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http://dx.doi.org/10.5051/jpis.2014.44.6.293

Oral signs of acute leukemia for early detection  

Lim, Hyun-Chang (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Kim, Chang-Sung (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Publication Information
Journal of Periodontal and Implant Science / v.44, no.6, 2014 , pp. 293-299 More about this Journal
Abstract
Purpose: Systemic disease can manifest oral signs at an early phase, which may be crucial for the diagnosis and timing of treatment. This report describes two patients who presented with gingival enlargement as an early sign of acute leukemia. Methods: Two patients presented with oral symptoms including severe gingival enlargement. The progress of their symptoms was associated with underlying systemic disease. Results: The patients were transferred to the Department of Hematology and diagnosed with acute myelomonocytic leukemia. They received appropriate treatment and survived. Conclusions: Gingival enlargement can be caused by underlying systemic diseases. Accurate diagnosis and timely referral are important for preventing a fatal situation. It must be emphasized that some oral signs and symptoms may be closely correlated with systemic diseases.
Keywords
Dentist; Gingival hyperplasia; Leukemia;
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