Evaluation of the Genotoxicity of Decursin and Decursinol Angelate Produced by Angelica gigas Nakai |
Kim, Kang-Min
(Department of Smart Foods and Drugs, Inje University)
Kim, Tae-Ho (Department of Smart Foods and Drugs, Inje University) Park, Yun-Jung (Department of Smart Foods and Drugs, Inje University) Kim, Ik-Hwan (College of Life Sciences and Biotechnology, Korea University) Kang, Jae-Seon (Department of Pharmacy, Kyungsung University) |
1 | Ryu, K. S., Hong, N. D. Kim, N. J. & Kong, Y. Y. Studies on the coumarin constituents of the root of Angelica gigas Nakai. Isolation of decursinol angelate and assay of decursinol angelate and decursin. Kor J Pharmacogn 21:64-68 (1990) |
2 | Lee, S. H. et al. Antibacterial courmins from Angelica gigas roots. Arch Pharm Res 26:449-452 (2003) DOI ScienceOn |
3 | Ahn, K. S., Sim, W. S. & Kim, I. H. Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas. Planta Med 62:7-9 (1996) DOI ScienceOn |
4 | Maron, D. M. & Ames, B. N. Revised methods for the salmonella mutagenicity test. Mutat Res 113:173-215 (1983) DOI PUBMED |
5 | Yu, Y. B. & Jo, S. K. Evaluation on the safety of -irradiated Angelica gigas Nakai: Stability of acitve components and safety in genotoxicity test. J Korean Soc Food Sci Nutr 29:300-306 (2000) |
6 | Jenderny, J., Walk, R. A., Hackenberg, U. & Rohrborn, G. Chromosomal abnormalities and sister-chromatid exchange in bone marrow cells of mice and Chinese hamster after inhalation and intraperitoneal administration. Mutat Res 203:1-10 (1988) DOI PUBMED ScienceOn |
7 | Yim, D. S. et al. A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. Cancer Res 65:1035-1044 (2005) PUBMED |
8 | Ames, B. N., Durston, W. E., Yamasaki, E. & Lee, F. D. Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection. Proc Natl Acad Sci 70:2281-2285 (1973) DOI ScienceOn |
9 | Ryu, J. C. & Kim, Y. J. Evaluation of the genetic toxicity of synthetic chemicals (IX)- a synthetic selective herbicide, pretilachor-. J Environ Toxicol 19:93-100 (2004) 과학기술학회마을 |
10 | Yook, C. S. Coloured medicinal plants of Korea, Academy Book Co., Seoul (1990) |
11 | Ishidate, M. Jr. & Odashima, S. Chromosome tests with 134 compounds on Chinese hamster cells in vitro. Mutat Res 48:337-354 (1977) DOI PUBMED ScienceOn |
12 | Galloway, S. M. et al. Multilaboratory comparison of in vitro tests for chromosome aberrations in CHO and CHL cells tested under the same protocols. Environ Mol Mutangenesis 29:189-207 (1997) DOI ScienceOn |
13 | Zimmermann, F. K. Induction of mitotic gene conversion by mutagens. Mutat Res 11:327-337 (1971) PUBMED |
14 | Mersch-Sundermann, V. S., Kerekordes, S. & Mochayedi, S. Sources of variability of the Escherichia coli PQ 37 genotoxicity assay (SOS chromotest). Mutation Res 252:51-60 (1991) DOI PUBMED ScienceOn |
15 | Kang, S. Y. et al. Coumarins isolated from Angelica gigas inhibit acetylcholinesterase structure-activity relationships. J Nat Prod 64:683-685 (2001) DOI ScienceOn |
16 | Ryu, J. C., Kim, H. J., Seo, Y. R. & Kim, K. R. Single cell gel electrophoresis (comet assay) to detect DNA damage and apoptosis in cell level. Environ Mut Carcinogens 17:71-77 (1997) 과학기술학회마을 |
17 | Hayashi, M., Sofuni, T. & Ishidate, M. Jr. High-sensitivity in micronucleus induction of mouse strain. Mutat Res 105:253-256 (1982) DOI ScienceOn |
18 | Ryu, J. C. et al. A study on the antimutagenic effect f cinnamic acid derivatives in Escherichia coli PQ 37 (SOS Chromotest) (I). Environ Mut Carcinogens 13:8-17 (1993b) |
19 | Lee, S. H. et al. Anti-tumor activities of decursinol angelate and decursin from Angelica gigas. Arch Pharm Res 26:727-730 (2003) DOI ScienceOn |
20 | Dunnett, C. W. A multiple comparison procedure for comparing several treatments with the control. J Am Stat Assoc 50:1096-1121 (1955) DOI ScienceOn |
21 | Hayashi, M. et al. The micronucleus assay with mouse peripheral blood reticulocytes using acridine orangecoated slides. Mutat Res 245:245-249 (1990) DOI ScienceOn |
22 | Matsuoka, A., Hayashi, M. & Ishidate, M. Chromosomal aberration test on 29 chemicals combined with S-9 mix in vitro. Mutat Res 66:277-290 (1979) DOI ScienceOn |
23 | Radman, M., Jeggo, P. & Wagner, R. Chromosomal rearrangement and carcinogenesis. Mutat Res 98:249-264 (1982) DOI PUBMED ScienceOn |
24 | Sato, T. et al. Evaluation of the SOS chromotest for the detection of antimutagens. Environ Mol Mutagenesis 17:258-263 (1991) DOI ScienceOn |
25 | Ahn, M. J., Lee, M. K., Kim, Y. C. & Sung, S. H. The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry. J Pharmaceut Biomed 46:258-266 (2008) DOI ScienceOn |
26 | Lee, W. S. et al. Genetic toxicity test of 8-hydroxyquinoline by Ames Micronucleus comet assays and microarray analysis. Mol Cell Toxicol 3:90-97 (2007) |
27 | McCann, J. & Ames, B. N. Detection of carcinogens as mutagens in the Salmonella/microsome test: Assay of 300 chemicals: . Proc Nat Acad Sci 73:950-954 (1976) DOI ScienceOn |
28 | Konoshima, M., Chi, H. J. & Hata, K. Coumarins from The root of Angelica gigas Nakai. Chem Pharm Bull 16:1139-1140 (1968) DOI PUBMED ScienceOn |