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The effects of microcrystalline hydroxyapatite containing toothpaste in the control of tooth hypersensitivity  

Park, Jung-Ju (Department of Periodontology, Kyung Hee University)
Park, Joon-Bong (Department of Periodontology, Kyung Hee University)
Kwon, Young-Hyuk (Department of Periodontology, Kyung Hee University)
Herr, Yeek (Department of Periodontology, Kyung Hee University)
Chung, Jong-Hyuk (Department of Periodontology, Kyung Hee University)
Publication Information
Journal of Periodontal and Implant Science / v.35, no.3, 2005 , pp. 577-590 More about this Journal
Abstract
The purpose of this study was to evaluate the effects of toothpaste containing hydroxyapatite for patients who complained dental hypersensitivity. Before baseline of application of toothpaste with hydroxyapatite, tooth brushing instruction was done respectively and the several indices were measured at baseline, 2, 4, 8 weeks. Clinical indices were estimated, and responses to cold, compressive air, tactile stimulus were evaluated with verbal rating score. Relief effects and visual analogue scale were also evaluated. The results of this study were as follows 1. The occurrence rate of hypersensitivity in upper jaw was higher than that of lower jaws, and molar area showed more hypersensitivity than premolar and incisor area. Buccal site was hypersensitive followed by interproximal and lingual site. 2. Plaque index, gingival index and probing depth reduction were gradually improved after Tooth Brushing Instruction and using toothpaste. 3. Subjects showed most sensitive response to cold stimuli than compressive air and tactile stimuli. 4. The relief effect was increased during using tooth paste and complete relief was increased especially at 8 weeks. 5. Visual analogue scale was increased. In conclusion, it was confirmed that toothpaste containing microcrystalline hydroxyapatite have the relief effect of tooth hypersensitivity. During 8 weeks, stimulus responses were decreased and hypersensitivity relief effect was increased.
Keywords
microcrystalline hydroxyapatite toothpaste; hypersensitivity;
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1 Lukomsky EH. Fluoride therapy for exposed dentin and alveolar atrophy. J Dent Res 1941:20:649-655   DOI
2 Minkoff S, Axelrod S. Efficacy of strontium chloride in dentinal htpersensitivity. J Periodontol 1987:58:470-474   DOI   PUBMED
3 Shapiro WB, Kaslick R., Chasens AI. The effect of a strontium chloride toothpaste on root hypersensitivity in a controlled clinical stud., J Periodontol 1970: 42:702-703
4 Hiatt WH, Johansen E. Root preparation I. Obturation of dentinal tubules in treatment of root hypersensitivity. J Periodontol 1972:43:373   DOI   PUBMED
5 Tarbe WJ, Silverman G, Stolman JM. An evaluation of two methods for the quantification of dentinal hypersen-sitivity. J Am Dent Assoc 1979:98:914-918   PUBMED
6 Addy M, Absi EG, Adams D. Dentin hypersensitivity. The effects in vitro of acids and ditetary substances on root planed and buried dentin. J Clin Periodontol 1987: 14:274-279   DOI   PUBMED
7 Ash MM. Qualification of stimuli. Endodont Dent Traumatol 1986:2: 153-156   DOI
8 Addy M. Mostofa P. Dentine hypersensitivity. II. Effects produced by the uptake in vitro of toothpastes onto dentine. J Oarl Rehab 1989; 16:35-48   DOI
9 Aoki H. Shimura N. Kuboki Y. Plaque and hydroxyapatite. Dent J 1982: 15:463
10 Pashley DB. Dentin permeability, dentin sensitivity, amd treatment through tubule occlusion. J Endodont 1986: 12:465-474   DOI   PUBMED   ScienceOn
11 Pashley DH, Leibach JG, Horner JA. The effects of burnishing NaF/Kaolin/ Glycerine paste on dentin permeability. J Periodontol 1987:58:19   DOI   PUBMED
12 Karlsson UL, Penny DA. Natural desensitization of exposed tooth roots in dogs. J Dent Res 1975:54:982   DOI   PUBMED   ScienceOn
13 Greenhill JD, Pashley D. The effects of desensitising agents on the hydraulic conductance of dentin in vitro. J Dent Res 1981:60:686   DOI   PUBMED   ScienceOn
14 Renton-Harper P, Midda M. Nd: Yag laser treatment of dentinal hypersensitivity. Br Dent J 1992; 117: 13-16
15 Gangarosa LP. Iontophretic application of fluoride by tray techniques for desensitisation of multiple teeth. J Am Dent Assoc 1981: 102: 50-52   PUBMED
