Browse > Article
http://dx.doi.org/10.14368/jdras.2013.29.2.141

A Literature Review on Nano-Modified Implant Surfaces  

Park, Go-Woon (Department of Prosthodontics and Research Institute of Oral Science, Gangneung-Wonju National University)
Cha, Min-Sang (Department of Dentistry, Gangneung Asan Hospital, University of Ulsan, College of Medicine)
Kim, Dae-Gon (Department of Prosthodontics and Research Institute of Oral Science, Gangneung-Wonju National University)
Park, Chan-Jin (Department of Prosthodontics and Research Institute of Oral Science, Gangneung-Wonju National University)
Cho, Lee-Ra (Department of Prosthodontics and Research Institute of Oral Science, Gangneung-Wonju National University)
Publication Information
Journal of Dental Rehabilitation and Applied Science / v.29, no.2, 2013 , pp. 141-151 More about this Journal
Abstract
The nano-surface modification techniques could be classified; internal modifications which enhance surface roughness and porosity in nano level and external modifications as nano particle coating. Nano-modified implant surface has various morphograpies such as nanotube, nanopit, nanonodule and polymorphic structures. Creating surface depends upon preparation method and material, however, there is no standard preparation technique not yet. The nano-modified surfacet is electrochemically stable comparing with the surface modified in micron level. Nano-modified surface has little cytotoxicity, stimulates osteoblast proliferation and differentiation. Moreover, it decreases soft tissue intervention by interrupting the proliferation of fibroblast. Nanostructure has similar size and shape with cells and proteins, consequently leads to good biocompatibility and enhanced osseointegration. However, the actual effect in vivo is limited, due to the distance of effect. Even if nano-modified surface has antibiotic property due to photocatalysis, short duration time makes clinical application questionable. Further investigations should focus on the optimal nano-modified surface, which has many potentials.
Keywords
nano-modified surface; cell response; photocatalysis; osstointegration;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Song HJ. Advanced surface modification techniques for enhancing osseointegration of titanium implant. Journal of Korean dental association. 2010;48(2): 96-105.
2 Gittens RA, McLachlan T, Olivares-Navarrete R, Cai Y, Berner S, Tannenbaum R, Schwartz Z, Sandhage KH, Boyan BD. The effects of combined micron-/ submicron-scale surface roughness and nanoscale features on cell proliferation and differentication. Biomaterials. 2011;32(13):3395-403.   DOI   ScienceOn
3 Kim SJ, Park JM, Bae TS, Park EJ. Precalcification treatment of TiO2 nanotube on Ti-6Al-4V alloy. J Korean Acad Prosthodont. 2009;47:39-45   DOI   ScienceOn
4 Kim HS, Yang Y, Koh JT, Lee KK, Lee DJ, Lee KM, Park SW. Fabrication and characterization of functionally graded nano-micro porous titanium surface by anodizing. J Biomed Mater Res B Appl Biomater. 2009;88(2):427-35.
