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An Assessment on effect of Bioabsorbable membrane, allogenic bone and Platelet Rich Plasma in Class II furcation involvement by digital subtraction radiography  

Kim, Sang-Hoon (Department of Periodontology, College of Dentistry, Dan-kook University)
Lim, Sung-Bin (Department of Periodontology, College of Dentistry, Dan-kook University)
Chung, Chin-Hyung (Department of Periodontology, College of Dentistry, Dan-kook University)
Publication Information
Journal of Periodontal and Implant Science / v.32, no.1, 2002 , pp. 173-186 More about this Journal
Abstract
The purpose of this study was to evaluate effect of platelet rich plasma on the treatment of Grade II furcation involvement, with Demineralized Freeze-Dried Bone(Dembone(R)) and bioabsorable membrane(BioMesh(R)) in humans by digital subtraction radiography. 12 teeth(control group) were treated with Demineralized Freeze-Dried Bone(Dembone(R)) and bioabsorable membrane(BioMesh(R)), and 12 teeth(test group) were treated with Demineralized Freeze-Dried Bone(Dembone(R)), bioabsorable membrane(BioMesh(R)) and Platelet Rich Plasma. The change of bone density was assessed by digital subtraction radiography in this study. The change of mineral content by as much as 5%(vol) could be perceived in the subtracted images. The change of mineral content was assessed in the method that two radiographs are put into computer program to be overlapped and the previous image is subtracted by the later one. Both groups were statistically analyzed by Wilcoxon signed Ranks Test and Mann-whitney Test using SPSS program (5% significance level). The results were as follows: 1. In test group, the radiopacity in 3 months after surgery were significantly increased than 1 month after surgery(p<0.05). However. there were no significant difference between 1 month after surgery and 3 months after surgery in control group(p>0.05). 2. In test and control group, the radiopacity in 6 months after surgery were significantly increased than 1 month after surgery(p<0.05) 3. In test and control group, the radiopacity in 6 months after surgery were significantly increased than 3 months after surgery(p<0.05). 4. There were no significant difference between test group and control group at 1 month, 3 months after surgery, but radiopacity in test group were significantly increased than control group at 6 months after surgery(p<0.05). In conclusion, Platelet Rich Plasma can enhance bone density.
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1 Hurzeler MB, Kohal RJ, Naghshbandi J, Mota LF, Conradt J, Hutmacher D, Caffesse RG: Evaluation of a New Bioresorbable Barrier to Facilitate Guided Bone Regeneration Around Exposed Implant Threads. Int J Oral Maxillofac Surg 1998; 27: 315-320   DOI   ScienceOn
2 Glickman, I. : Clinical Periodontology,ed 7. Philadelphia, W. B. Sauders Co,1990
3 Becker, W., Becker, B. E., Berg, L., Prichard, J., Caffesse, R. G. & Rosenberg, E. : New attachment after treatment with root isolation procedures in class III and class II furcations and vertical osseous defects. International Journal of Periodontology and Restorative Dentisty 1988;3:9-23
4 Terranova VP, Franzetti LC, Hick S, Wikesjo VME. : Biochemically mediated periodontal regeneration. J Periodont Res 1987;22:248-251   DOI   PUBMED
5 Centrella M, McCarthy TL and Canalis E. : TGF-$\beta$ is a bifunctional regulator of recplication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone. J Bio Chem 1987; 262: 2874-2896
