005 ; 20(4) : 53-60. |
21 | Nam SY, Kim N, Lee CS, Choi KD, Lee HS, Jung HC, Song IS. Gastric mucosal protection via enhancement of MUC5AC and MUC6 by geranylgeranylacetone. Dig Dis Sci. 2005 ; 50(11) : 2110-20. DOI |
22 | Ho SB, Takamura K, Anway R, Shekels LL, Toribara NW, Ota H. The adherent gastric mucous layer is composed of alternating layers of MUC5AC and MUC6 mucin proteins. Dig Dis Sci. 2004 ; 49(10) : 1598-606. DOI |
23 | Ozbakis, GD, and Gursan N. Effects of Momordica charantia L.(Cucurbitaceae) on indomethacininduced ulcer model in rats. The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology. 2005 ; 16(2) : 85-8. |
24 | Makki AM, Aldaqal SM, Alorabi SH, Nemri IA, Alajami MM. Chronic Gastritis in Morbidly Obese Patients with Sleeve Gastrectomy. Electronic Physician. 2016 ; 8(1) : 1786-90. DOI |
25 | Health Insurance Review & Assessment service, National health insurance service. National Health Insurance Statistical Yearbook. 2017. |
26 | Song YK, Jin SK, Han ES, Ahn MR, Jung JY, Lee R, Cho IY, Kim DS, Ji EH, Park HY, Oh JM, Shin W, Lee SH, Kim IK. Guideline for the Clinical Trials Evaluation for Gastritis. YAKHAK HOEJI. 2011 ; 55(4) : 1-26. |
27 | Shay H. Etiology of peptic ulcer. Am J Dig Dis. 1961 ; 6 : 29-49. DOI |
28 | Lee A, Lee J, Kim M, Shin M, Shin S, Seo B, Kwon O, Roh SS. Protective Effects of a Lycium chinense Ethanol Extract through Anti-oxidative Stress on Acute gastric lesion mice. Kor. J. Herbol. 2015; 30(6):63-8. DOI |
29 | Feldman M, Burton ME. Histamine2-receptor antagonists. Standard therapy for acid-peptic diseases. 1. N Engl J Med. 1990 ; 323(24) : 1672-80. DOI |
30 | Johnson DA, Oldfield EC. Reported side effects and complications of long-term proton pump inhibitor use: dissecting the evidence. Clin. Gastroenterol. Hepatol. 2013 ; 11 : 458-64. DOI |
31 | Karunakaran R, Ira Thabrew M, Thammitiyagodage GM, Galhena BP, Menuka Arawwawala LDA. The gastroprotective effect of ethyl acetate fraction of hot water extract of Trichosanthes cucumerina Linn and its underlying mechanisms. BMC Complementary and Alternative Medicine. 2017 ; 17 : 312. DOI |
32 | Jalving M, Koornstra JJ, Wesseling J, Boezen HM, DE Jong S, Kleibeuker JH. Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy. Aliment Pharmacol Ther. 2006 ; 24(9) : 1341-8. DOI |
33 | Raghunath AS, O'Morain C, Mcloughlin RC. The long-term use of proton-pump inhibitors. Alimentary Pharmacology & Therapeutics. 2005 ; 22(s1) : 55-63. DOI |
34 | Granger DN, Kubes P. The microcirculation and inflammation: modulation of leukocyte-endothelia cell adhesion. J Leukoc Biol. 1994 ; 55(5) : 662-75. DOI |
35 | Kuipers EJ, Lundell L, Klinkenberg-Knol EC, Havu N, Festen HP, Liedman B, Lamers CB, Jansen JB, Dalenback J, Snel P, Nelis GF, Meuwissen SG. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med. 1996 ; 334(16) : 1018-22. DOI |
36 | Song CS, Park DI. Concerns on Atrophic Gastritis and Neoplasia: Unsafe Perspective. The Korean Journal of Medicine. 2011 ; 81(1) : 6-10. |
