Browse > Article
http://dx.doi.org/10.6116/kjh.2015.30.4.29.

Antibacterial and Antioxidant activities of Bio-fermented Sanguisorbae Radix Extract  

Kil, Ki-Jung (Department of Herbal pharmaceutical Science, Joongbu University)
Doh, Eun-Soo (Department of Herbal pharmaceutical Science, Joongbu University)
Chang, Jun-Pok (Department of Herbal pharmaceutical Science, Joongbu University)
Lee, Seung-Hyun (Liberal Arts School, Jungwon University)
Yoo, Ji-Hyun (Department of Herbal pharmaceutical Science, Joongbu University)
Publication Information
The Korea Journal of Herbology / v.30, no.4, 2015 , pp. 29-35 More about this Journal
Abstract
Objectives : The objective of this research was to investigate the antibacterial and antioxidant activities of bio-fermented Sanguisorbae Radix extract.Methods : The Sanguisorbae Radix extract was fermented byStreptococcus thermophilus,and their products was tested for antibacterial activity against pathogenic microorganisms namely,Bacillus cereus,Bacillus subtilis,Staphylococcus aureus,Escherichia coli,Vibrio parahaemolyticusandSalmonella typhimuriumby paper disc diffusion method and the antioxidant activities of extract was evaluated by five different assays as electron donating ability(EDA), superoxide dismutase(SOD)-like activity, polyphenol, flavonoid contents and nitrite scavenging ability.Results : The bio-fermented Sanguisorbae Radix extract was safe from heat. Antibacterial activity of fermented Sanguisorbae Radix extract appeared relatively highly againstBacillus cereusandStaphylococcus aureusand didn't show any difference. EDA in comparison to Vitamin C showed over 90% activity at about the same time of Sanguisorbae Radix extract expressed highly. SOD activity showed 15% in fermentation before and after. The nitrite scavenging ability of Sanguisorbae Radix extract before and after fermentation showed higher numerical value over 70% in pH 2.5 than that of butylated hydroxytoluene(BHT). But SOD activity, EDA and nitrite scavenging ability were not different between the Sanguisorbae Radix extract before and after fermentation. Total polyphenol content expressed over about 20 mg/g, and that of the Sanguisorbae Radix extracts was increased than that of the fermented Sanguisorbae Radix extracts.Conclusions : The results suggest the usefulness of developing functional materials using antioxidant active Sanguisorbae Radix extract was fermented bySalmonella typhimuriumwith high polyphenol contents and nitrite scavenging ability.
Keywords
Fermention; Sanguisorbae Radix; Antibacterial; Antioxidant;
Citations & Related Records
Times Cited By KSCI : 5  (Citation Analysis)
연도 인용수 순위
1 Moreno MI, Isla MI, Sampietro AR, Vattuone MA. Comparision of the free radical-scavenging activity of propolis from several regions of Argentina. J Ethnopahrmacol. 2000 ; 71 : 109-14.   DOI   ScienceOn
2 Kato H, Lee IE, Chuyen NV, Kim SB, Hayase F. Inhibition of nitrosamine formation by nondialyzable melanoidines. Agric Biol Chem. 1987 ; 51 : 1333-8.   DOI
3 Technology Trends Survey Report. Environment/energy sector. The 4th technology of food fermentation. Korean Intellectual Property Office. 2001.
4 Wang YC, Yu RC, Chou CC. Antioxidative activityes of soymilk fermented with lactic acid bacteria and bifidobacteria. Food Microbiol. 2006 ; 23 : 128-35.   DOI   ScienceOn
5 Choi OJ, Rhee HJ, Choi KH. Antimicrobial activity of korean wild tea extract according to the degree of fermentation. J Korean Soc Food Sci Nutr. 2005 ; 34 : 148-57.   DOI   ScienceOn
6 Jeon YH, Kim MH, Kim MR. Antioxidative and antimutagenic activity of ethanol extracts from Cuscutae semen. Korean J Food Cookery Sci. 2008 ; 24 : 46-51.
