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http://dx.doi.org/10.7181/acfs.2019.00633

Primary amelanotic melanoma of the mandibular gingiva  

Kim, Byeong Jun (Pop Plastic Surgery Clinic)
Kim, Hyeong Seop (Department of Plastic and Reconstructive Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine)
Chang, Yong Joon (Department of Plastic and Reconstructive Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine)
Kwon, Kee Hwan (Department of Otolaryngology-Head and Neck Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine)
Cho, Seong Jin (Department of Pathology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine)
Publication Information
Archives of Craniofacial Surgery / v.21, no.2, 2020 , pp. 132-136 More about this Journal
Abstract
Oral mucosal melanoma is a very rare type of malignant melanoma, the characteristics of which differ from those of cutaneous melanoma. Primary amelanotic melanoma of the mandibular gingiva, which can invade the mandibular bone, is very rare worldwide. Here, we report a case in which we performed a reconstruction of the mandible and gingiva using the fibula osteocutaneous free flap procedure to treat a patient diagnosed with a primary amelanotic melanoma of the mandibular gingiva. The procedure was successful, and no recurrence was observed 10 months after surgery. Oral mucosal melanoma has a much poorer prognosis and a lower 5-year survival rate than cutaneous melanoma. However, recently, immunomodulatory therapies for mutations in melanocytic lesions have been used effectively to treat the increasing number of patients developing this type of melanoma, thus improving the prognosis of patients with oral mucosal melanoma.
Keywords
Amelanotic; Mandible; Melanoma; Mouth mucosa;
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