37 | Nehra AK, Alexander JA, Loftus CG, Nehra V. Proton Pump Inhibitors: Review of Emerging Concerns. Mayo Clin Proc. 2018 ; 93(2) : 240-6. DOI |
38 | Jeong CS, Hyun JE, Kim YS. Anti-oxidative Effect of Ginsenoside Rb1 on the HCl, Ethanol-Induced Gastric Tissue in Rats. Korean J. pharmacogn. 2002 ; 33(3) : 252-6. |
39 | Suzuki H, Nishizawa T, Tsugawa H, Mogami S, Hibi T. Role of oxidative stress in stomach disorders. J. Clin. Biochem. Nutr. 2012 ; 50 : 35-9. |
40 | de Carvalho CA, Fernandes KM, Matta SLP, da Silva MB, de Oliveira LL, Fonseca CC. Evaluation of antiulcerogenic activity of aqueous extract of Brassica oleracea var. capitata (cabbage) on Wistar rat gastric ulceration. Arq. Gastroenterol. 2011 ; 48 : 276-82. DOI |
41 | Kim MY, Kwon OJ, Noh JS, Roh SS. Inhibitory Activities of Water extracts of Black Ginseng on HCl/Ethanol Induced Acute Gastritis through Anti-Oxidant Effect. J Korean Soc Food Sci Nutr. 2016 ; 45(9) : 1249-56. DOI |
42 | Suo H, Zhao X, Qian Y, Sun P, Zhu K, Li J, Sun B. Lactobacillus fermentum Suo Attenuates HCl/Ethanol Induced Gastric Injury in Mice through Its Antioxidant Effects. Nutrients. 2016 ; 8(3) : 155. DOI |
43 | Parker S, May B, Zhang C, Zhang AL, Lu C, Xue CC. A Pharmacological Review of Bioactive Constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch. Phytother Res. 2016 ; 30(9) : 1445-73. DOI |
44 | Ministry Food and Drug Safety. The Korean Herbal Pharmacopoeia 4th edition. The MFDS Notification No. 2017-11. 2017 : 242-3. |
45 | Khan AL, Hussain J, Hamayun M, Gilani SA, Ahmad S, Rehman G, Kim YH, Kang SM, Lee IJ. Secondary metabolites from Inula britannica L. and their biological activities. Molecules. 2010 ; 15(3) : 1562-77. DOI |
46 | Ministry Food and Drug Safety. The Korean Pharmacopoeia 11th edition. The MFDS Notification No. 2017-21. 2017 : 94-5. |
47 | Lee YH, Lee NK, Paik HD. Antimicrobial Characterization of Inula britannica against Helicobacter pylori on Gastric Condition. J Microbiol Biotechnol. 2016 ; 26(6) : 1011-7. DOI |
48 | Asai M, Kawashima D, Katagiri K, Takeuchi R, Tohnai G, Ohtsuka K. Protective effect of a molecular chaperone inducer, paeoniflorin, on the HCl- and ethanol-triggered gastric mucosal injury. Life Sci. 2011 ; 88(7-8) : 350-7. DOI |
49 | Sharma OP, Bhat TK. DPPH antioxidant assay revisited. Food chemistry, 2009 ; 113(4) : 1202-5. DOI |
50 | Huang D, Boxin O. Prior RL. The chemistry behind antioxidant capacity assays. J. Agric. Food Chem. 2005 ; 53(6) : 1841-56. DOI |
51 | The textbook compilation committee of Korean herbology. Korean herbology. Seoul:Younglimsa. 2010 : 493, 635. |
52 | Nartey ET, Ofosuhene M, Agbale CM. Anti-ulcerogenic activity of the root bark extract of the African laburnum"Cassia sieberiana"and its effect on the anti-oxidant defence system in rats. BMC complementary and alternative medicine. 2012 ; 12(1) : 247. DOI |