Mountain cultivated ginseng water boiled extract decreases blood glucose level and improves lipid metabolism in male db/db mice
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Kim, Eung-Lae
(Woori Institute of Mountain Cultivated Ginseng)
Kim, Chang-Sik (Woori Institute of Mountain Cultivated Ginseng) Lee, Hee-Young (Dept. of Formula Science, College of Oriental Medicine & Research Institute of Oriental Medicine, Dong-Eui University) Lee, Hye-Rim (Dept. of Formula Science, College of Oriental Medicine & Research Institute of Oriental Medicine, Dong-Eui University) Kim, Eung-Yeol (Kongju Communication Arts University) Yoon, Mi-Chung (Dept. of Life Sciences, Mok-Won University) Shin, Soon-Shik (Dept. of Formula Science, College of Oriental Medicine & Research Institute of Oriental Medicine, Dong-Eui University) |
1 | Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339( 4):229-234. DOI ScienceOn |
2 | Ie Byung Park. Diabetes Dyslipidemia:Causes and Consequences. Korean Clinical Diabetes J 2010; 11:107-109. |
3 | Goldberg IJ. Clinical review 124: Diabetic dyslipidemia:causes and consequences. J Clin Endocrinol Metab. 2001;86(3):965-971. DOI |
4 | American Diabetes Association. Standards of medical care in diabetes-2010. Diabetes Care. 2010;33 Suppl 1:S11-61. |
5 | Syvanne M, Taskinen MR. Lipids and lipoproteins as coronary risk factors in non-insulin-dependent diabetes mellitus. Lancet. 1997;350 Suppl 1: SI20-3. |
6 | Jeong-Du Roh, Lak-Hyung Kim, Beom-Yong Song, Tae-Han Yook. The Effects of distilled Wild Ginseng Herbal Acupuncture on the Heart Rate Variability(HRV). The Journal of Korean Pharmacopuncture Institute 2008;11(1):55-69. |
7 | Tae-Jin Rhim, Hee-Sun Jeong, Young-Jin Kim, Doo-Yong Kim, Young-Ju Han, Hye-Yon Kwon, Ki-Rok Kwon. A study on the comparison of antioxidant effects among cultivated ginseng, and cultivated wild ginseng extracts -Using the measurement of superoxide and hydroxy radical scavenging activities-. The Journal of Korean Pharmacopuncture Institute 2009;12(2):7-12. DOI |
8 | Dong-Hee Lee, Ki-Rok Kwon. Analysis of Serum Proteom after Intravenous Injection of cultivated wild ginseng pharmacopuncture. The Journal of Korean Pharmacopuncture Institute 2006;9(2): 17-37. DOI |
9 | Byoung-Woo Kim, Ki-Rok Kwon. The Effect of Cultivated Wild Ginseng Extract on Preadipocyte Proliferation. The Journal of Korean Pharmacopuncture Institute 2007;10(3):29-35. DOI |
10 | Young-Jin Kim, Do-Il Park, Ki-Rok Kwon. Case report on the Improvement of Liver Functions by Mountain Cultivated Wild Ginseng Pharmacopuncture. The Journal of Korean Pharmacopuncture Institute 2009;12(2):107-112. DOI |
11 | Young-Jin Ryu, Kwang-Ho Lee, Ki-Rok Kwon, Yeon-Hee Lee, Joong-Cheol Ahn, Seung-Ho Sun, Sun-Ju Lee. Mountain Ginseng Pharmacopuncture Treatment on Three Amyotrophic Lateral Sclerosis Patients-Case Report-. The Journal of Korean Pharmacopuncture Institute 2010;13(4):119-128. DOI |
12 | Byung-Jun Cho, Ki-Rok Kwon. Proposal of Self Targeting Therapy of Mountain Ginseng Pharmacopuncture. The Journal of Korean Pharmacopuncture Institute 2011;14(2):75-80. DOI |
13 | Korean Diabetes Association. Diabetes. 3rd ed. Seoul: Korean Diabetes Association, 2005: 443-450. |
14 | Kannel WB, McGee DL. Diabetes and cardiovascular disease: The Framingham study. JAMA 1979;241(19):2035-2038. DOI ScienceOn |