16 Zinner DD, Duanny LF, Lutz HJ. A new desensitising dentifrice: preliminary report. J Am Dent Assoc 1977:95:982-985   PUBMED
17 Huskisson EC. Visual Analogue scales in Melzack R(ed) : Pain measurements and Assesmant. New york, Raven Press, 1983
18 신혜련, 이만섭, 권영혁. 치주수술 후 노출된 치근에서 발생하는 지각과민증의 발생양태에 관한 연구. 대한치주과학회지 1998: 18: 174-185
19 Addy M. Etiology and clinical implication of dentine hypersensitivity. Dent Clin North Am 1990:34:503-514   PUBMED
20 Graf H, Galasse R. Morbidity, prevalence and intraoral distribution of hypersensitive teeth. J Dent Res 1977:56 (Special Issue A): 162
21 Addy M, Dowell P. Dentine hypersensitivity-A review, Clinical and in vitro evaluation of treatment agent. J Clin Periodontol 1983:10:351-363   DOI   PUBMED
22 Sowinsk J, Ayad F, Petrone M, DeVizio W, Volpe A. Ellwood R, Davies R. Comparative investigations of the desensitising efficacy of a new dentifrice. J Clin Periodontol 2001:28: 1032-1036   DOI   ScienceOn
23 Kanapka JA. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. Review of clinical studies. Dent Clin North Am 1990:34:545-560   PUBMED
24 Bender IE. Pain conference surmmary. J Endodont 1986: 12:509   DOI   ScienceOn
25 Green B, Green M, Mcfall J. Calcium hydroxide and potassium nitrate as desensitising agents for hypersensitive root surface. 1977:48:667-672   DOI   PUBMED
26 Wannenmacher E. Untersuchungen zur wirkung der zahncreme : 'Zanmed'. Munster W. G, 1973
27 Clark DC, Al-joburi W, Chan ECS. The efficacy of a new dentifrice in treating dentin sensitivity: Effects of sodium citrate and sodium fluoride as active ingredients. J Periodontol Res 1987:22:89-93   DOI   PUBMED
28 Kuboki Y. Tazaki M. Mizuno M. Fujita K. Demineralization. remineral-ization and microfilling restoration of enamel surface. Dent J 1987:26:215
29 Levin M. Yerwood LL, Carpenter WN. The desensitising effect of calcium hydroxide and magnesium hydroxide on hypersensitive dentine. Oral Surgery 1973; 35: 649-659   DOI   ScienceOn
30 Hyot WH, Bibby BG. Use of sodium fluoride for desentizing dentin. J Am Dent Assoc. 1943;30: 1372-1376
31 Cuesta FS, Menendez M, Guisasola C, Arregui I. Tejerina JM, Sicilia A. Evaluation of the efficacy of two potassium nitrate bioadhesive gels(5% and 10%) in the treatment of dentine hypersensitivity. A randomised clinical trial. J Periodontol 2003:30:315-320   DOI   ScienceOn
32 Clark GE. Troullos ES. Designing hypeersensitivity, Clinical studies. Dent Clin North Am 1990:34:531-544   PUBMED
33 Shimura N. Onisi M. The effect of NaF on the bacterial production of polysaccaride and subsequent adsortion on hydroxyapatite. J Dent Res 1978;57:928   DOI   PUBMED   ScienceOn
34 Bal J and Kundalgurki. Tooth sensitivity, Prevention and treatment. Oral Health 1999:33-41   PUBMED
35 Miller JT, Shannon I. kilgore W, Bookman J. Use of a water-free stannous fluoride containing gel in the control of dentinal hypersensitivity. J Periodontol 1969; 40 :490-491   DOI   PUBMED
36 Newman WF, Bjorneeerstedt R, Mulryan BJ. Synthetic hydroxyapatite crystals II. Aging and strontium incorporation. Arch Biochem Biophys 1963: 101:215   DOI
37 Tarbet WJ, Silverman G, Fratarcangelo PA. Home treatment for dentinal hypersensitivity. A comparative study. J Am Dent Assoc 1982: 105: 227   PUBMED
38 Pashley DH. The dentin-predentin complex and its permeability: Physiologic overview. J Dent Res 1985:64(special issue): 613-20   PUBMED
39 Schaeffer ML, Bixler D, Yu PL. The effectiveness of iontophoresis in reducing cervical hypersensitivity. J Periodontol 1971;42:695-700   DOI   PUBMED
40 Minkov B, Marmari I. Gedalia I. Garfunkel A. The effectiveness of sodium fluoride treatment with and without iontophoresis on the reduction of hypersensitive dentine. J Periodontol 1975;46 :246-249   DOI   PUBMED
41 Dachi SF. The relationship of pulpitis and hyperemia to the thermal sensitivity. Oral Surg 1965: 19: 776   DOI   ScienceOn
42 Gershman JA Ruben J, Gebart-Eaglemont J. Low level laser for dentinal tooth hypersensitivity. Aust. Dent. J 1994:39:353-357   DOI   ScienceOn
43 Kani T. Kani M. Isozaki A. Shintani H. Ohashi T. Tokumoto T. Effect to apatite-containg dentifrices on dental caries in school children. J dent Hlth 1989;39: 104-109   DOI
