Browse > Article

The comparative study - the regenerative effect depends on size of bone graft material in bone loss site around dental implant  

O, Hong-Kyun (Department of Periodontology, School of Dentistry, Dan Kook University)
Hong, Ki-Seok (Department of Periodontology, School of Dentistry, Dan Kook University)
Chung, Chin-Hyung (Department of Periodontology, School of Dentistry, Dan Kook University)
Yim, Sung-Bin (Department of Periodontology, School of Dentistry, Dan Kook University)
Publication Information
Journal of Periodontal and Implant Science / v.38, no.3, 2008 , pp. 493-502 More about this Journal
Abstract
Purpose: The purpose of this study is to investigate on the regenerative capacity by using different size of graft materials around bony defect around implant. Material and Methods: Dental implant fixtures(Bio-TIS, Korea) were placed into the tibia of 8 rabbits. After placement of implant, artificial defects were created for each group, and the size of bone graft materials were used according to each designated group. 4 weeks after surgery, 8 rabbits were sacrificed. The histologic and histomorphometrical study were done for comparison of the regenerative capacity using $80-90{\mu}m$ and $200{\sim}1000{\mu}m$ size of grafting materials of OCS-$B^{(R)}$. Result: Matured bone formation was significantly increased more in Group E1($80-90{\mu}m$) than in Group E2($200{\sim}1000{\mu}m$). Group E1($80-90{\mu}m$) showed more significant augmentation in marginal length of graft material per unit area than Group E2($200{\sim}1000{\mu}m$). Group E1($80-90{\mu}m$) showed more interspace in graft material than Group E2($200{\sim}1000{\mu}m$). Control group showed no new bone formation around and inside of implanted fixture. Conclusion: Small grafting material size has great influence on bone regeneration.
Keywords
Regenerative capacity; dental implant defect; Bone graft materials;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Fugazzotto PA, Shanaman R, Manos T, Shectman R. Guided Bone regeneration around titanium implants: Report of the treatment of 1,503 sites with clinical reentries. Int J Periodontics Restorative Dent 1997;17:292-299   PUBMED
2 Melcher AH, Accursi GE. Osteogenic capacity of periosteal and osteo-periosteal flaps elevated from parietal bone of the rat. Arch Oral Biol 1971;16:573-580   DOI   ScienceOn
3 Gottlow J, Nyman S, Karring T, Lindhe J. New attachment formation as the result of controlled tissue regeneration. J Clin Periodontol 1984;11:494-503   DOI
4 Uchida A, Nade SM, McCartney ER, Ching W. The use of ceramics for bone replacement. A comparative study of three defferent porous ceramics. J Bone Joint Surg Br 1984;66:269-275   DOI   PUBMED
5 Clokie CML, Sandor GKB. Bone. present and future. In: Babbush CA. Dental implants: the art and science. Philadelphia: W.B. Sanduers Company; 2001;70
6 John HD, Wenz B. Histomorphometric analysis of natural bone mineral for maxillary sinus augmentation. Int J Oral Maxillofac Implants 2004;19:199-207
7 Norton MR, Odell EW, Thompson ID, Cook RJ. Efficacy of bovine bone mineral for alveolar augmentation: a human histologic study. Clin Oral Implants Res 2003;14:775-783   DOI   ScienceOn
8 Schallhorn RG, Hiatt WH, Boyce W. Iliac transplants in periodontal therapy. J Periodontol 1970;41(10):566-580   DOI   PUBMED
9 Wenz B, Oesch O, Horst M. Analysis of the risk of transmitting bovine spongiform encephalopathy through bone grafts derived from bovine bone. Biomaterials 2001;22: 1599-1606   DOI   ScienceOn
10 Schallhorn RG, Hiatt WH. Human allografts of iliac cancellous bone and marrow in periodontal osseous defects I. Rationale and methodology. J Periodontol 1971;42(10):642-647   DOI   PUBMED
11 Mellonig JT. Human histologic evaluation of a bovine-derived bone xenograft in the treatment of periodontal osseous defects. Int J Periodontics Restorative Dent. 2000;20: 19-29
12 Lazzara R. Immediate implant placement into extraction sites: Surgical and restorative advantages. Int J Periodontics Restorative Dent 1989;9:333-343
13 Dahlin C, Alberius P, Lindhe A. Osteopromotion for cranioplasty. An experimental study in rats using a membrane technique. J Neurosurg 1991;74:487-491   DOI
14 Becker W, Becker BE, Handlesman M et al. Bone formation at dehisced dental implant sites treated with implant augmentation material: A pilot study in dogs. Int J Periodont Rest Dent 1990;10:93-101