7 Kim EY, Baik IH, Kim JH, Kim SR, Rhyu MR. Screening of the antioxidant activity of some medicinal plants. Korean J Food Sci Technol. 2004 ; 36 : 333-8.
8 Park J, Lee J, Jun W. Radical scavenging and anti-obesity effects of various extracts from turmeric (Curcuma linga L.). J Korean Soc Food Sci Nutr. 2013 ; 42 : 1908-14.   DOI   ScienceOn
9 Rhim TJ. In vitro Antioxidant Activity of Sanguisorbae Radix Ethanol Extracts. Korean J Plant Resour. 2013 ; 26 : 149-58.   DOI   ScienceOn
10 An BJ, Lee SA, Son JH, Kwak JH, Park JM, Lee JY. Cytotoxic and antibacterial activities of Sanguisorbae officinalis L. J Korean Soc Appl Biol Chem. 2004 ; 47 : 141-5.
11 Kim TG, Kang SY, Jung KK, Kang JH, Lee E, Han HM, Kim SH. Antiviral activities of extracts isolated from Terminalis chebula Retz., Sanguisorba officinalis L., Rubus coreanus Miq. and Rheum palmatum L. against hepatitis B virus. Phytother Res. 2001 ; 15 : 718-20.   DOI   ScienceOn
12 Jeong CS, Suh IO, Hyun JE, Lee EB. Screening of hepatoprotective activity of medicinal plant extracts on carbon tetrachloride-induced hepatotoxicity in rats. Nat Prod Sci. 2003 ; 9 : 87-90.
13 Swain T, Hillis WE, Ortega M. Phenolic constituents of Ptunus domestica. I. Quantitative analysis of phenolic constituents. Sci Food Agric. 1959 ; 10 : 83-8.   DOI
14 Nguyen TT, Cho SO, Ban JY, Kim JY, Ju HS, Koh SB, Song KS, Seong YH. Neuroprotective effect of Sanguisorbae radix against oxidative stress-induced brain damage: in vitro and in vivo. Biol Pharm Bull. 2008 ; 31 : 2028-35.   DOI   ScienceOn
15 An RB, Tian YH, Oh H, Kim YC. In vitro free radical scavenging and hepatoprotective compound from Sanguisorbae radix. Nat Prod Sci. 2005 ; 11 : 119-22.
16 An BJ, Lee JT, Lee SA, Kwak JH, Park JM, Lee JY, Son JH. Antioxidant effects and application as natural ingredients of Korean Sanguisorbae officinalis L. J Korean Soc Appl Biol Chem. 2004 ; 47 : 244-50.
17 Simic MG. Mechanisms of inhibition of free radical processed in mutagenesis and carcinogenesis. Mutat Res. 1988 ; 202 : 386-99.   DOI   ScienceOn
18 Marklund S, Marklunrl G. Involvement of superoxide anion radical in the oxidation of pyrogallol and a cinvenient assay for superoxide dismutase. Eur J Biochem. 1974 ; 47 : 468-74.   DOI   ScienceOn
19 Blois MS. Antioxidant determination by the use of a stable free radical. Nature. 1958 ; 181 : 1199.   DOI   ScienceOn
20 Yoon SO, Yoo SJ, Oh S. A Study on the phamacological and nutritional values of needles of Pinus densiflora S. Res Bull Exp For. 1997 ; 5 : 63-81.
21 Lin MY, Yen CL. Inhibition of lipid peroxidation by Lactobacillus acidophillus and Bifidobacterium longum. J Agric Food Chem. 1999 ; 47 : 3661-4.   DOI   ScienceOn
22 Ito M, Ohishi K, Yoshida Y, Yokoi W, Sawada H. Antioxidative effects of lactic and bacteria on the colonic mucosa of iron-overloaded mice. J Agric Food Chem. 2003 ; 51 : 4456-60.   DOI   ScienceOn
23 Cherry JP. Improving the safety of fresh produce with antimicrobials. food Technol. 1999 ; 53 : 54-9.
24 Davidson PM, Post LS. Naturally occurring and miscellaneous food antimicrobials. In Antimicrobials in foods. In Branen AL. Davidson PM(eds.). New York : Marcel Dekken Inc. 1983 : 371.
