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http://dx.doi.org/10.14368/jdras.2014.30.1.28

Review of osteochondroma: involved in temporomandibular joint  

Lee, Gi-Ho (Department of Advanced General Dentistry, Dankook University Dental Hospital)
Song, Young-Gyun (Department of Advanced General Dentistry, Dankook University Dental Hospital)
Publication Information
Journal of Dental Rehabilitation and Applied Science / v.30, no.1, 2014 , pp. 28-35 More about this Journal
Abstract
Osteochondroma is the most common benign bone tumor. The majority of osteochondromas (85%) present as solitary, nonhereditary lesions. In general, osteochondroma has no symptoms,however, facial asymmetry, malocclusion, crossbite and mouth opening can be occurred in case of temporomandibular joint involved. Radiologic analyses are indispensable element to diagnose osteochondroma and pathogenetic analysis showed that hereditary multiple osteochondromas are caused by mutations in either of two genes: exostosis(multiple)-1 (EXT1), which is located on chromosome 8q24.11 - q24.13 or exostosis(multiple)-2 (EXT2), which is located on chromosome 11p11 - 12. Recently, reduced mRNA of EXT1 was described in nonhereditary osteochondromas. The treatment of choice for osteochondroma is surgical unless the skeleton is still immature. Surgery associated with orthodontic treatment can be a valid approach to minimize facial asymmetry and malocclusion in case of temporomandibular with osteochondroma.
Keywords
osteochondroma; temporomandibular joint;
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