Browse > Article
http://dx.doi.org/10.6116/kjh.2012.27.3.15

Comparative Study on Different Species of Medicinal Herbs Used as Jeonho (Qianhu) Using Morphological Appearance and Chromatographic Fingerprint  

Kim, Jung-Hoon (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine)
Lee, Guem-San (Department of Herbology, Wonkwang University)
Choi, Go-Ya (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine)
Kim, Young-Sik (Department of Herbology, Woosuk University)
Lee, Seung-Ho (Department of Herbology, Woosuk University)
Kim, Hong-Jun (Department of Herbology, Woosuk University)
Jeong, Seung-Il (Jeonju Biomaterials Institute)
Ju, Young-Sung (Department of Herbology, Woosuk University)
Publication Information
The Korea Journal of Herbology / v.27, no.3, 2012 , pp. 15-21 More about this Journal
Abstract
Objective : This study aimed to compare the difference between $Angelica$ $decursiva$, Peucedanum $praeruptorum$ and $Anthriscus$ $sylvestris$ which have been used as herbal medicine, Jeonho (Angelicae Decursivae Radix) in Korea and provided the evidence to exclude $A.$ $sylvestris$ not to use as Joenho. Methods : The similarities of original medicinal herb with samples from local market were evaluated including morphological appearance and chromatographic fingerprint. In addition, relation between original medicinal herb and local samples were analyzed using statistical clustering methods. Results : $A.$ $decursiva$, $P.$ $praeruptorum$ and $A.$ $sylvestris$ represented different morphological appearances and chromatographic fingerprint. Several samples from China exhibited similar morphological and chromatographic appearance with $A.$ $decursiva$ or $P.$ $praeruptorum$. Eleven samples from Korea showed identical similarity to $A.$ $sylvestris$. Conclusions : Since $A.$ $sylvestris$ represented obvious differences compared to $A.$ $decursiva$ and $P.$ $praeruptorum$, it is required not to use $A.$ $sylvestris$ as medicinal herb, Jeonho. Additionally, exact identification and quality control must be applied to $A.$ $decursiva$ or $P.$ $praeruptorum$ from China in order to maintain therapeutical efficacy.
Keywords
Angelica decursiva; Peucedanum praeruptorum; Anthriscus sylvestris; similarity; morphological apprearance; chromatographic fingerprint;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Hemalatha S, Ghafoorunissa. Lignans and tocopherols in Indian sesame cultivars. J Am Oil Chem Soc. 2004 ; 81(5) : 467-70.   DOI   ScienceOn
2 Korea Food and Drug Administration. The Korean Herbal Pharmacopeia. KFDA's Notification No. 2011-26.
3 The Chinese Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China 2010. Beijing : China Medical Science and Technology Press. 2010 ; 248-317.
4 Ministry of Health, Labour and Welfare. The Japanese Pharmacopoeia Sixteenth Edition. Notification No. 65. Retrieved Mar 12 2012, available from :http://jpdb.nihs.go.jp/jp16/YAKKYOKUHOU16.pdf.
5 Lee GS. Identification key of Jeonho (Qianhu) and its adulterants. Department of Korean Medicine Science. School of Korean Medicine. Pusan National University. 2011.
6 Chen Y, Yan Y, Xie MY, Nie SP, Liu W, Gong XF, Wang YX. Development of a chromatographic fingerprint for the chloroform extracts of Ganoderma lucidum by HPLC and LC-MS. J Pharm Biomed Anal. 2008 ; 47 : 469-77.   DOI   ScienceOn
7 Ding Y, Xiang LY, Zhang T, Ji S, Xu LY. Chemical fingerprint analysis of Gardenia jasminoides fruit by high-performance liquid chromatography. Journal of Food and Drug Analysis. 2010 ; 18(3) : 180-90.
8 Korea Food and Drug Administration. Guideline for chemical profiling of herbal medicinal product [Internet]. Retrieved Sep 10 2011, available from : .http://www.kfda.go.kr/index.kfda?mid=102&cd=&cmd=v&seq=11633.
9 Goodwin RH, Pollock BM. Ultraviolet absorption spectra of coumarin derivatives[Internet]. 1954. Retrieved Nov 10 2011, available from : http://bio.classes.ucsc.edu/bio100l/EXERCISES/SPE CTROPHOTOMETRY/Goodwin%20and%20Pollock%20 1954.pdf.