Effect of Tetramethylpyrazine on Pro-Inflammatory Cytokine Expressions in Mouse Brain Tissue following Intracerebroventricular Lipopolysaccharide Treatment |
Choi, Yong-Seok
(Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University)
Won, Jong-Woo (Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University) Yoo, Inwoo (Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University) Shin, Jung-Won (Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University) Kim, Seong-Joon (Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University) Sohn, Nak-Won (Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University) |
1 | Cai D, Liu T. Hypothalamic inflammation: a double-edged sword to nutritional diseases. Ann NY Acad Sci. 2011 ; 1243 : E1-39. DOI ScienceOn |
2 | Granger JI, Ratti PL, Datta SC, Raymond RM, Opp MR. Sepsis-induced morbidity in mice: Effects on body temperature, body weight, cage activity, social behavior and cytokines in brain. Psychoneuroendocrinology. 2012 ; doi :10.1016/j.psyneuen.2012.10.010. DOI ScienceOn |
3 | Harden LM, du Plessis I, Roth J, Loram LC, Poole S, Laburn HP. Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL- and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior. Psychoneuroendocrinology. 2011 ; 36 : 608-22. DOI ScienceOn |
4 | Mancuso C, Navarra P, Preziosi P. Roles of nitric oxide, carbon monoxide, and hydrogen sulfide in the regulation of the hypothalamic-pituitary-adrenal axis. J Neurochem. 2010 ; 113 : 563-75. DOI ScienceOn |
5 | Grinevich V, Ma XM, Herman JP, Jezova D, Akmayev I, Aguilera G. Effect of repeated lipopolysaccharide administration on tissue cytokine expression and hypothalamic-pituitary-adrenal axis activity in rats. J Neuroendocrinol. 2001 ; 13 : 711-23. DOI ScienceOn |
6 | Kim HC. Herbal Pharmacology. Seoul Gipmoon-Dang. 2001 : 318-20. |
7 | Choi SH, Aid S, Bosetti F. The distinct roles of cyclooxygenase-1 and –2 in neuroinflammation: implications for translational research. Trends Pharmacol Sci. 2009 ; 30 : 174-81. DOI ScienceOn |
8 | Zheng CY, Xiao W, Zhu MX, Pan XJ, Yang ZH, Zhou SY. Inhibition of cyclooxygenase-2 by tetramethylpyrazine and its effects on A549 cell invasion and metastasis. Int J Oncol. 2012 ; 40 : 2029-37. |
9 | He X, Zheng Z, Yang X, Lu Y, Chen N, Chen W. Tetramethylpyrazine attenuates PPAR- antagonist-deteriorated oxazolone-induced colitis in mice. Mol Med Report. 2012 ; 5 : 645-50. |
10 | Liang SD, Gao Y, Xu CS, Xu BH, Mu SN. Effect of tetramethylpyrazine on acute nociception mediated by signaling of P2X receptor activation in rat. Brain Res. 2004 ; 995 : 247-52. DOI ScienceOn |
11 | Li SY, Jia YH, Sun WG, Tang Y, An GS, Ni JH, Jia HT.Stabilization of mitochondrial function by tetramethylpyrazine protects against kainateinduced oxidative lesions in the rat hippocampus. Free Radic Biol Med. 2010 ; 48 : 597-608. DOI ScienceOn |
12 | Sternberg EM. Neural-immune interactions in health and disease. J Clin Invest. 1997 ; 100 : 2641–7. DOI ScienceOn |
13 | Rosenberg PB. Clinical aspects of inflammation in Alzheimer's disease. Int Rev Psychiatry. 2005 ; 17 : 503-14. DOI ScienceOn |
14 | Shih YH, Wu SL, Chiou WF, Ku HH, Ko TL, Fu YS. Protective effects of tetramethylpyrazine on kainate-induced excitotoxicity in hippocampal culture. Neuroreport. 2002 ; 13 : 515-9. DOI ScienceOn |
15 | Zhang Z, Wei T, Hou J, Li G, Yu S, Xin W.Iron-induced oxidative damage and apoptosis in cerebellar granule cells: attenuation by tetramethylpyrazine and ferulic acid. Eur J Pharmacol. 2003 ; 467 : 41-7. DOI ScienceOn |
16 | Cheng XR, Zhang L, Hu JJ, Sun L, Du GH. Neuroprotective effects of tetramethylpyrazine on hydrogen peroxide-induced apoptosis in PC12 cells. Cell Biol Int. 2007 ; 31 : 438-43. DOI ScienceOn |
17 | Liao SL, Kao TK, Chen WY, Lin YS, Chen SY, Raung SL, Wu CW, Lu HC, Chen CJ. Tetramethylpyrazine reduces ischemic brain injury in rats. Neurosci Lett. 2004 ; 372 : 40-5. DOI ScienceOn |
