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Clinical study of guided bone regeneration of extracted socket with PLA/PGA membrane and silk fibroin membrane  

Hwang, Woo-Jin (Department of Periodontology, School of Dentistry, Wonkwang University)
Jeong, Seong-Nyum (Department of Periodontology, School of Dentistry, Wonkwang University)
Kim, Yun-Sang (Department of Periodontology, School of Dentistry, Wonkwang University)
Pi, Sung-Hee (Department of Periodontology, School of Dentistry, Wonkwang University)
You, Hyung-Keun (Department of Periodontology, School of Dentistry, Wonkwang University)
Chung, Chong-Pyoung (Department of Periodontology, School of Dentistry, Seoul National University, NIBEC Inc.)
Shin, Hyung-Shik (Department of Periodontology, School of Dentistry, Wonkwang University)
Publication Information
Journal of Periodontal and Implant Science / v.39, no.2, 2009 , pp. 129-138 More about this Journal
Abstract
Purpose: This study was designed to compare the bond regeneratiom effects of treatment using silk fibroin membrane ( Nanogide-S$^{(R)}$ ) resorbable barrier with control group treated by polyactic acid / polylacticglycolic acid membrane(Biomesh$^{(R)}$ ) Methods: 44 severe bone loss on extraction socket from 44 patients were used in this study. In experimental group 22 sites of them were treated by silk fibrin membrane as and the other 22 sites were treated by polyactic acid/ polylacticglycolic acid membrane as a control group. Clinical parameters including recovered bone width, length and radiographic parameter of vertical length were evlauated at base line and 3 months after surgery. Results: 1) Severe bone width, length was significantlly decreased in two group. 2) Bone width, length was significantlly decreased in two group. 3) Decreased bone width, length and radiographic examination differences between group. Conclusions: On the basis of these results, silk fibrin resorbable membrane has similar bone regeneration ability to polyactic acid / polylacticglycolic acid membrane in guided bone regeneration for severe bone loss defect on extraction socket.
Keywords
fibroin; polylactic acid-polyglycolic acid copolymer; regeneration;
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