Browse > Article
http://dx.doi.org/10.5851/kosfa.2016.36.2.237

Anti-Aging Effects of the Hanwoo Leg Bone, Foot and Tail Infusions (HLI, HFI and HTI) on Skin Fibroblast  

Seol, Ja young (Division of Biological Science, Sookmyung Women's University)
Yoon, Ji Young (Department of Le Cordon Blue Hospitality Management, Sookmyung Women's University)
Jeong, Hee Sun (Traditional Dietary Life Food, Graduate School of Traditional Culture and Arts, Sookmyung Women's University)
Joo, Nami (Department of Food & Nutrition, Sookmyung Women's University)
Choi, Soon Young (Division of Biological Science, Sookmyung Women's University)
Publication Information
Food Science of Animal Resources / v.36, no.2, 2016 , pp. 237-243 More about this Journal
Abstract
Many researchers revealed that collagen contribute to maintaining the skin’s elasticity and inhibit wrinkling of skin. Korean native cattle (Hanwoo) bone (leg bone, foot and tail) infusion contains the various inorganic materials, collagen and chondroitin sulfate. All of this, a large quantity of collagen is included in Hanwoo infusion. Therefore, this study emphasized on the effects of collagen in the Hanwoo bone infusion. For the first time, Hanwoo bone infusions were directly added to the media of Human Dermal Fibroblast (NHDF-c) to test anti-aging effects. First, it was identified that growth rate of skin fibroblast was increased. Furthermore, the Hanwoo bone infusion increased a 50% of fibroblast collagen synthesis. Also, suppression of skin fibroblast aging was confirmed by treatment Hanwoo bone infusion. In conclusion, this study demonstrates the effects of infusion made from Hanwoo leg bone, foot and tail on anti-aging, wrinkle inhibiting and skin fibroblast elasticity maintaining. Therefore, this study identified that traditional infusion has effects that are good for skin elasticity.
Keywords
Korean native cattle (Hanwoo); leg bone infusion; foot infusion; tail infusion; skin fibroblast (NHDF-c); anti-aging;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Imokawa, G. (2008) Recent advances in characterizing biological mechanisms underlying UV-induced wrinkles: A pivotal role of fibrobrast-derived elastase. Arch. Dermatol. Res. 300, 7-20.   DOI
2 Ichikawa, S., Morifuji, M., Ohara, H., Matsumoto, H., Takeuchi, Y., and Sato, K. (2010) Hydroxyproline-containing dipeptides and tripeptides quantified at high concentration in human blood after oral administration of gelatin hydrolysate. Int. J. Food Sci. Nutr. 61, 52-60.   DOI
3 Joseph, S., Allen, R. G., Samuel, B., Arthur, B., and Vincent, J. C. (2000) Is β-galactosidase staining a marker of senescence in vitro and in vivo? Exp. Cell Res. 257, 162-171.   DOI
4 Kim, E. J., Kim, M. K., Jin, X. J., Oh, J. H., Kim, J. E., and Chung, J. H. (2010) Skin aging and photoaging alter fatty acids composition, including 11,14,17-eicosatrienoic acid, in the epidermis of human skin. J. Korean Med. Sci. 25, 980-983.   DOI
5 Kim, K. S. (2003) Review of health functional ingredient in food. Pusan Women's Univ. J. 25, 79-94.
6 Koji, I., Takanori, H., Yasuki, T., Fumiki, M., Kenji, S., Yasushi, N., Akane, H., Yasuhiro, K., Yukihiro, N., and Kozo, O. (2005) Identification of food-derived collagen peptides in human blood after oral ingestion of gelation hydrolysates. J. Agric. Food Chem. 53, 6531-6536.   DOI
7 Park, D. Y. and Lee, Y. S. (1982) An experiment in extracting efficient nutrients from sagol bone stock. J. Korean Nutr. Food 11, 47-52.
8 Makrantonaki, E. and Zouboulis, C. C. (2007) Molecular mechanisms of skin aging state of the art. Ann. N Y Acad. Sci. 1119, 40-50.   DOI
9 Matsuda, N., Koyama, Y. I., Hosaka, Y., Ueda, H., Watanabe, T., Araya, T., Irie, S., and Takehana, K. (2006) Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in the dermis. J. Nutr. Sci. Vitaminol. 52, 211-215.   DOI
10 Park, D. Y. (1986) Total nitrogen and free amino acid contents in shank bone stock according to boiling time. J. Korean Soc. Food Nutr. 15, 243-248.
11 Ronald, K. G. and Susan, M. K. (2005) Quantitative assay of senescence-associated-galactosidase activity in mammalian cell extracts. Analyt. Biochem. 343, 329-334.   DOI
12 Saito, M. and Marumo, K. (2010) Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos Int. 21, 195-214.   DOI
13 Salasznyk, R. M., Williams, W. A., Boskey, A., Batorsky, A., and plopper, G. E. (2004) Adhesion to vitronectin and collagen I promotes osteogenic differentiation of human mesenchymal stem cells. J. Biomed. Biotechnol. 1, 24-34.
14 Schwartz, S. R. and Park, J. S. (2012) Ingestion of BioCell Collagen®, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs. Clin. Interv. Aging 7, 267-273.
15 Seol, M. Y. and Jang, M. S. (1990) A study on mineral contents in sagol bone stock. Korean J. Food Cookery Sci. 6, 21-26.
16 Vivian, Z., Vanessa, F., Marina, C. R., Geórgia Álvares, C., Ruy, G. J., and Gláucia, M. M. S. (2011) Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity. J. Medicinal Food 14, 618-624.   DOI
17 Yasutaka, S., Koji, I., Fumiki, M., Takaaki, I., Toshio, M., Chikako, O., Toshio, T., Park, E. Y., Nakamura, Y., and Sato, K. (2009) Effect of prolyl-hydroxyproline (Pro-Hyp), a food-derived collagen peptide in human blood, on growth of fibroblast from mouse skin. J. Agric. Chem. 57, 444-449.   DOI
18 Shizuka, Y., Yoshizawa, Y., Kawakubo, A., Ikeda, T., Yanagiguchi, K., and Hayashi, Y. (2013) Early gene and protein expression associated with osteoblast differentiation in response to fish collagen peptides powder. Dental Mater. J. 32, 233-240.   DOI
19 Sugihara, F., Inoue, N., Kuwamori, M., and Taniguchi, M. (2012) Quantification of hydroxyprolyl-glycine(Hyp-Gly) in human blood after ingestion of collagen hydrolysate. J. Biosci. Bioeng. 113, 202-203.   DOI
20 Talwar, J. S., Griffiths, C. E. M., Fisher, G. J., Hamilton, T. A., and Vorhees, J. J. (1995) Reduced type I and type III pro-collagens in photodamaged adult human skin. J. Invest. Dermatol. 105, 285-290.   DOI
21 Yoon, J. Y., Choi, S. Y., Jeong, H. S., Park, Y. I., Kim, D. S., and Joo, N. M. (2015) A comparative study on quality and physicochemical characteristics of segmental bone Korean beef infusion. Korean J. Food Nutr. 28, 470-477.   DOI
22 Zague, V. (2008) A new view concerning the effects of collagen hydrolysate intake on skin properties. Arch. Dermatol. Res. 300, 479-483.   DOI