15 | Kwon Ki Rok. Anticancer effect of mountain ginseng Pharmacopuncture to the nude mouse of lung carcinoma induced by NCI-H460 human non-small cell lung cancer cells. The Journal of Korean Pharmacopuncture Institute 2010;13(1): 5-14. |
16 | Gu K, Cowie CC, Harris MI. Diabetes and decline in heart disease mortality in US adults. JAMA 1999;281(14):1291-1297. DOI ScienceOn |
17 | Ki-Rok Kwon, A-La Cho, Sun-Gu Lee. The Study on Acute and Subacute Toxicity and Anti-cancer Effects of cultivated wild ginseng Herbal acupuncture. The Journal of Korean Pharmacopuncture Institute 2003;6(2):7-27. |
18 | Byung-Il Min, Ho-Hyun Kim, Il-Bok Seo, Ki-Rok Kwon. Antitumor Effects and Protective Effects Against Doxorubicin-induced Testicular Toxicity of Cultivated Wild Ginseng Extract in the B16/F10 Melanoma-Bearing C57BL/6Mice. The Journal of Korean Pharmacopuncture Institute 2007;10(1): 85-100. |
19 | Jang SB, Lim CS, Jang JH, Kwon KR. Anti-metastatic mechanism of mountain cultivated wild ginseng in human cancer cell line. The Journal of Korean Pharmacopuncture Institute 2010;13(1):37-43. DOI |
20 | Hee-Chul Cho, Sun-Gu Lee, Ki-Rok Kwon. An Experimental Study on Apoptosis of cultivated Wild Ginseng Distilled Herbal Acupuncture by Concentration Level. The Journal of Korean Pharmacopuncture Institute 2004;7(2):5-17. |
21 | Won-Pil Park, Ki-Rok Kwon, Eun Lee. Effects of distilled Cultivated Wild Ginseng Herbal Acupuncture in Rats with Diabetes Induced by High Fat Diet. The Journal of Korean Pharmacopuncture Institute 2005;8(2):97-108. DOI |
22 | Eun-Ju Choi, Joon-Moo Lee, Seung-Hwan Won, Ki-Rok Kwon. Effects of cultivated wild ginseng pharmacopuncture on lowering lipid and oxidative capacity in biochemical and molecular biological study in obese rats. The Journal of Korean Pharmacopuncture Institute 2006;9(1):5-20. |
23 | Behar S, Boyko V, Reicher-Reiss H, Goldbourt U. Ten-year survival after acute myocardial infarction: comparison of patients with and without diabetes. Am Heart J. 1997;133(3):290-6. DOI ScienceOn |
24 | Hae-Young Jang, Hee-Soo Park, Ki-Rok Kwon, Tae-Jin Rhim. A study on the comparison of antioxidant effects among wild ginseng, cultivated wild ginseng, and cultivated ginseng extracts. The Journal of Korean Pharmacopuncture Institute 2008;11(3):67-78. DOI |
25 | http://kostat.go.kr (Statistics Korea) |
26 | Korea Centers for Disease Control and Prevention Division of Health and Nutrition Survey. Korea Health Statistics 2010:Korea National Health and Nutrition Examination Survey (KNHANES V-1). Division of Health Policy, Bureau of Health Policy, Ministry of Health and Welfare, 2011:56-57. |
27 | Shin Soon Shik, Kim Kyeong Cheol, Choi Yung Hyun, Lee Yong Tae, Eom Hyun Sup, Kim Chang Shik. Critic Standardization and Objectivity of Mountain Grown Ginseng. Journal of Dong-Eui Oriental Medicine 2001;5:108-112. |
28 | Shen Wei Tang(唐愼微) Original Author; Shang ZJ․ Zheng JS․Shang YO․Liu DP Interpreters. "Classified Emergency Materia Medica(證類本草)". First Edition. Beijing: Hua Xia Publishing House, 1993: 149-150. |
29 | Soon Shik Shin, Gyeong Cheol Kim, Chang Shik Kim. Sansam of South Korea. Korean J. Oriental Physiology & Pathology 2002;16(6):1260-1262. |
30 | Jun Mo Wang, Heng Fen Wang editor. "revised Shennong's Classic of Materia Medica (神農本草經校 證)". First Edition. Changchun: Jilin Science and Technology Press, 1988:151. |
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