Lack of Association between Serotonin Transporter Promoter Gene Polymorphism and Citalopram Response in Major Depressive Disorder
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Kang, Rhee-Hun
(Department of psychiatry, College of Medicine, Korea University)
Choi, Myoung-Jin (Clinical Research Center for Depression, Korea University) Chang, Hun-Soo (Clinical Research Center for Depression, Korea University) Hahn, Sang-Woo (Department of psychiatry, College of Medicine, Soonchunhyang University) Lee, Hwa-Young (Department of psychiatry, College of Medicine, Korea University) Paik, Jong-Woo (Department of Psychiatry, College of medicine, Kyunghee university) Lim, Se-Won (Department of psychiatry, College of medicine, Sungkyunkwan University Kangbuk Samsung Hospital, School of Medicine) Oh, Kang-Seob (Department of psychiatry, College of medicine, Sungkyunkwan University Kangbuk Samsung Hospital, School of Medicine) Jung, Han-Yong (Department of psychiatry, College of Medicine, Soonchunhyang University) Lee, Min-Soo (Department of psychiatry, College of Medicine, Korea University) |
1 | Smeraldi, E. et al. Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry 3:508-511 (1998) DOI |
2 | Smits, K. M. et al. Influence of SERTPR and STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review. Mol Psychiatry 9:433-441 (2004) DOI ScienceOn |
3 | Martin, R. M., Hilton, S. R., Kerry, S. M. & Richards, N. M. General practitioners' perceptions of the tolerability of antidepressant drugs: a comparison of selective serotonin reuptake inhibitors and tricyclic antidepressants. BMJ 314:646-651 (1997) DOI ScienceOn |
4 | Ramamoorthy, S. et al. Antidepressant-and cocainesensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proc Natl Acad Sci USA 90:2542-2546 (1993) |
5 | Kim, D. K. et al. Serotonin transporter gene polymorphism and antidepressant response. Neuroreport 11: 215-219 (2000) DOI ScienceOn |
6 | Greenberg, B. D. et al. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. Am J Med Genet 88:83-87 (1999) DOI ScienceOn |
7 | Arias, B., Catalan, R., Gasto, C., Gutierrez, B. & Fananas, L. 5-HTTLPR polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-weeks follow up study. J Clin Psychopharmacol 23:563-567 (2003) DOI ScienceOn |
8 | Williams, R. B. Neurobiology, cellular and molecular biology, and psychosomatic medicine. Psychosom Med 56:308-315 (1994) DOI |
9 | Zanardi, R., Benedetti, F., Di Bella, D., Catalano, M. & Smeraldi, E. Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene. J Clin Psychopharmacol 20:105-107 (2000) DOI ScienceOn |
10 | Yoshida, K. et al. Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 26:383-386 (2002) DOI ScienceOn |
11 | Lesch, K. P. et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 29:1527-1531 (1996) |
12 | Kim, J. W. Association study and the population admixture. Winter Workshop on Human Neurobehavioral Genetics in the 21st Century. Seoul. Korean Society of Biological Psychiatry (2003) |
13 | Rothman, K. J. No adjustments are needed for mutiple comparisons. Epidemiology 1:43-46 (1990) DOI ScienceOn |
14 | Owens, M. J. & Nemeroff, C. B. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clin Chem 40:288-295 (1994) |
15 | Kim, H. et al. Monoamine transporter gene polymorphisms and antidepressant response in Koreans with late-life depression. JAMA 296:1609-1618 (2006) DOI ScienceOn |
16 | Baumann, P. & Rochat, B. Comparative pharmacokinetics of selective serotonin reuptake inhibitors: a look behind the mirror. Int Clin Psychopharmacol 10: 15-21 (1995) DOI |
17 | Buchner, A., Faul, F. & Erdfelder, E. G.Power: A priori, post-hoc, and compromise power analyses for the Macintosh (Version 2.1.1) [Computer Program]. Trier, University of Trier (1996) |
18 | Heils, A. et al. Allelic variation of human serotonin transporter gene expression. J Neurochem 66:2621-2624 (1996) DOI ScienceOn |
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