Inhibition Effects on Oxidative DNA Damage and Anti-inflammatory Effects of Nelumbinis Flos
![]() |
Jeong, Hyung Jin
(Department of Medicinal Plant Resources, Andong National University)
Park, Yeon Gyeong (Department of Medicinal Plant Science, Jungwon University) Jang, Tae Won (Department of Medicinal Plant Science, Jungwon University) Kim, Do Wan (Department of Food Science and Industry, Jungwon University) Jeong, Jin Boo (Department of Medicinal Plant Resources, Andong National University) Park, Jae Ho (Department of Medicinal Plant Science, Jungwon University) |
1 | Van den Berg R, Haenen GR, Van den Berg H. Bast A. Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures. Food Chem. 1999 ; 66(4) : 511-7. DOI |
2 | Oyaizu M. Studies on products of browning reaction: antioxidative activities of products of browning reaction prepared from glucosamine. Jpn J Nutr. 1986 ; 44 : 307-15. DOI |
3 | AOAC. Official Methods of Analysis. 14th ed. Washington DC. Association of Official Analytical Chemists. 1995 ; 8-35. |
4 | Jung YJ, Surh YJ. Oxidative DNA damage and cytotoxicity induced by copper-stimulated redox cycling of salsolinol, a neurotoxic tetrahydroisoquinoline alkaloid. Free Radic Biol Med. 2001 ; 30(12) : 1407-17. DOI |
5 | Que F, Mao L, Pan X. Antioxidant activities of five Chinese rice wines and the involvement of phenolic compounds. Food Res Int. 2006 ; 39(5) : 581-7. DOI |
6 | Ferreira IC, Baptista P, Vilas-Boas M, Barros L. Free-radical scavenging capacity and reducing power of wild edible mushrooms from northeast Portugal: Individual cap and stipe activity. Food Chem. 2007 ; 100(4) : 1511-6. DOI |
7 | Yang MY, Chang YC, Chan KC, Lee YJ, Wang CJ. Flavonoid-enriched extracts from Nelumbo nucifera leaves inhibits proliferation of breast cancer in vitro and in vivo. Eur J Integr Med. 2011 ; 3 : e153-e63. DOI |
8 | Ferreres F, Gomes D, Valentano P, Goncalves R, Pio R, Chagas EA, Seabra R, Andrade P. Improved loquat (Eriobotrya japonica Lindl.) cultivars: Variation of phenolics and antioxidative potential. Food Chem. 2009 ; 114(3) : 1109-27. |
9 | Kawanishi S, Hiraku Y, Oikawa S. Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutation Res. 2001 ; 488 : 65-76. DOI |
10 | Szabo C. Role of nitric oxide in endotoxic shock. An overview of recent advances. Ann N Y Acad Sci. 1998 ; 30(851) : 422-5. |
11 | Martel-Pelletier J, Pelletier JP, Fahmi H. Cyclooxygenase-2 and prostaglandins in articular tissues. Semin Arthritis Rheum. 2003 ; 33(3) : 155-67. DOI |
12 | Weisz A, Cicatiello L, Esumi H. Regulation of the mouse inducible-type nitric oxide synthase gene promoter by interferongamma, bacterial lipopolysaccharide and NG-monomethyl-L-arginine. Biochem J. 1996 ; 316(1) : 209-15. DOI |
13 | An SM, Kim HG, Choi EJ, Hwang HH, Lee ES, Baek JH, Boo YC, Koh JS. Screening for anti-inflammatory activities in extracts from Korean herb medicines. J Soc Cosmet Scientists Korea, 2014 ; 40(1) : 95-108. DOI |
14 |
Kang CH, Choi YH, Choi IW, Lee JD, Kim GY. Inhibition of lipopolysaccharide-induced iNOS, COX-2, and TNF- |
