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Amlodipine-induced gingival overgrowth around dental implants  

Yoo, Jang-Bae (Department of Dentistry, College of Medicine, Inha University)
Kim, Il-Kyu (Department of Dentistry, College of Medicine, Inha University)
Choi, Jin-Ho (Department of Dentistry, College of Medicine, Inha University)
Lee, Jae-Kwan (Department of Periodontology, College of Dentistry, Kangnung National University)
Um, Heung-Sik (Department of Periodontology, College of Dentistry, Kangnung National University)
Chang, Beom-Seok (Department of Periodontology, College of Dentistry, Kangnung National University)
Publication Information
Journal of Periodontal and Implant Science / v.35, no.3, 2005 , pp. 591-596 More about this Journal
Abstract
Amlodipine, nifedipine, and felodipine are calcium channel blocking agents, which are cause of unwanted gingival overgrowth around natural teeth. Many studies has been performed about this unwanted effects. However, the exact etiology remains uncertain.Few reports and investigations can be found in the literature on drug-induced gingival overgrowth around dental implants. The present case reports that amlodipine-induced gingival overgrowth occurred in peri-implant sites, confirms clinical and histological features in hyperplastic peri-implant tissues. Clinical and histological features of amlodipine-induced gingival overgrowth around dental implants were similar to that of tissue around natural teeth.
Keywords
Calcium channel blocking agents; amlodipine; Gingival hyperplasia; Peri-implant tissue;
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