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http://dx.doi.org/10.5051/jpis.2011.41.5.242

The effect of fibronectin-coated implant on canine osseointegration  

Kim, Sung-Tae (Department of Prosthodontics, Yonsei University College of Dentistry)
Myung, Woo-Chun (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Lee, Jung-Seok (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Cha, Jae-Kook (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Jung, Ui-Won (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Yang, Hyeong-Cheol (Department of Dental Biomaterials Science and Dental Research Institute, Seoul National University School of Dentistry)
Lee, In-Seop (Institute of Physics and Applied Physics, Atomic-Scale Surface Research Center, Yonsei University)
Choi, Seong-Ho (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
Publication Information
Journal of Periodontal and Implant Science / v.41, no.5, 2011 , pp. 242-247 More about this Journal
Abstract
Purpose: The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface. Methods: Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluation after 4- and 8-week healing periods. Results: All types of implants were clinically stable without any mobility. Although the bone-to-implant contact and bone density of the SLA implants coated with calcium phosphate (CaP)/fibronectin were lower than the uncoated SLA implants, there were no significant differences between the uncoated SLA surface group and the SLA surface coated with CaP/fibronectin group. Conclusions: Within the limits of this study, SLA surfaces coated with CaP/fibronectin were shown to have comparable bone-to-implant contact and bone density to uncoated SLA surfaces.
Keywords
Biocompatible coated materials; Bone density; Calcium phosphate; Dental implants; Fibronectins;
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