5 Cui CX, Gao X, Qi YM, Liu SJ, Sun JB. Microstructure and antibacterial property of in situ TiO2 nanotube layers/titanium biocomposites. J Mech Behav Biomed Mater. 2012;8:178-83.   DOI   ScienceOn
6 Demetrescu I, Pirvu C, Mitran V. Effect of nanotopographical features of Ti/TiO2 electrode surface on cell response and electrochemical stability in artificial saliva Bioelectrochemistry. 2010;79(1):122-9   DOI   ScienceOn
7 Huang HH, Chen JY, Lin MC, Wang YT, Lee TL, Chen LK. Blood responses to titanium surface with TiO2 nano-mesh structure. Clin Oral Implants Res. 2012;23(3):379-83.   DOI   ScienceOn
8 Bueno Rde B, Adachi P, Castro-Raucci LM, Rosa AL, Nanci A, Oliveira PT. Oxidative nanopatterning of titanium surfaces promotes production and extracellular accumulation of osteopontin. Braz Dent J. 2011;22(3):179-84.   DOI
9 Hori N, Iwasa F, Ueno T, Takeuchi K, Tsukimura N, Yamada M, Hattori M, Yamamoto A, Ogawa T. Selective cell affinity of biomimetic micro-nanohybrid structured TiO2 overcomes the biological dilemma of osteoblasts. Dent Mater. 2010;26(4): 275-87.   DOI   ScienceOn
10 Ueno T, Tsukimura N, Yamada M, Ogawa T. Enhanced bone-integration capability of alkali- and heat-treated nanopolymorphic titanium in micro-tonanoscale hierarchy Biomaterials. 2011;32(30):7297-308.   DOI   ScienceOn
11 Kloss FR, Steinmüller-Nethl D, Stigler RG, Ennemoser T, Rasse M, Hächl O. In vivo investigation on connective tissue healing to polished surfaces with different surface wettability. Clin Oral Implants Res. 2011;22(7):699-705.   DOI   ScienceOn
12 Mozumder MS, Zhu J, Perinpanayagam H. Titaniapolymeric powder coatings with nano-topography support enhanced human mesenchymal cell responses. J Biomed Mater Res A. 2012;100(10): 2695-709.
13 Huang J, Li X, Koller GP, Di Silvio L, Vargas-Reus MA, Allaker RP. Electrohydrodynamic deposition of nanotitanium doped hydroxyapatite coating for medical and dental applications. J Mater Sci Mater Med. 2011;22(3):491-6.   DOI
14 Fröjd V, Linderbäck P, Wennerberg A, Chávez de Paz L, Svensäter G, Davies JR. Effect of nanoporous TiO2 coating and anodized Ca2+ modification of titanium surfaces on early microbial biofilm formation. BMC oral health. 2011;8:11-8
15 Meirelles L, Albrektsson T, Kjellin P, Arvidsson A, Franke-Stenport V, Andersson M, Currie F, Wennerberg A. Bone reaction to nano hydroxyapatite modified titanium implants placed in a gap-healing model. J Biomed Mater Res A. 2008;87(3):624-31.
16 Cheng Z, Guo C, Dong W, He FM, Zhao SF, Yang GL. Effect of thin nano-hydroxyapatite coating on implant osseointegration in ovariectomized rats. J Mech Behav Biomed Mater. 2012;8:178-83.   DOI   ScienceOn
17 Park J, Bauer S, Schlegel KA, Neukam FW, von der Mark K, Schmuki P. TiO2 nanotube surfaces: 15 nman optimal length scale of surface topography for cell adhesion and differentiation. Small 2009;5:666-671.   DOI   ScienceOn
18 Brammer KS, Oh S, Cobb CJ, Bjursten LM, van der Heyde H, Jin S. Improved bone-forming functionality on diameter-controlled TiO2 nanotube surface. Acta Biomaterialia. 2009;5:3215-3223   DOI   ScienceOn
19 Dalby MJ, Gadegaard N, Tare R, Andar A, Riehle MO, Herzyk P, Wilkinson CD, Oreffo RO. The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater. 2007;6(12):997-1003.   DOI   ScienceOn
20 Li Y, Gao Y, Shao B, Xiao J, Hu K, Kong L. Effects of hydrofluoric acid and anodized micro and micro/nano surface implants on early osseointegration in rats. Br J Oral Maxillofac Surg. 2012;50(8): 779-83.   DOI   ScienceOn
21 Kim WH, Kim KN. An overview of research trends in antibacterial coatings on titanium implants. Journal of Korean dental association. 2010;48(2):113-118.
22 Suketa N, Sawase T, Kitaura H, Naito M, Baba K, Nakayama K, Wennerberg A, Atsuta M. An Antibacterial Surface on Dental Implants, Based on the Photocatalytic Bactericidal Effect. Clin Implant Dent Relat Res. 2005;7(2):105-11.   DOI   ScienceOn
23 Oh SH. Nanotechnology in the surface treatment of titanium implant. Journal of Korean dental association. 2010;48(2):106-112.