Identification of Atherosclerosis Related Gene Expression Profiles by Treatment of Benzo(a)pyrene in Human Umbilical Vein Endothelial Cells
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Lee, Sun-Hee
(Department of Microbiology (BK21) and Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, School of Medicine, Kyung Hee University)
Lee, Seung-Eun (Department of Microbiology (BK21) and Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, School of Medicine, Kyung Hee University) Ahn, Hyun-Jong (Department of Microbiology (BK21) and Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, School of Medicine, Kyung Hee University) Park, Cheung-Seog (Department of Microbiology (BK21) and Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, School of Medicine, Kyung Hee University) Cho, Jeong-Je (Department of Microbiology (BK21) and Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, School of Medicine, Kyung Hee University) Park, Yong-Seek (Department of Microbiology (BK21) and Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, School of Medicine, Kyung Hee University) |
1 | Plottner, S. et al. Evaluation of time dependence and interindividual differences in benzo[a]pyrene-mediated CYP1A1 induction and genotoxicity in porcine urinary bladder cell cultures. J Toxicol Environ Health A 71:969-975 (2008) DOI ScienceOn |
2 | Marcus, A. J. Thrombosis and inflammation as multicellular processes: pathophysiologic significance of transcellular metabolism. Blood 76:1903-1907 (1990) PUBMED ScienceOn |
3 | Oesterling, E., Toborek, M. & Hennig, B. Benzo[a] pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway. Toxicol Appl Pharmacol 232:309-316 (2008) DOI ScienceOn |
4 | Puranik, R. & Celermajer, D. S. Smoking and endothelial function. Prog Cardiovasc Dis 45:443-458 (2003) DOI ScienceOn |
5 | Chen, H. et al. Tobacco smoking inhibits expression of proinflammatory cytokines and activation of IL-1Rassociated kinase, p38, and NF-kappaB in alveolar macrophages stimulated with TLR2 and TLR4 agonists. J Immunol 179:6097-6106 (2007) DOI |
6 | Kurisaki, A. et al. The mechanism of nuclear export of Smad3 involves exportin 4 and Ran. Mol Cell Biol 26:1318-1332 (2006) DOI ScienceOn |
7 | Kim, Y. J, Lee, H. E. & Ryu, J. C. Identification of marker genes related to cardiovascular toxicity of doxorubicin & daunorubicin in Human Umbilical Vein Endothelial Cells (HUVEC). Mol Cell Toxicol 3:246-253 (2007) 과학기술학회마을 ScienceOn |
8 | Yan, Z. et al. Benzo[a]pyrene induces the transcription of cyclooxygenase-2 in vascular smooth muscle cells. J Biol Chem 275:4949-4955 (2000) DOI ScienceOn |
9 | Blockhuys, S. et al. Development of in vitro models for investigating spatially fractionated irradiation: physics and biological results. Phys Med Biol 54:1565-1578 (2009) DOI ScienceOn |
10 | Tonstad, S. & Andrew Johnston, J. Cardiovascular risks associated with smoking: a review for clinicians. Eur J Cardiovasc Prev Rehabil 13:507-514 (2006) DOI ScienceOn |
11 | Knaapen, A. M. et al. The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis. Mutat Res 621:31-41 (2007) DOI PUBMED ScienceOn |
12 | Libby, P. Inflammation in atherosclerosis. Nature 420:2724-2726 (2002) |
13 | Curfs, D. M. et al. Chronic exposure to the carcinogenic compound benzo[a]pyrene induces larger and phenotypically different atherosclerotic plaques in ApoEknockout mice. Am J Pathol 164:101-108 (2004) DOI ScienceOn |
14 | Kawakami, A. et al. Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation. Circ Res 103:1402-1409 (2008) DOI ScienceOn |
15 | Annas, A., Brittebo, E. & Hellman, B. Evaluation of benzo(a)pyrene-induced DNA damage in human endothelial cells using alkaline single cell gel electrophoresis. Mutat Res 471:145-155 (2000) DOI PUBMED ScienceOn |
16 | Park, Y. S. et al. Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase. Arterioscler Thromb Vasc Bio 27:1319-1325 (2007) DOI ScienceOn |
17 | Curfs, D. M. et al. Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties. FASEB 19:1290-1292 (2005) DOI ScienceOn |
18 | Hoffmann, D., Melikian, A. A. & Brunnemann, K. D. Studies in tobacco carcinogenesis. IARC Sci Publ 105:482-484 (1991) PUBMED |
19 | Wang, L., Wang, H., & Zhang, X. Effects of tobacco smoke on the expression of ICAM-1 in human umbilical vein endothelial cells. Zhonghua Yu Fang Yi Xue Za Zhi 35:105-107 (2001) PUBMED |
20 | Koul, A., Singh, M. & Gangar, S. C. Modulatory effects of different doses of alpha-tocopherol on benzo (a)pyrene-DNA adduct formation in the pulmonary tissue of cigarette smoke inhaling mice. Indian J Exp Biol 43:1139-1143 (2005) PUBMED ScienceOn |
21 | Berwanger, C. S., Jeremy, J. Y. & Stansby, G. Homocysteine and vascular disease. British Journal of Surgery 82:726-731(2005) DOI ScienceOn |
22 | Ramos, K. S., Bowes, R. C., Ou, X. & Weber, T. J. Responses of vascular smooth muscle cells to toxic insult: cellular and molecular perspectives for environmental toxicants. J Toxicol Environ Health 43:419-440 (1994) DOI PUBMED ScienceOn |
23 | Tithof, P. K. et al. Polycyclic aromatic hydrocarbons present in cigarette smoke cause endothelial cell apoptosis by a phospholipase A2-dependent mechanism. Faseb J 16:1463-1464 (2002) DOI ScienceOn |
24 | Busse, R. & Fleming, I. Endothelial dysfunction in atherosclerosis. J Vasc Res 33:181-194 (1996) DOI ScienceOn |
25 | Van Grevenynghe, J. et al. Human endothelial progenitors constitute targets for environmental atherogenic polycyclic aromatic hydrocarbons. Biochem Biophys Res Commun 341:763-769 (2006) DOI ScienceOn |
26 | Gerde, P. et al. Benzo[a]pyrene at an environmentally relevant dose is slowly absorbed by, and extensively metabolized in, tracheal epithelium. Carcinogenesis 18:1825-1832 (1997) DOI ScienceOn |
27 |
Stvrtinov |
28 | Huber, G. L. et al. Marijuana and tobacco smoke gasphase cytotoxins. Pharmacol Biochem Behav 40:629-636 (1991) DOI ScienceOn |
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