6 Subburaman Mohan : Bone growth Factors. Clinical Orthopaedics and related research 1991; 263: 30-48
7 Wikesjo UME, Sigurdsson TJ: Guided Bone Regeneration: Is it a reproducible technique? J Parodontol Implantol Orale 1994; 13: 243-257
8 Pitaru S, Tal H, Soldinger M, Azar-Avidan O, Noff M: Collagen Membrane Prevent the Apical Migration of Epithelium During Periodontal Wound Healing. J Periodont Res 1987; 22: 331-333   DOI
9 Black BC, Gher ME, Sandifer JB, Fucini SE, Rechardson AC: Comparative Study of Collagen and e-PTFE Membranes in the Treatment of Human Class II Furcation Defects. J Periodontol 1994; 65: 598-604   DOI
10 Caffesse RG, Nasjleti CE, Morrison EC, Sanchez R: Guided Tissue Regeneration: Comparison of Bioabsorbable and Nonbioabsorbable Membranes. Histologic and Histometric Study in Dogs. J Periodontol 1994; 65: 583-591   DOI
11 Brooks. D.B. Heiple.K.G. et al : Immunological factors in homogeneous bone transplantation. Ⅳ. The effect of various methods of preparation and irradiation on antigenicity. J. bone Joint Surg 1963; 45: 1617   DOI
12 Urist, M. R., Silverman B. F. : The bone induction principle. Clin Orthop 1967; 53: 243
13 Caffesse RG, Nasjleti CE, Plotzke AE, Anderson GB, Morrison EC: Guided Tissue Regeneration and Bone Grafts in the Treatment of Furcation Defects. J Periodontol 1993; 64: 1145-1153   DOI
14 Wallace SC, Gellin RG, Miller MC, Mishkin DJ: Guided Tissue Regeneration With and Without Decalcified Freeze-Dried Bone in Mandibular Class II Furcation Invasions. J Periodontol 1994; 65: 244-254   DOI
15 Grondahl H, Grondahl K. : Subtraction radiography for the diagnosis of periodontal bone lesions. Oral Surg 1983; 55: 208.   DOI   ScienceOn
16 Grondahl H, Grondahl K, Webber RL : A digital subtraction technique for dental radiography. Oral Surg Oral Med Oral Pathol 1988; 65: 490-494   DOI   ScienceOn
17 Ruttimann UE, Webber RL : Volumetry of localized bone lesions by subtraction radiography. J Periodontal Res. 1987; 22: 215-216   DOI
18 Bragger U, Hammerle CHF : Remodelling of periodontal tissues adjacent to sites treated according to the principles of guided tissue regeneration. J Clin Periodontol. 1992; 19: 615-624   DOI   ScienceOn
19 Matsuda N, Lin WL, Kumar NM, Cho MI and Genco RJ.: Mitogenic chemotactic and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontol 1992; 63: 515-525   DOI   PUBMED
20 Antosz ME, Bellows CG and Aubin JE.: Effects of TGF- $\beta$and epidermal growth factor on celll proliferation and the formation of bone nodules in isolated fetal rat calvaria cells. J Cell Physiol 1989; 140: 386-393   DOI   PUBMED
21 Terranova VP, Hick S, Franzetti L, Lyall RM, Wikesso VME. : A biochemical approach to periodontaol regeneration, AFS CM, Assay for specific cell migration. J Periodontol 1987;58:247-259
22 Fleisher N, Waal HD, Bloom A: Regeneration of Lost Attachment Apparatus in the Dog Using Vicryl Absorbable Mesh(Polyglactic 910). Int J Periodont Rest Dent 1988; 8: 45-55
23 Edward S. Cohen : Atlas of Cosmetic and Reconstructive Periodontal Surgery, 2nd edition
24 Galgut, P. N. : Oxidized cellulose mesh used as a biodegradable barrier membrane in the technique of guided tissue regeneration. A Case report. J Periodontol 1990; 61: 766-768   DOI   PUBMED
25 Lynch SE. Williams RC, Polson AM, Howell TH, Reddy Ms, Zappa UE, Antoniades HN. : A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clin Periodontol 1989; 16: 545-548   DOI