15 | Hur GM, Ryu YS, Yun HY, Jeon BH, Kim YM, Seok JH, Lee JH. Hepatic ischemia/reperfusion in rats induces iNOS gene transcription by activation of NF-kappaB. Biochem Biophys Res Commun. 1999 ; 261(3) : 917-22. DOI |
16 | Sato T, Nakajima H, Fujio K, Mori Y. Enhancement of prostaglandin E2 production by epidermal growth factor requires the coordinate activation of cytosolic phospholipase A2 and cyclooxygenase 2 in human squamous carcinoma A431 cells. Prostaglandins. 1997 ; 53(5) : 355-69. DOI |
17 | Asensi M, Ortega A, Mena S, Feddi F, Estrela JM. Natural polyphenols in cancer therapy. Crit Rev Clin Lab Sci. 2011 ; 48 : 197-216. DOI |
18 | Huang M, Stolina M, Sharma S, Mao JT, Zhu L, Miller PW, Dubinett SM. Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages : up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res. 1998 ; 58(6) : 1208-16. |
19 | Maxwell SJ. Prospects for the use of antioxidant therapies. Drugs. 1995 ; 49 : 345-61. DOI |
20 | Marnett L. Oxiradicals and DNA damage. Carcinogenesis. 2000 ; 21 : 361-70. DOI |
21 | Shosuke K, Yusuke H, Shinji O. Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutat Res. 2001 ; 488 : 65-76. DOI |
22 | Harold ES, Darrell EA, Evan IF, John AM. A review of the interaction among dietary antioxidants and reactive oxygen species. J Nut Biochem. 2007 ; 18 : 567-79. DOI |
23 | Surh YJ. Molecular mechanism of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutation Res. 1999 ; 428(1-2) : 305-27. DOI |
24 | Choi DS. Study on the antiinflammatory effect and mechanism of isoegomaketone in vitro and in vivo. Chonbuk National University. 2009. |
25 | Johnson TM, Yu ZX, Ferrans VJ, Lowenstein RA, Finkel T. Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc Natl Acad Sci. 1996 ; 93(21) : 11848-52. DOI |
26 | Kehrer JP. Free radicals as mediators of tissue injury and disease. Crit. Rev. Toxicol. 1993 ; 23(1) : 21-48. DOI |
27 | Lawrence T, Willoughby DA, Gilroy DW. Antiinflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol. 2002 ; 2(10) : 787-95. DOI |
28 | Chae CH. Functional role of inducible nitric oxide synthase and cyclooxygenase-2 in acute inflammation. Gwacheon : Ministry of Health and Welfare. 2004 : 10-1. |
29 | Bak JP, Son JH, Kim YM, Jung JH, Leem KH, Lee EY, Kim EH. Suppression effect of the inflammatory response in macrophages by Paeoniae Radix Rubra extracts. Kor J Med Crop Sci. 2011 ; 19 : 373-9. DOI |
30 | Jung HK, Kang BM, Jang JH, Ahn BK, Yeo JH, Jung WS, Cho JH, Kuk YI, Hyun KH and Cho HW. Inhibitory effect of Alopecurus aequalis Sobol ethanol extracts on LPS-induced inflammatory response in RAW 264.7 cells. Kor J Med Crop Sci. 2014 ; 22 : 98-104. DOI |
31 | Seo BI, Lee JH, Choi HY, Kwon DR, Boo YM. Herbologycal Study on herbal medicine. Korea : Youngrim. 2008 : 761-6. |
32 | Park JH, Lee BG, Byun GI, Kim DW. Antioxidant Activities and Inhibitory Effect on Oxidative DNA Damage of Nelumbinis Semen Extracts. Kor J Herbology. 2010 ; 25(4) : 55-9. |
33 | Bondet V, Brand-Williams W, Berset C. Kinetics and mechanisms of antioxidant activity using the DPPH free radical method. LWT - Food Sci Technol. 1997 ; 30(6) : 609-15. DOI |
![]() |