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http://dx.doi.org/10.4082/kjfm.2010.31.5.384

A Case Report of Sepsis by Extended-Spectrum ${\beta}$-Lactamase Producing Escherichia Coli  

Lee, Seung-Beom (Department of Family Medicine, Yonsei University College of Medicine)
Kim, Choon-Ok (Department of Family Medicine, Yonsei University College of Medicine)
Kang, Hee-Cheol (Department of Family Medicine, Yonsei University College of Medicine)
Publication Information
Korean Journal of Family Medicine / v.31, no.5, 2010 , pp. 384-389 More about this Journal
Abstract
The overall prognosis of acute pyelonephritis is good, but the infections by extended spectrum ${\beta}$-lactamase (ESBL) producing Escherichia coli (E.coli) cause poor responses to empirical antibiotic treatment, and consequently increase mortality. ESBL can hydrolyze the antibiotics with a ${\beta}$-lactam ring and confer resistance to oxyimino-cephalosporins and monobactams. If the patient shows poor responses to empirical antibiotics or severe septic conditions, physicians must switch the antibiotics to other antibiotics covering resistant strains without delay. We report a case of acute pyelonephritis by extended-spectrum ${\beta}$-lactamase producing E.coli in a 29-year-old woman who was empirically treated with oral ciprofloxacin as an initial treatment, but progressed to sepsis.
Keywords
Acute Pyelonephritis; Extended Spectrum ${\beta}$-Lactamase; Escherichia Coli;
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