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The Change of Facial Contouring after Unilateral Injection of Botulinum Toxin in Unilateral Masseter Hypertrophy Patients  

Cha, Yu-Rim (Department of Oral medicine, college of dentistry, Yonsei University)
Kim, Young-Gun (Department of Oral medicine, college of dentistry, Yonsei University)
Kim, Ji-Hyun (Department of Oral medicine, college of dentistry, Yonsei University)
Shim, Young-Joo (Department of Oral medicine, college of dentistry, Yonsei University)
Kim, Seong-Taek (Department of Oral medicine, college of dentistry, Yonsei University)
Publication Information
Journal of Dental Rehabilitation and Applied Science / v.27, no.2, 2011 , pp. 247-251 More about this Journal
Abstract
Botulinum toxin type A (BoNT-A) is used for treating bilateral masseter hypertrophy since 1994. Recently there have been more clinical studies in this area, with some authors reporting that BoNT-A can reduce the size of the masseter muscle, as documented by photography, ultrasonography, computed tomography, and 3D(three dimensional) laser scan. However, earlier studies were only for bilateral masseter hypertrophy cases, not for unilateral masseter hypertrophy cases. The aim of this study was to use 3D laser scanning to evaluate changes in the external facial contour induced by unilateral BoNT-A injection. BoNT-A was injected into hypertrophic masseter muscle unilaterally in 10 patients with asymmetric masseter hypertrophy. The clinical effects of unilaterally injected BoNT-A were evaluated before the injection and 4, 8, and 12weeks after the injection using 3D laser scan. And the mean values of both sides (injection and non-injection sides) were compared with. At injection side, mean values of the volume and the bulkiest height at each time point diminished significantly between pre-injection and 4, 8, and 12weeks post-injection. At non-injection side, in contrast, mean values of the volume and the bulkiest height diminished also but less than that of injected side, and there was no statistical significance. In this limited study, we concluded that the unilaterally BoNT-A injection side showed greater mean values of the reduction of muscle volume than non-injection side at 4, 8, and 12 weeks after the injection.
Keywords
botulinum toxin; unilateral masseter hypertrophy;
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1 Lance L. Simpson. Botulinum Toxin: A Deadly Poison Sheds Its Negative Image Ann Intern Med. 1996;125:616-617   DOI   ScienceOn
2 Louis Mandel and Marsha Tharakan. Treatment of Unilateral Masseteric Hypertrophy With Botulinum Toxin: Case Report J Oral Maxillofac Surg 1999;57:1017-1019   DOI   ScienceOn
3 W. H. Jost. Other indication of boturinum toxin therapy European Journal of Neurology 2006, 13(Suppl. 1): 65-69   DOI
4 Seung Jin Lee, William D. McCall, Jr.,Young Ku Kim et al. Effect of Boturinum Toxin Injection on Nocturnal Bruxism Am. J. Phys. Med. Rehabil. Vol. 89, No. 1, January 2010
5 Marvin Schwarts, Brian Freude. Treatment of Temporomandibular Disorders with Boturinum Toxin The Clinical Juornal of Pain 2002;18: S198-S203   DOI
6 Seong Taek Kim, Chong Youl Kim. Use of The ID Migrane Questionnaire for Migrane in TMJ and Orofacial Pain Clinic Headache 2006;46:253-258   DOI   ScienceOn
7 Wagner Henriques Castro, Rodrigo Santiago Gomez, Jacqueline da Silva Oliveira, et al.. Boturinum Toxin Type A in the Management of Masseter Muscle Hypertrophy American Association of Oral and Maxillofacial Surgeons 2005;63:20-24
8 Jens J. von Lindern, Bernd Niederhagen, Thorsten Appel, et al.. Type A Boturinum Toxin for the Treatment of Hypertrophy of the Masseter and Temporal Muscles: An Alternative Treatment Plastic And Reconstructive Surgery 2001;107: 327-332   DOI   ScienceOn
9 E. W. H. To, A. T. Ahuja, W. S. Ho, et al. A prospective study of the effect of boturinum toxin A on Masseteric muscle hypertrophy with ultrasonographic and electromyographic measurement British Journal of Plastic Surgery 2001;54;197-200   DOI   ScienceOn
10 Ki Seo Kim, Young Sub Byun, Yong Jeong Kim, et al. Muscle Weakness After Repeated Injection of Botulinum Toxin Type A Evaluated According to Bite Force Measurement of Human Masseter Muscle Dermatol Surg 2009;35:1-6   DOI   ScienceOn
11 Seong Wook Choe, Wan Ik Cho, Chang Gyun Lee, et al. Effects of Boturinum Toxin Type A on Contouring of the Lower Face Dermatol Surg 2005;31:502-508   DOI
12 S. Bertram, A. Rudisch, G. Bodner, et al. The short-term effect of stabilization-type splints on the local asymmetry of masseter muscle sites Journal of Rehabilitation 2001;28:1139-1143   DOI   ScienceOn
13 Woo Hyun Shim, Seong Taek Kim. Effect of Botulinum Toxin Type A Injection on Lower Facial Contouring Evaluated by Three-dimensional Laser Scan   DOI