18 | Kao TK, Ou YC, Kuo JS, Chen WY, Liao SL, Wu CW, Chen CJ, Ling NN, Zhang YH, Peng WH. Neuroprotection by tetramethylpyrazine against ischemic brain injury in rats. Neurochem Int. 2006 ; 48 : 166-76. DOI ScienceOn |
19 | Szelenyi J. Cytokines and the central nervous system. Brain Res Bull. 2001 ; 54 : 329-38. DOI ScienceOn |
20 | Banks WA, Kastin AJ. Relative contributions of peripheral and central sources to levels of IL-1 alpha in the cerebral cortex of mice: Assessment with species-specific enzyme immunoassays. J Neuroimmunol. 1997 ; 79 : 22-8. DOI ScienceOn |
21 | Hsiao G, Chen YC, Lin JH, Lin KH, Chou DS, Lin CH, Sheu JR. Inhibitory mechanisms of tetramethylpyrazine in middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia in rats. Planta Med. 2006 ; 72 : 411-7. DOI ScienceOn |
22 | Yang J, Li J, Lu J, Zhang Y, Zhu Z, Wan H. Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia. J Ethnopharmacol. 2012 ; 140 : 64-72. DOI ScienceOn |
23 | Chang Y, Hsiao G, Chen SH, Chen YC, Lin JH, Lin KH, Chou DS, Sheu JR. Tetramethylpyrazine suppresses HIF-1alpha, TNF-alpha, and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats. Acta Pharmacol Sin. 2007 ; 28 : 327-33. DOI ScienceOn |
24 | Zhu XL, Xiong LZ, Wang Q, Liu ZG, Ma X, Zhu ZH, Hu S, Gong G, Chen SY. Therapeutic time window and mechanism of tetramethylpyrazine on transient focal cerebral ischemia/ reperfusion injury in rats. Neurosci Lett. 2009 ; 449 : 24-7. DOI ScienceOn |
25 | Xiao X, Liu Y, Qi C, Qiu F, Chen X, Zhang J, Yang P. Neuroprotection and enhanced neurogenesis by tetramethylpyrazine in adult rat brain after focal ischemia. Neurol Res. 2010 ; 32 : 547-55. DOI ScienceOn |
26 | Sun Y, Yu P, Zhang G, Wang L, Zhong H, Zhai Z, Wang L, Wang Y. Therapeutic effects of tetramethylpyrazine nitrone in rat ischemic stroke models. J Neurosci Res. 2012 ; 90 : 1662-9. DOI ScienceOn |
27 | Tang Q, Han R, Xiao H, Shen J, Luo Q, Li J. Neuroprotective effects of tanshinone IIA and/or tetramethylpyrazine in cerebral ischemic injury in vivo and in vitro. Brain Res. 2012 ; 1488 : 81-91. DOI ScienceOn |
28 | Gao C, Liu X, Liu W, Shi H, Zhao Z, Chen H, Zhao S. Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following subarachnoid hemorrhage in rats. Auton Neurosci. 2008 ; 141 : 22-30. DOI ScienceOn |
29 | Fan LH, Wang KZ, Cheng B, Wang CS, Dang XQ. Anti-apoptotic and neuroprotective effects of Tetramethylpyrazine following spinal cord ischemia in rabbits. BMC Neurosci. 2006 ; 7 : 48. DOI |
30 | Liang Y, Yang QH, Yu XD, Jiang DM. Additive effect of tetramethylpyrazine and deferoxamine in the treatment of spinal cord injury caused by aortic cross-clamping in rats. Spinal Cord. 2011 ; 49 : 302-6. DOI ScienceOn |
31 | Fan L, Wang K, Shi Z, Die J, Wang C, Dang X. Tetramethyl- pyrazine protects spinal cord and reduces inflammation in a rat model of spinal cord ischemia-reperfusion injury. J Vasc Surg. 2011 ; 54 : 192-200. DOI ScienceOn |
32 | Hu JZ, Huang JH, Xiao ZM, Li JH, Li XM, Lu HB. Tetramethyl- pyrazine accelerates the function recovery of traumatic spinal cord in rat model by attenuating inflammation. J Neurol Sci. 2013 ; 324 : 94-9. DOI ScienceOn |
33 | Fu X, Zunich SM, O'Connor JC, Kavelaars A, Dantzer R, Kelley KW. Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures. J Neuroinflammation. 2010 ; 7 : 43. DOI ScienceOn |
34 | Harry GJ, Kraft AD. Neuroinflammation and microglia: considerations and approaches for neurotoxicity assessment. Expert Opin Drug Metab Toxicol. 2008 ; 4 : 1265-77. DOI ScienceOn |
35 | Konat GW, Kielian T, Marriott I. The role of Toll-like receptors in CNS response to microbial challenge. J Neurochem. 2006 ; 99 : 1–12. |
36 | Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia. 2007 ; 55 : 453-62. DOI ScienceOn |
37 | Jeong HK, Jou I, Joe EH. Systemic LPS administration induces brain inflammation but not dopaminergic neuronal death in the substantia nigra. Exp Mol Med. 2010 ; 42 : 823-32. DOI ScienceOn |