25 Lewis RJ. There regulatory status their use by the food industry. In Food additives handbook. In Robert WD(ed.). New York : Nostrand Reinhold. 1989 : 3-27.
26 Kim HJ, Ahn MS, Kim GH, Kang MH. Antioxidant and antimicrobial activity of Pleurotus eryngii extracts prepared from different aerial part. Korean J Food Sci Technol. 2006 ; 39 : 799-804.
27 Nam SH, Kang MY. Screening of antioxidative activity of hot water extracts from medicinal plants. J Korean Soc Agric Chem Biotechnol. 2000 ; 43 : 141-7.
28 Ames BN, Shigenaga MK, Hagen TM. Oxidants antioxidants and the degenerative disease of aging. Proc Natl Acad Sci USA. 1983 ; 90 : 7915-22.   DOI
29 Ryu JH, Park YJ, Kim HS. Antibacterial Activity of Fermented Korean Medicine Against Multi-drug Resistant Pseudomonas aeruginosa. Korean Soc Biotechnol Bioengineering J. 2011 ; 26 : 543-51.
30 Akaike T, Ijiri S, Sato J, Katsiki T, Maeda H. Determination of peroxyl radical scavenging activity in food by using bactericidal action of alkyl peroxyl radical. J Agric Food Chem. 1995 ; 43 : 1864-70.   DOI   ScienceOn
31 Namiki MO. Antioxidants and antimutagens in food. Crit Rev Food Sci. 1990 ; 29 : 273-300.   DOI   ScienceOn
32 Frankel EN, Huang SW, Aeschbach R, Prior E. Antioxidant activity of rosemary extract and its constituents, carnosic acid, carnosol, and rosmarinic acid, in bulk oil and oil-in water emulsion. J Agric Food Chem. 1996 ; 44 : 131–5.   DOI   ScienceOn
33 Rein D, Paglieroni TG, Wun T, Oearson DA, Schmitz HH, Gosselin R, Keen CL. Cocoa inhibits platelet activation and function. Am J Clin Nutr. 2000 ; 72 : 30-5.
34 Giese J. Antioxidants: tools for preventing lipid oxidation. Food Technol. 1996 ; 50 : 73–80.
35 Rice-Evans CA, Miller HJ, Oaganga G. Structure antioxidant activity relationships of flavonoids and phenolic acids. Free Rad Biol Med. 1996 ; 20 : 933-56.   DOI   ScienceOn
36 Azuma K, Nakayama M, Koshika M, Lpoushi K, Yamaguchi Y, Kohata K, Ito H, Higashio H. Phenolic antioxidants from the leaves of Corchorus olitorius L. J Agric Food Chem. 1999 ; 47 : 3963-6.   DOI   ScienceOn
37 Wursch P. Influence of tannin-rich carob pod fiber on the cholestrol metabolism in the rat. J Ntur. 1979 ; 109 : 685-92.
38 Hatano T. Constituents of natural medicines with scavenging effects on active oxygen species tannins and related polyphenols. Nat Med. 1995 ; 49 : 357-63.
39 Shin DH. The Study course and movement of natural antioxidants. Kor Food Sci Tech. 1997 ; 30 : 14-8.
40 Compilation Committee of Korea Herbology. Herbology. Seoul : Younglimsa. 2007 : 434-5.
41 Pratt DE. Natural antioxidants from plant materials. In Phenolic Compounds in Food and Their Effects on Health (II). Huang MT, Hl ST, Lee CY, eds. Washington DC : Am Chem Soc. 1992 : 54-60.