Gene Expression Analysis of Anticancer Drug Induced Hepatotoxicity Using cDNA Microarray |
Lee, Gyoung-Jae
(Research Institute. Shin-Won Scientific Co., Ltd.)
Kim, Yang-Suk (Bioinformatics Unit, ISTECH Inc.) Jung, Jin-Wook (Department of Biochemistry and Molecular Biology, Hanyang University & Genocheck Co., Ltd) Hwang, Seung-Yong (Department of Biochemistry and Molecular Biology, Hanyang University & Genocheck Co., Ltd) Park, Joon-Suk (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) Kang, Kyung-Sun (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) Lee, Yong-Soon (Department of Veterinary Public Health, College of Veterinary Medicine, Seoul National University) Chon, Man-Suk (Research Institute. Shin-Won Scientific Co., Ltd.) Chon, Kum-Jin (Research Institute. Shin-Won Scientific Co., Ltd.) Kang, Jong-Soo (Research Institute. Shin-Won Scientific Co., Ltd.) Kim, Dong-Hyean (KIST) Park, Young-Keun (Department of Biotechnology and Genetic Engineering Korea University) |
1 | Marilyn, J.A. & MacGregor, J.T. Toxicology and genetic toxicology in the new era of 'Toxicogenomics': impact of '-omics' technologies. Mut Research 499, 13-25 (2002) DOI ScienceOn |
2 | Steven, J.B. et al. RNA expression in the early characterization of hepatotoxicants in Wistar rats by high -density DNA microarrays. Hepatology 33, 1239- 1258 (2001) DOI ScienceOn |
3 | Lee, G.J. et al. cDNA microarray gene expression analysis and toxicological phenotype for anticancer drug. J Vet Med Sci. 66(11), 1339-1345 (2004) DOI ScienceOn |
4 | Kramer, J.A. et al. Acute molecular markers of Rodent hepatic carcinogenesis identified by transcription profiling. Chem Res Toxicol. 17, 463-470 (2004) DOI ScienceOn |
5 | Karahara, T. et al. The gene expression of hepatic proteins responsible for DNA repair and cell proliferation in tamoxifen-induced hepatocarcinogenesis. Cancer Sci. 94, 582-588 (2003) DOI ScienceOn |
6 | Waring, J.F. et al. Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. Toxicol Appl Pharmacol. 175(1), 28-42 (2001) DOI ScienceOn |
7 | Qihong, H. et al. Gene expression profiling reveals multiple toxicity end point induced by hepatotoxicants. Mutation Research 549, 147-168 (2004) DOI |
8 | Dettling, M. & Buhlmann, P. Boosting for tumor classification with gene expression data. Bioinformatics 19, 1061-1069 (2003) DOI ScienceOn |
9 | Dudoit, S. & Fridlyand, J. A prediction-based resampling method for estimating the number of clusters in a dataset. Genome Biol. 3, 25 (2003) |
10 | Yang, Y.H. et al. Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res. 30, e15 (2002) DOI |
11 | Hawkin, R.A. et al. Tamoxifen increases apoptosis but does not influence markers of proliferation in an MCF-7 xenograft model of breast cancer. Breast 9, 96-106 (2000) DOI ScienceOn |
12 | Park, P.J., Pagano, M. & Bonetti, M. A nonparametric scoring algorithm for identifying informative genes from microarray data. Pac Symp Biocomput. 6, 52-63 (2001) |
13 | D'Mello, D., Mehta, D., Pereira, J. & Rao, C.V. A toxicity study of simultaneous administration of Tamoxifen and Diazepam to female Wistar rats. Exp Toxicol Pathol. 51(6), 549-553 (1999) DOI |
14 | Feng, K.K. et al. Combined therapy with flk1-based DNA vaccine and interleukin-12 results in enhanced antiangiogenic and antitumor effects. Cancer Lett. 18, 221(1), 41-47 (2005) DOI ScienceOn |
15 | Gary, E.M. Toxicogenomics and toxic torts. Trends in Biotech. 20, 329-332 (2002) DOI ScienceOn |
16 | Hamadeh, H.K. et al. Gene Expression analysis reveals chemical-specific profiles. Toxicological Sciences 27, 219-231 (2002) DOI ScienceOn |
17 | Ganter, B. et al. Develpoment of large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action. J of Biotechnology 119, 219-244 (2005) DOI ScienceOn |
18 | Rapa, I. et al. Cathepsin K Is Selectively Expressed in the Stroma of Lung Adenocarcinoma but not in Bronchioloalveolar Carcinoma. Am J Clin Pathol. 125(6), 847-854 (2006) DOI |