Antimicrobial and anti-gingivitis effect of chewing gum containing grapefruit seed extract and xylitol |
Jin, Mi-Sung
(Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science)
Yoo, Yun-Jung (Department of Oral Biology and Oral Science Research Center, College of Dentistry, Yonsei University) Choi, Bong-Kyu (Oromaxillofacial Infection and Immunity, College of Dentistry, Seoul National University) Lee, Hee-Young (Department of Oral Biology and Oral Science Research Center, College of Dentistry, Yonsei University) Kim, Mi-Jung (Department of Oral Biology and Oral Science Research Center, College of Dentistry, Yonsei University) Roh, Hoe-Jin (Tongyang Confectionery Corp. R&D Center) Park, Jong-Sub (Tongyang Confectionery Corp. R&D Center) Cho, Kyoo-Sung (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science) Kim, Chong-Kwan (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science) Choi, Seong-Ho (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science) |
1 | Hanham A, Addy M. The effect of chewing sugar-free gum on plaque regrowth at smooth and occlusal surfaces. J Clin Periodontol 2001;28:255-257 DOI ScienceOn |
2 | Schiele AA, Fejerskov O, Danielsen B. The effect of xylitol-containing chewing gums on dental plaque and acidogenic potential. J Dent Res 1998;77:1547-1552 DOI ScienceOn |
3 | Rauha JP, Remes S, Heinonen M, Hopia A, Kahkonen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P. Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. Int J Food Microbiology 2000;56:3-12 DOI ScienceOn |
4 | Chen Y, Zheng R, Jia Z, Ju Y. Flavonoids as superoxide scavengers and antioxidants. Free Radical Biology& Medicine 1990;9:19-21 PUBMED |
5 | Lee CH, Jeong TS, Choi YK, Hyun BH, Oh GT, Kim EH, Kim JR, Bok SH. Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and Aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits. Biochemical and Biophysical Research Communications 2001;284:681-688 DOI ScienceOn |
6 | 유윤정, 박용석, 곽월아, 조장기, 장희순, 권호근, 이승일. 자몽씨, 결명자 및 당귀에 의한 Streptococcus mutans의 증식억제 효과. 대한구강보건학회지 1995;19(3):357-372 |
7 | Simons D, Kidd EAM, Beighton D, Jones B. The effect of chlorhexidine/xylitol chewing-gum on cariogenic salivary microflora: a clinical trial in elderly patients. Caries Res 1997;31:91-96 DOI ScienceOn |
8 | Soderling E, Makinen KK, Chen CY, Pape HR Jr., Loesche W, Makinen PL. Effect of sorbitol, xylitol, and xylitol/sorbitol chewing gums on dental plaque. Caries Res 1989;23:378-384 DOI ScienceOn |
9 | Trahan L, Bareil M, Gauthier L, Vadeboncoeur C. Transport and phosphorylation of xylitol by a fructose phosphotransferase system in Streptococcus mutans, Caries Res 1985;15:53-63 |
10 | Hildbrandt GH, Sparks BS. Maintaining Mutans Streptococci suppression with xylitol chewing gum. JADA 2000;131:909-916 |
11 | Jagetia GC, Reddy TK. The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow : a micronucleus study. Mutation Research 2002;519:37-48 DOI |
12 | Smith AJ, Moran J, Dangler LV, Leight RS, Addy M. The efficacy of an anti-gingivitis chewing gum. J Clin Periodontol 1996;23:19-23 DOI PUBMED |
13 | Borrelli F, Izzo AA. The plant kingdom as a source of anti-ulcer remedies. Phytotherapy Research 2000;14:581-591 DOI ScienceOn |
14 | Read MA. Flavonoids: Naturally occurring anti-inflammatory agents. American J of Pathology 1995;147:235-237 |
15 | Tirillini B. Grapefruit: the last decade acquisitions. Fitoterapia 2000;71:S29-S37 DOI ScienceOn |
16 | Reageor L, Gusman J, McCoy L, Carino E, Heggers JP. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: I. An In Vitro Agar Assay. J Altrn Complement Med 2002;8:325-332 DOI ScienceOn |
17 | Hrimech M, Mayrand D, Grenier D, Trahan L. Xylitol disturbs protein synthesis, including the expression of HSP-70 and HSP-60, in Streptococcus mutans, Oral Microbiol Immunol 2000;15:249-257 DOI ScienceOn |
18 | 배광학, 노승학, 문혁수. 트리클로잔과 자몽종자 추출물(GFSE)과 Eucalyptus oil 및 플라보노이드를 배합한 세치제의 구취예방효과에 관한 연구. 대한구강보건학회지 2002;26(2):251-257 |
19 | 정세환, 배광학, 문혁수, 백대일, 김종배, 박덕영. 자몽종자추출물과 차추출물 및 UDCA를 배합한 구내분무액의 S. mutans와 구취 감소효과 및 치은염완화효과에 관한 연구. 대한구강보건학회지 1998;22(1):37-46 |
20 | Isokangas P, Alanen P, Tiesko J, Mainen KK. Xylitol chewing gum in caries prevention : a field study in children. JADA 1988;117:315-320 |
21 | Soderling E, Isokangas P, Mustakallio S, Makinen KK. Long-term xylitol consumption and Mutans Streptococci in plaque and saliva. Caries Res 1991;25:153-157 DOI ScienceOn |
22 | Sahni PS, Gillespie MJ, Botto RW, Otsuka AS. In vitro testing of xylitol as an anticariogenic agent. General Dentistry 2002;50(4):340-343 |
23 | Loesche WJ, Earnest R, Grossman NS, Corpron R. The effect of chewing xylitol gum on the plaque and saliva levels of Streptococcus mutans. JADA 1984;108:587-592 |
24 | Borradaile NM, de Dreu LE, Barrett PH, Huff MW. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. J Lipid Res 2002;43:1544-1554 DOI ScienceOn |
25 | 최원균, 노용철, 황성연. 자몽종자추출물과 폴리리신혼합물의 식품부패균에 대한 항균효과. 한국식생활문화학회지 2000;5(1):9-15 과학기술학회마을 ScienceOn |
26 | Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and In Vitro toxicity. J Altern Complement Med 2002;8:333-340 DOI ScienceOn |
27 | Borradaile NM, de Dreu LE, Barrett PH, Behrsin CD, Huff MW. Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation. Biochemistry 2003;42:1283-1291 DOI ScienceOn |
28 | Simons D, Brailsford S, Kidd EAM, Beighton D. The effect of chlorhexidine acetate/xylitol chewing gum on the plaque and gingival indices of elderly occupants in residential homes: A 1-year clinical trial. J Clin Periodontol 2001;28:1010-1015 DOI ScienceOn |