26 Turner. D.W. and Melloonig.J.T : Antigenicity of freeze-dried bone allograft in periodontal osseous defects. J periodontal Res 1981; 16(1):89-99   DOI
27 Tayapongsak P, O'Brien DA, Monteiro CB and Arceo-Diaz LL.: Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. J Oral Maxillofac Surg 1994; 52: 161-166   DOI   ScienceOn
28 Keski-Oja J, Leof EB, Lyons RM, Coffey RJ and Jr. Moses HL.: Transforming growth factor and control of neoplastic cell growth. J Cell Biochem 1987; 33: 95-107   DOI   PUBMED
29 Meffert, R. M., Thomas, J. R. : Hydroxylapatite as an alloplastic graft in the treatment of human periodontal osseous defects. J Periodontol 1985; 56: 63-73
30 Pontoriero, R., Lindhe, J., Nyman, S., Karring, T., Rosenberg, E. & Sanavi, F. : Guided tissue regeneration in degree II furcation-involved mandibular molars. A clinical study. J Periodontol 1988;15:247-254   DOI
31 Pontoriero, R., Nyman, S. : Guided tissue regeneration in degree Ⅱ furcation -involved mandibular molars. A clinical study. J Clin Periodontol 1988; 15: 247-254   DOI
32 Rutherford RB, Trilsmith MD, Ryan HE and Charette MF.: Synergistic effects of dexamethasone on platelet-derived growth factors mitogenesis in vitro. Arch Oral Biol 1992; 37: 139-145   DOI   ScienceOn
33 Howell TH, Fiorellini JP and Paquette DW.: A phase I/II clinical trial to evaluation a combination of recombinant human plateletderived growth factor-BB and recombinant human insulin-like growth factor-I in patients with periodontal disease. J Periodontol 1997; 68: 1186-1193   DOI
34 Bowers GM, Chadorff B, Carnevale R, Mellonig JT, Corio R, Emerson J, Stevens J, Romberg E: Histologic Evaluation of New Attachment Apparatus Formation in Humans. Part II. J Periodontol 1989; 60: 675-682   DOI
35 Hildebolt CF, Vanier MW : Quantitative evaluation of digital dental radiograph imaging systems. Oral Surg Oral Med Oral Pathol. 1990; 70: 661-668   DOI   ScienceOn
36 Wikesjo, U., Nilveus, R. E. : significance of early healing events on periodontal repair. A review. J Periodontol 1992; 63: 158-165   DOI
37 Stahl, S. Frou, S. : Histologic and clinical responses to porous hydroxylapatite implants in human periodontal defects. J Periodontol 1987; 58: 689-695   DOI
38 Robert E. Marx, Eric R. : Platelet rich plasma growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Indod 1998; 85: 638-646   DOI
39 Rutherford, R. B., Hiekrash, C. E. : Plateletderived growth factor and insulin-like growth factors stimulate regeneration of periodontal attachment in monkeys. J Periodont. Res. 1992; 27: 285-290   DOI
40 Proestkis G., Bratthall G : Guided tissue regeneration in the treatment of infrabony defects on maxillary premolars. A pilot study. J Clin Periodontol. 1992; 19: 766-773   DOI
41 Lu H. : Topographical characteristes of root trunk length related to guided tissue regeneration. J Periodontol 1992; 63: 215-219   DOI   PUBMED
42 Oates TW, Rouse CA and Cochra DI.: Mitogenic effects of growth factors on human periodontal ligament cells in vitro. J Periodontol 1993; 64: 142-148   DOI   PUBMED
43 Jeffcoat M. : Radiographic methods for dection of progressive alveolar bone loss. J Periodontol 1992; 63: 367-372   DOI   PUBMED
44 Caffesse, R. G., Smith, B. A. : New attachment achieved by guided tissue regeneration in the beagle dogs. J Periodontol 1988; 59: 589-594   DOI
45 Gottlow J, Nyman S, Lindhe J, Karring T: New Attachment Formation in the Human Periodontium by Guided Tissue Regeneration. J Clin Periodontol 1986; 13: 604-616   DOI