15 Sculean A, Chiantella GC, Windisch P et al. Healing of intra-bony defects following treatment with a composite bovine-derived xenograft(Bio-Oss Collagen) in combination with a collagen membrane (Bio-Gide PERIO). J Clin Periodontal 2005;32:720-724   DOI   ScienceOn
16 Vincente JC, Lopez-Arranz JS. Tissue regeneration in bone defects adjacent to endosseous implants: An experimental pilot study. Int J Periodontics Restorative Dent 2000;20: 41-49
17 Nevins M, Mellonig JT. The advantages of localized ridge augmentation prior to implant placement: A staged event. Int J Periodontics Restorative Dent 1994;14:97-111
18 Becker W, Lynch SE, Lekholm U et al. A comparison of three methods for promoting bone formation around implant placed into immediate extraction sockets: e-PTFE membrane alone or with either PDGF and IGF-1 or DFDB. J Periodontol 1992;63:929-940   DOI   PUBMED
19 Chang RC, Kao AS. Biomechanical and histological studies of particulate hydroxyapatite implanted in femur bone defects of adult dogs. Int J Oral Maxillofac Surg 2000;29: 54-56   DOI   ScienceOn
20 Dahlin C, Andersson L, Lindhe A. Bone augmentation at fenestrated implants by an osteopromotive membranetechnique. A controlled clinical study. Clin Oral Implants Res 1991;2:159-165   DOI   ScienceOn
21 Piattelli M, Favero GA, Scarano A, Orsini G, Piattelli A. Bone reactions to anorganic bovine bone (Bio-Oss) used in sinus augmentation procedures: a histologic long-term report of 20 cases in humans. Int J Oral Maxillofac Implants 1999;14:835-840
22 Uchida A, Nade SM, McCartney ER, Ching W. Growth of bone marrow cells on porous ceramics in vitro. J Biomed Mater Res 1987;21:1-10   DOI   ScienceOn
23 Buser D, Dula K, Belser U, Hirt H-P, Schenk RK. Lateral ridge augmentation using autografts and barrier membranes: A clinical study with 40 partially edentulous patients. J Oral Maxillofac Surg 1996;54:420-422   DOI   ScienceOn
24 Becker W, Becker BE. Guided tissue regeneration for implants placed into extraction sockets and for implant dehiscences: Surgical techniques and case reports. Int J Periodontics Restorative Dent 1990;10:377-391
25 Strub JR, Gaberthuel TW, Firestone AR. Comparison of tricalcium phosphate and frozen allogenic bone implants in man. J Periodontol 1979;50:624-629   DOI   PUBMED
26 Buser D, Dula K, Belser U, Hirt H-P, Berthold H. Localized ridge augmentation using guided bone regeneration. I. Surgical procedure in the maxilla. Int J Periodontics Restorative Dent 1993;13:29-45   PUBMED
27 Sartori S, Silvestri M, Forni F, Icaro Cornaglia A, Tesei P, Cattaneo V. Ten-year follow-up in a maxillary sinus augmentation using anorganic bovine bone (Bio-Oss). A case report with histomorphometric evaluation. Clin Oral Implants Res 2003;14:369-372   DOI   ScienceOn
28 Vaccaro AR. The role of the osteoconductive scaffold in synthetic bone graft. Orthopedics 2002;25:571-578
29 Aiorana C, Redemagni M, Rabagliati M, Salina S. Treatment of maxillary ridge resorption by sinus augmentation with iliac cancellous bone, anorganic bovine bone, and endosseous implants: a clinical and histologic report. Int J Oral Maxillofac Implants 2000;15:873-878
30 Dahlin C, Sennerby L, LekholmU, Linde A, Nyman S. Generation of new bone around titanium implants usinga membrane technique: An experimental study in rabbits. Int J Oral Maxillofac implants 1989;4:19-25   PUBMED
31 Landi L, Pretel RW Jr, Hakimi NM, Setayesh R. Maxillary sinus floor elevation using a combination of DFDBA and bovine-derived porous hydroxyapatite: a preliminary histologic and histomorphometric report. Int J Periodontics Restorative Dent 2000;20:574-583   PUBMED
32 Hallman M, Sennerby L, Zetterqvist L, Lundgren S. A 3-year prospective follow-up study of implant-supported fixed prostheses in patients subjected to maxillary sinus floor augmentation with a 80:20 mixture of deproteinized bovine bone and autogenous bone Clinical, radiographic and resonance frequency analysis. Int J Oral Maxillofac Surg 2005;34:273-280   DOI   ScienceOn
33 Froum SJ, Tarnow DP, Wallace SS, Rohrer MD, Cho SC. Sinus floor elevation using anorganic bovine bone matrix (OsteoGraf/N) with and without autogenous bone: a clinical, histologic, radiographic, and histomorphometric analysis- Part 2 of an ongoing prospective study. Int J Periodontics Restorative Dent 1998;18:528-543   PUBMED