The antiplaque and bleeding control effects of a cetylpyridinium chloride and tranexamic acid mouth rinse in patients with gingivitis |
Lee, Ji-Eun
(Department of Periodontology, Kyungpook National University School of Dentistry)
Lee, Jae-Mok (Department of Periodontology, Kyungpook National University School of Dentistry) Lee, Youngkyun (Department of Biochemistry, Kyungpook National University School of Dentistry) Park, Jin-Woo (Department of Periodontology, Kyungpook National University School of Dentistry) Suh, Jo-Young (Department of Periodontology, Kyungpook National University School of Dentistry) Um, Heung-Sik (Department of Periodontology, Research Institute for Oral Sciences, Gangneung-Wonju National University College of Dentistry) Kim, Yong-Gun (Department of Periodontology, Kyungpook National University School of Dentistry) |
1 | Lindhe J, Hamp S, Loe H. Experimental periodontitis in the beagle dog. J Periodontal Res 1973;8:1-10. DOI |
2 | Loe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol 1965;36:177-87. DOI |
3 | Axelsson P, Lindhe J. The effect of a preventive programme on dental plaque, gingivitis and caries in schoolchildren. Results after one and two years. J Clin Periodontol 1974;1:126-38. DOI |
4 | Van der Weijden FA, Van der Sluijs E, Ciancio SG, Slot DE. Can chemical mouthwash agents achieve plaque/gingivitis control? Dent Clin North Am 2015;59:799-829. DOI |
5 | Serrano J, Escribano M, Roldan S, Martin C, Herrera D. Efficacy of adjunctive anti-plaque chemical agents in managing gingivitis: a systematic review and meta-analysis. J Clin Periodontol 2015;42 Suppl 16:S106-38. DOI |
6 | Loe H, Schiott CR, Karring G, Karring T. Two years oral use of chlorhexidine in man. I. General design and clinical effects. J Periodontal Res 1976;11:135-44. DOI |
7 | Haps S, Slot DE, Berchier CE, Van der Weijden GA. The effect of cetylpyridinium chloride-containing mouth rinses as adjuncts to toothbrushing on plaque and parameters of gingival inflammation: a systematic review. Int J Dent Hyg 2008;6:290-303. DOI |
8 | Gunsolley JC. Clinical efficacy of antimicrobial mouthrinses. J Dent 2010;38 Suppl 1:S6-10. DOI |
9 | Dunn CJ, Goa KL. Tranexamic acid: a review of its use in surgery and other indications. Drugs 1999;57:1005-32. DOI |
10 | Sindet-Pedersen S. Distribution of tranexamic acid to plasma and saliva after oral administration and mouth rinsing: a pharmacokinetic study. J Clin Pharmacol 1987;27:1005-8. DOI |
11 | Borea G, Montebugnoli L, Capuzzi P, Magelli C. Tranexamic acid as a mouthwash in anticoagulant-treated patients undergoing oral surgery. An alternative method to discontinuing anticoagulant therapy. Oral Surg Oral Med Oral Pathol 1993;75:29-31. DOI |
12 | Axelsson P, Lindhe J. Efficacy of mouthrinses in inhibiting dental plaque and gingivitis in man. J Clin Periodontol 1987;14:205-12. DOI |
13 | Ramstrom G, Sindet-Pedersen S, Hall G, Blomback M, Alander U. Prevention of postsurgical bleeding in oral surgery using tranexamic acid without dose modification of oral anticoagulants. J Oral Maxillofac Surg 1993;51:1211-6. DOI |
14 | Sindet-Pedersen S, Ramstrom G, Bernvil S, Blomback M. Hemostatic effect of tranexamic acid mouthwash in anticoagulant-treated patients undergoing oral surgery. N Engl J Med 1989;320:840-3. DOI |
15 | Fischman SL. Clinical index systems used to assess the efficacy of mouthrinses on plaque and gingivitis. J Clin Periodontol 1988;15:506-10. DOI |
16 | Shim JY, Yim SB, Chung JH, Hong KS. Antiplaque and antigingivitis effects of a mouthrinse containing cetylpyridinium chloride, triclosan and dipotassium glycyrrhizinate. J Periodontal Implant Sci 2012;42:33-8. DOI |
17 | White DJ. An alcohol-free therapeutic mouthrinse with cetylpyridinium chloride (CPC)--the latest advance in preventive care: Crest Pro-Health Rinse. Am J Dent 2005;18 Spec No:3A-8A. |
18 | Kozak KM, Gibb R, Dunavent J, White DJ. Efficacy of a high bioavailable cetylpyridinium chloride mouthrinse over a 24-hour period: a plaque imaging study. Am J Dent 2005;18 Spec No:18A-23A. |
19 | Gunsolley JC. A meta-analysis of six-month studies of antiplaque and antigingivitis agents. J Am Dent Assoc 2006;137:1649-57. DOI |
20 | Stookey GK, Beiswanger B, Mau M, Isaacs RL, Witt JJ, Gibb R. A 6-month clinical study assessing the safety and efficacy of two cetylpyridinium chloride mouthrinses. Am J Dent 2005;18 Spec No:24A-28A. |
21 | Van der Weijden GA, Timmerman MF, Nijboer A, Reijerse E, Van der Velden U. Comparison of different approaches to assess bleeding on probing as indicators of gingivitis. J Clin Periodontol 1994;21:589-94. DOI |
22 | Carter G, Goss A, Lloyd J, Tocchetti R. Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: a randomized prospective clinical study. J Oral Maxillofac Surg 2003;61:1432-5. DOI |
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