46 Bowers GM, Chadorff B, Carnevale R, Mellonig JT, Corio R, Emerson J, Stevens J, Romberg E: Histologic Evaluation of New Attachment Apparatus Formation in Humans. Part I. J Periodontol 1989; 60: 664-674   DOI
47 Christgau M., Schmalz G. : Clinical and radiographical split-mouth study on resorbable versus non-resorbable GTR membrane. J Clin Periodontol. 1995; 22: 306-315   DOI   ScienceOn
48 Isidor, F., Karring, T. : New attachment formation on citric acid treated roots. J Periodont. Res. 1985; 20: 421-430   DOI
49 Pontoriero, R., Nyman, S., Lindhe, J. : Guided tissue regeneration in surgically produced furcation defects. An experimental study in the beagle dogs. J Periodontol 1992; 19: 159-163   DOI
50 Lundgren D, Slotte C: Reconstruction of Anatomically Complicated Periodontal Defects Using a Bioresorbable GTR Barrier Supported by Bone Mineral. A 6-Month Follow-Up Study of 6 Cases. J Clin Periodontol 1999; 26: 56-62   DOI   ScienceOn
51 Moon-Il Cho, Wen-Lang Lin : Platelet-Derived Growth Factor-Modulated Guided Tissue Regenerative Therapy. J Periodontol 1995; 66: 522-530   DOI
52 Sporn MB, Roberts AB, Wakefield LM and de Crombrugghe B.: Some recent advances in the chemistry and biology of TGF-$\beta$. J Cell Biol 1987; 105: 1039-1045   DOI   ScienceOn
53 Giannobile WV, Finkelman RD and Lynch SE.: Comparison of canine and non-human primate animal models for periodontal regenerative therapy: Results following a single administration of PDGF/IGF-I. J Periodontol 1994; 65: 1158-1168   DOI   PUBMED
54 Simon M, Dahlin C : Qualitative and quantitative comparative study on different filling materials used in bone tissue regeneration : A controlled clinical study. Int J periodontics restorative Dent 1994; 14: 198-215
55 Anderegg CR, Marin SJ, Gray JL, Mellonig JT, Gher ME: Clinical Evaluation of the Use of Decalcified Freeze-Dried Bone Allograft With Guided Tissue Regeneration in the Treatment of Molar Furcation Invasions. J Periodontol 1991; 62: 264-268   DOI
56 Machtei E, Dunford R. : Gingival recession and exposure of barrier membrane: effect on guided tissue regeneration of class II furcation defects. Int J Periodontics Restorative Dent 1995; 15: 590-599
57 Urist, M. R. : Bone formation by autoinduction. Science 1965; 150: 893   DOI   ScienceOn
58 Libin, B. M., Ward, H. L. : Decalcified lyophilized bone allografts for use in human periodontal defects. J periodontol 1975; 46: 51   DOI
59 Caffesse, R. G., Smith, B. A., Duff, B., Morrison, E. C., Merrill, D. & Becker. W.: Class II furcations treated by guided tissue regeneration in humans : Case reports. J Periodontol 1990; 61: 510-514   DOI   PUBMED
60 Gottlow J, Nyman S : New attachment formation as the result of controlled tissue regeneration. J Clin Periodontol 1984; 11: 494-503   DOI
61 Lynch SE. : Platelet-derived growth factor and insulin-like growth factor. I. Mediators of healing in soft tissue and bone wounds. Periodont Case Rep 1991; 13: 13-20
62 Anderegg CR, Marin SJ, Gray JL, Mellonig JT, Gher ME: Clinical Evaluation of the Use of Decalcified Freeze-Dried Bone Allograft With Guided Tissue Regeneration in the Treatment of Molar Furcation Invasions. J Periodontol 1991; 62: 264-268   DOI
63 Nilveus, R. egelberg, J. : The effect of topical citrical acid application of the healing of experimental furcation defects in dogs. The relative importance of coagulum support, flap design and systemic antibiotics. J Periodont. Res. 1980; 15: 551-560   DOI
64 Grondahl H, Grondahl K, Webber RL : A digital subtraction technique for dental radiography. Oral Surg 1983; 55: 96   DOI   ScienceOn