Calcium Mobilization Inhibits Lipid Accumulation During the Late Adipogenesis via Suppression of PPARγ and LXRα Signalings |
Kim, Seung-Jin
(Dept. of Biological sciences, College of Natural sciences, Chonnam National University)
Choi, Ho-Jung (Dept. of Biological sciences, College of Natural sciences, Chonnam National University) Jung, Chung-Hwan (Dept. of Biological sciences, College of Natural sciences, Chonnam National University) Park, Sung-Soo (Dept. of Biological sciences, College of Natural sciences, Chonnam National University) Cho, Seung-Rye (Dept. of Biological sciences, College of Natural sciences, Chonnam National University) Oh, Se-Jong (Division of Animal Science, College of Agriculture and Life Science, Chonnam National University) Kim, Eung-Seok (Dept. of Biological sciences, College of Natural sciences, Chonnam National University) |
1 | Chen, G., Liang, G., Ou, J., Goldstein, J. L., and Brown, M. S. (2004) Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc. Natl. Acad Sci. USA 101, 11245-11250. DOI ScienceOn |
2 | Campbell, A. K. (1983) Intracellular calcium: Its universal role as regulator. John Wiley & Sons, Inc. Chichester; New York. |
3 | Shi, H., Halvorsen, Y. D., Ellis, P. N., Wilkison, W. O., and Zemel, M. B. (2000) Role of intracellular calcium in human adipocyte differentiation. Physiol Genomics. 3, 75-82. |
4 | Forman, B. M., Tontonoz, P., Chen, J., Brun, R. P., Spiegelman, B. M., and Evans, R. M. (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83, 803-812. DOI ScienceOn |
5 | Volle, D. H., Mouzat, K., Duggavathi, R., Siddeek, B., Dechelotte, P., Sion, B., Veyssiere, G., Benahmed, M., and Lobaccaro, J. M. (2007) Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility. Mol. Endocrinol. 21, 1014-1027. DOI ScienceOn |
6 | Fu, M., Sun, T., Bookout, A. L., Downes, M., Yu, R. T., Evans, R. M., and Mangelsdorf, D. J. (2005) A Nuclear Receptor Atlas: 3T3-L1 adipogenesis. Mol. Endocrinol. 19, 2437-2450. DOI ScienceOn |
7 | Guilherme, A., Virbasius, J. V., Puri, V., and Czech, M. P. (2008) Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat. Rev. Mol. Cell Biol. 9, 367-377. DOI ScienceOn |
8 | Kim, H. B., Kong, M., Kim, T. M., Suh, Y. H., Kim, W. H., Lim, J. H., Song, J. H., and Jung, M. H. (2006) NFATc4 and ATF3 negatively regulate adiponectin gene expression in 3T3-L1 adipocytes. Diabetes. 55, 1342-1352. DOI ScienceOn |
9 | Laffitte, B. A., Joseph, S. B., Walczak, R., Pei, L., Wilpitz, D. C., Collins, J. L., and Tontonoz, P. (2001) Autoregulation of the human liver X receptor alpha promoter. Mol. Cell. Biol. 21, 7558-7568. DOI ScienceOn |
10 | Draznin, B., Sussman, K. E., Eckel, R. H., Kao, M., Yost, T., and Sherman, N. A. (1988) Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia. J. Clin. Invest. 82, 1848-1852. DOI |
11 | Peet, D. J., Turley, S. D., Ma,W., Janowski, B. A., