Prevalence and abundance of 9 periodontal pathogens in the saliva of periodontally healthy adults and patients undergoing supportive periodontal therapy |
Jung, Woo-Ri
(Department of Periodontology, Dental and Life Science Institute, Pusan National University School of Dentistry)
Joo, Ji-Young (Department of Periodontology, Dental and Life Science Institute, Pusan National University School of Dentistry) Lee, Ju-Youn (Department of Periodontology, Dental and Life Science Institute, Pusan National University School of Dentistry) Kim, Hyun-Joo (Department of Periodontology, Dental and Life Science Institute, Pusan National University School of Dentistry) |
1 | Haffajee AD, Japlit M, Bogren A, Kent RL Jr, Goodson JM, Socransky SS. Differences in the subgingival microbiota of Swedish and USA subjects who were periodontally healthy or exhibited minimal periodontal disease. J Clin Periodontol 2005;32:33-9. DOI |
2 | Kanasi E, Ayilavarapu S, Jones J. The aging population: demographics and the biology of aging. Periodontol 2000 2016;72:13-8. DOI |
3 | Feres M, Teles F, Teles R, Figueiredo LC, Faveri M. The subgingival periodontal microbiota of the aging mouth. Periodontol 2000 2016;72:30-53. DOI |
4 | Percival RS, Challacombe SJ, Marsh PD. Age-related microbiological changes in the salivary and plaque microflora of healthy adults. J Med Microbiol 1991;35:5-11. DOI |
5 | Preza D, Olsen I, Willumsen T, Boches SK, Cotton SL, Grinde B, et al. Microarray analysis of the microflora of root caries in elderly. Eur J Clin Microbiol Infect Dis 2009;28:509-17. DOI |
6 | Finoti LS, Corbi SC, Anovazzi G, Teixeira SR, Capela MV, Tanaka MH, et al. Pathogen levels and clinical response to periodontal treatment in patients with Interleukin 8 haplotypes. Pathog Dis 2013;69:21-8. |
7 | Doungudomdacha S, Rawlinson A, Walsh TF, Douglas CW. Effect of non-surgical periodontal treatment on clinical parameters and the numbers of Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans at adult periodontitis sites. J Clin Periodontol 2001;28:437-45. DOI |
8 | Choi H, Kim E, Kang J, Kim HJ, Lee JY, Choi J, et al. Real-time PCR quantification of 9 periodontal pathogens in saliva samples from periodontally healthy Korean young adults. J Periodontal Implant Sci 2018;48:261-71. DOI |
9 | Hyvarinen K, Laitinen S, Paju S, Hakala A, Suominen-Taipale L, Skurnik M, et al. Detection and quantification of five major periodontal pathogens by single copy gene-based real-time PCR. Innate Immun 2009;15:195-204. DOI |
10 | Listgarten MA, Sullivan P, George C, Nitkin L, Rosenberg ES, Chilton NW, et al. Comparative longitudinal study of 2 methods of scheduling maintenance visits: 4-year data. J Clin Periodontol 1989;16:105-15. DOI |
11 | Shiau HJ, Reynolds MA. Sex differences in destructive periodontal disease: exploring the biologic basis. J Periodontol 2010;81:1505-17. DOI |
12 | Han YW. Fusobacterium nucleatum: a commensal-turned pathogen. Curr Opin Microbiol 2015;23:141-7. DOI |
13 | Zhuang LF, Watt RM, Mattheos N, Si MS, Lai HC, Lang NP. Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues. Clin Oral Implants Res 2016;27:13-21. |
14 | Signat B, Roques C, Poulet P, Duffaut D. Fusobacterium nucleatum in periodontal health and disease. Curr Issues Mol Biol 2011;13:25-36. |
15 | Haffajee AD, Cugini MA, Tanner A, Pollack RP, Smith C, Kent RL Jr, et al. Subgingival microbiota in healthy, well-maintained elder and periodontitis subjects. J Clin Periodontol 1998;25:346-53. DOI |
16 | Lundmark A, Hu YO, Huss M, Johannsen G, Andersson AF, Yucel-Lindberg T. Identification of salivary microbiota and its association with host inflammatory mediators in periodontitis. Front Cell Infect Microbiol 2019;9:216. DOI |
17 | Bourgeois D, Inquimbert C, Ottolenghi L, Carrouel F. Periodontal pathogens as risk factors of cardiovascular diseases, diabetes, rheumatoid arthritis, cancer, and chronic obstructive pulmonary disease-is there cause for consideration? Microorganisms 2019;7:424. DOI |
18 | Kim TS, Kang NW, Lee SB, Eickholz P, Pretzl B, Kim CK. Differences in subgingival microflora of Korean and German periodontal patients. Arch Oral Biol 2009;54:223-9. DOI |
19 | Haffajee AD, Socransky SS. Microbial etiological agents of destructive periodontal diseases. Periodontol 2000 1994;5:78-111. DOI |
20 | Arenas Rodrigues VA, de Avila ED, Nakano V, Avila-Campos MJ. Qualitative, quantitative and genotypic evaluation of Aggregatibacter actinomycetemcomitans and Fusobacterium nucleatum isolated from individuals with different periodontal clinical conditions. Anaerobe 2018;52:50-8. DOI |
21 | Yun JH, Park JE, Kim DI, Lee SI, Choi SH, Cho KS, et al. Identification of putative periodontal pathogens in Korean chronic periodontitis patients. J Korean Acad Periodontol 2008;38:143-52. DOI |
22 | Bartold PM, Van Dyke TE. Host modulation: controlling the inflammation to control the infection. Periodontol 2000 2017;75:317-29. DOI |
23 | Bartold PM, Van Dyke TE. Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned concepts. Periodontol 2000 2013;62:203-17. DOI |
24 | Darveau RP, Tanner A, Page RC. The microbial challenge in periodontitis. Periodontol 2000 1997;14:12-32. DOI |
25 | Zhou X, Liu X, Li J, Aprecio RM, Zhang W, Li Y. Real-time PCR quantification of six periodontal pathogens in saliva samples from healthy young adults. Clin Oral Investig 2015;19:937-46. DOI |
26 | Rodenburg JP, van Winkelhoff AJ, Winkel EG, Goene RJ, Abbas F, de Graff J. Occurrence of Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in severe periodontitis in relation to age and treatment history. J Clin Periodontol 1990;17:392-9. DOI |
27 | Boutaga K, Savelkoul PH, Winkel EG, van Winkelhoff AJ. Comparison of subgingival bacterial sampling with oral lavage for detection and quantification of periodontal pathogens by real-time polymerase chain reaction. J Periodontol 2007;78:79-86. DOI |
28 | Socransky SS, Haffajee AD. Dental biofilms: difficult therapeutic targets. Periodontol 2000 2002;28:12-55. DOI |
29 | Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol 2005;43:5721-32. DOI |
30 | Umeda M, Contreras A, Chen C, Bakker I, Slots J. The utility of whole saliva to detect the oral presence of periodontopathic bacteria. J Periodontol 1998;69:828-33. DOI |
31 | Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y. Rapid detection and quantification of five periodontopathic bacteria by real-time PCR. Microbiol Immunol 2001;45:39-44. DOI |
32 | Teles RP, Patel M, Socransky SS, Haffajee AD. Disease progression in periodontally healthy and maintenance subjects. J Periodontol 2008;79:784-94. DOI |
33 | Tartaglia GM, Gagliano N, Zarbin L, Tolomeo G, Sforza C. Antioxidant capacity of human saliva and periodontal screening assessment in healthy adults. Arch Oral Biol 2017;78:34-8. DOI |
34 | Yoshida A, Suzuki N, Nakano Y, Oho T, Kawada M, Koga T. Development of a 5' fluorogenic nuclease-based real-time PCR assay for quantitative detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. J Clin Microbiol 2003;41:863-6. DOI |
35 | Paju S, Pussinen PJ, Suominen-Taipale L, Hyvonen M, Knuuttila M, Kononen E. Detection of multiple pathogenic species in saliva is associated with periodontal infection in adults. J Clin Microbiol 2009;47:235-8. DOI |