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http://dx.doi.org/10.13066/kspm.2021.16.3.15

Effect of Acute Phase Pain Control Using TENS on Pain Relief in Knee Osteoarthritis in a Rat Model  

Chen, Chang-Da (Department of Rehabilitation Sciences, Graduate School, Daegu University)
Kim, Seung-Kyu (Department of Rehabilitation Sciences, Graduate School, Daegu University)
HwangBo, Gak (Department of Physical Therapy, College of Rehabilitation Sciences, Daegu University)
Publication Information
Journal of the Korean Society of Physical Medicine / v.16, no.3, 2021 , pp. 15-20 More about this Journal
Abstract
PURPOSE: This study examined the influence of treadmill exercise with initial pain control using transcutaneous electrical nerve stimulation (TENS) on induced pain of knee osteoarthritis in rats. METHODS: Thirty adult male Sprague - Dawley rats were divided randomly into the TENS Group (TG, n = 10), Treadmill Exercise Group (TEG, n = 10), and Treadmill with TENS Group (TTG, n = 10). In the TG, TENS was performed for 20 min per day for two weeks with a TENS program at the knee joint. The TEG performed treadmill exercise 15 m/min for 20 min per day for two weeks. The TTG performed initial pain control by TENS program during the 1st ~ 3rd days, and treadmill exercise was performed using the TEG methods from the 4th day. The lumbar spine was extracted and processed using western blot analysis to evaluate pain (c-fos expression). RESULTS: The results showed that c-fos expression was decreased significantly in all groups after each intervention (p < .05). In particular, TTG produced the most significant decrease compared to the other groups. CONCLUSION: These results suggest that treadmill exercise with initial pain control using TENS is a suitable method for relieving pain in knee osteoarthritis.
Keywords
Knee osteoarthritis; Pain management; TENS; Treadmill exercise;
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