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http://dx.doi.org/10.6116/kjh.2012.27.5.65

Cosmeceutical Activities of Doinseunguitang and Its Composition  

Lee, Jin-Young (Department of Herbal Cosmetic Science, Hoseo University)
Lee, Soo-Yeon (Department of Herbal Cosmetic Science, Hoseo University)
Jun, Hye-Ji (Department of Herbal Cosmetic Science, Hoseo University)
Yoon, Ji-Young (Department of Herbal Cosmetic Science, Hoseo University)
Hwang, Hyun-Uk (Department of Herbal Cosmetic Science, Hoseo University)
Park, Joo-Hoon (Department of Herbal Cosmetic Science, Hoseo University)
An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University)
Son, Jun-Ho (Korea Promotion Institute for Traditional Medicine Industry)
Hwang, Ju-Young (Korea Promotion Institute for Traditional Medicine Industry)
Publication Information
The Korea Journal of Herbology / v.27, no.5, 2012 , pp. 65-75 More about this Journal
Abstract
Objectives : Cosmeceutical activities such as anti-oxidative and anti-aging effects of the Doinseunguitang and its composition, a traditional prescription, were evaluated. Methods : We performed MTT assay, melanin synthesis inhibition assay, DPPH free radical scavenging assay, SOD-like activity, xanthine oxidase inhibition assay, astringent activity assay, tyrosinase inhibition assay, elastase and collagenase inhibition assay. Results : The results were obtained as follows : DPPH free radical scavenging of water extract Doinseunguitang (DISG) and ethanol extract DISG was 60% and 50% at 1,000 ppm. Xanthine oxidase inhibition effect of ethanol extract showed more than 80% at 500 ppm. Tyrosinase inhibition and inhibition melanin synthesis activities were measured in 40% and 50% at 1,000 ppm and 100 ppm. Elastase and collagenase inhibition rate of ethanol extracts DISG 40% and 80% at 1,000 ppm. It was concluded that compositive ingredients (Persicae Seman, Glycyrrhizae Radix, Cinnamomi Ramulus, Rhei Rhizoma) influenced the most results. Conclusions : The results indicated that, ethanol extract which is superior in its anti-oxidative and anti-aging effects is useful to be applied in herbal cosmetic industry.
Keywords
Doinseunguitang; anti-oxidant; anti-aging; herbal cosmetic; compositive ingredients;
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