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Clinical study on therpeutic effects of Guided tissue regeneration by $Nanogide-C^{(R)}$ and $Biomesh^{(R)}$ in furcation defects  

Han, Kyung-Hee (Department of Periodontology, School of Dentistry, Wonkwang University)
Jung, Jong-Won (Department of Periodontology, School of Dentistry, Wonkwang University)
Hyun, Ha-Na (Department of Periodontology, School of Dentistry, Wonkwang University)
Kim, Ji-Man (Department of Periodontology, School of Dentistry, Wonkwang University)
Kim, Yun-Sang (Department of Periodontology, School of Dentistry, Wonkwang University)
Pi, Sung-Hee (Department of Periodontology, School of Dentistry, Wonkwang University)
Shin, Hyung-Shik (Department of Periodontology, School of Dentistry, Wonkwang University)
Publication Information
Journal of Periodontal and Implant Science / v.35, no.4, 2005 , pp. 877-889 More about this Journal
Abstract
This study was designed to compare the effects of treatment using chitosan membrane $(Nanogide-C^{(R)})$ resorbable barrier with control treated by polylactic acid/polylacticglycolic acid membrane(PLA/PLGA membrane, $Biomesh^{(R)}$). 44 furcation defecs from 44 patients with class 2 furcation degree were used for this study, 22 sites of them were treated by chitosan membrane as experimental group and 22 site were treated by PLA/PLGA membrane as control group. Clinical parameters including probing depth, gingival recession, attachment level and radiographic examination were evlauated at base line, 1 month, 2 month and 3 month. after surgery. Statistical test used to analyze these data included paired t-test, one way ANOVA. The results are as follows : 1. Probing depth was significanlly decreased in the two group and there were significant differences between groups(p<0.05). 2. Gingival recession was not significanlly increased in the two group and there were no significant differences between groups(p<0.05). 3. Loss of attachment was statistically decreased in the two group and there were no significant differences between groups(p<0.05). 4. Horizontal bone level was significanlly increased in the two group and there were significant differences between groups(p<0.05). On the basis of these results, chitoans resorbable membrane has similar potential to PLA/PLGA membrane in GTR for furcation defect.
Keywords
chitosan membrane; PLA/PLGA; furcation involvement; GTR;
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