44 Hodge HC, Gavett E, Thomas I. The adsorption of strontium at forty degrees by enamel, dentin, bone and hydroxyapatite as shown by the radioactive isotope. J Biol. Chem, 1946: 163: 1
45 Pereira R, Chava VK. Efficiency of a 3% potassium nitrate desensitizing mouthwash in the treatment of dentinal hypersensitivity. J Periodontol 2001:72:1720-1725   DOI   ScienceOn
46 Orchardson R. Collins WJN. Clinical features of hypersentive teeth teeth. Br Dent J 1987: 162:253   DOI   ScienceOn
47 Tarbet WJ., Silverman G, Stolman JM, Fratarcangelo. Clinical evaluation of a new treatment for dentinal hypersensitivity. J Periodontol 1980:51:535-540   DOI   PUBMED
48 Loe & Silness. Periodontal disease in pregnancy, I .Prevalence and severity. Acta Odont Scand 1963:21:533   DOI   ScienceOn
49 Collins JF, Gingold J, Stanley H. Reducing dentinal hypersensitivity with strontium chloride and potassium nitrate. Gen Dent 1984:32:40-43   PUBMED
50 Wycoff SJ. Current treatment for dentinal hypersensitivity. Compendium 1982: (Suppl) 3:s113
51 Fisher CB. Dentine hypersensitivity. a review. Endod Dent Traumatol 1991: 7 : 145-152   DOI   PUBMED
52 Mior IA. Human coronal dentine: structure and reactions. Oral Surg, 1972: 33: 810   DOI   ScienceOn
53 Hutteman RW. Strubel G. Rzekpa-Glinder V. Donges H. Investigation of utility and mechnics of use of hydroxyapatite for therapy of htper-sensitive tooth root. ZWR. 1989;98:240-245   PUBMED
54 Imai Y, Akimoto T. A new method of treatment for dentin hypersensitivity by precipitation of calcium phosphate in situ. Dental Materials Journal 1990:9(2) : 167-172   DOI   PUBMED   ScienceOn
55 Hernandez F, Mohammed C, Shannon I. Clinical study evaluating the desensitizing effect and duration of two commercially available dentifrice, J Periodontol 1972:43: 367   DOI   PUBMED
56 Hodash M. A superior desensitizer. J Am Dent Assoc 1974;88:831   PUBMED
57 Silness & Löe. Periodontal disease in pregnancy, II. Correlation between oral hygiene and periodontal condition. Acta Odont Scand 1964:22: 121   DOI   ScienceOn
58 Gorman WJ. Prevalence and etiology of gingival recession. J Periodontol 1967: 38 :316   PUBMED
59 Ong G, Strahan JD. Effect of a desensitizing dentifrice on dental hypersensitivity. Endod Dent Traumatol. 1989:5:213-218   DOI
60 김종헌, 김선욱, 권영혁, 이만섭: 미세결정형 수산화인회석 함유치약의 상아질 지각과민증상 완화효과에 관한 임상적 연구. 대한치주과학회지, 1984: 14:229-240
61 Pashley DH. Smear layer: Physiological consideration. Oper Dent 1984:3: 13-29
62 Barone M. Malpassi M. Clinical trial of a 15% supermicronized hydroxya-patite gel for dentin hypersensitivity. G Ital Endod 1991:5:43-47   PUBMED
63 Bergenholtz G and Reit C. Reactions of the dental pulp to microbial provocation of calcium hydroxide treated dentin. Scand J Dent Res 1980;88: 187   PUBMED
64 Trowbridge H. Silver DR. A review of current approaches to in-office management of tooth hypersensitivity. Dent Clin North Am 1990:34: 561-581   PUBMED
65 임상철, 최진근, 허익, 이만섭: 치주질환 치료후 미세결정형 수산화인회석 함유치약의 지각과민억제 효과에 관한 임상적 연구. 대한치주과학회지 1993;23:127-134
66 Kern DA. McQuade MJ, Scheidt MJ, Hanson B, Van Dyke TE. Effectiveness of sodium fluoride on tooth hypersensitivity with and without iontophoresis. J Periodontol 1989; 60: 386-389   DOI   PUBMED
67 Uchida A., Wakano Y, Fukuyama O, Miki T, Iwayama Y, Okada H. Controlled clinical evaluation of a 10% strontium chloride dentifrice in treatment of dentin hypersensitivity following periodontal surgery. J Periodontol 1980:51:578-581   DOI   PUBMED
68 Brännström M, Johnson G, Nordenvall KJ. Transmission and control of dentinal pain: resin impregnation of the desensitization of dentin. J Am Dent Assoc 1979 :99:612   PUBMED
69 Murthy KS, Talim ST, Singh I. A comparative evaluation of topical application and iontophoresis of sodium fluoride for desensitisation of hypersensitive dentine. Oral surgery 1973:36:448-58   DOI   ScienceOn
70 Ohashi T. Kani T. Isozaki A. Nishida A. Shintani H. Tokumoto T. Ishizu E. Kuwahara Y, Kani M. Remineralization of artificial caries lesions by hydroxyapatite. J dent Hlth 1991:41:214-223   DOI
71 Addy M. Mostafa P, Newcombe R. Dentine hypersensitivity: A comparison of five toothpastes used during a 6 week treatment period. Br Dent J 1987: 163:45   DOI   ScienceOn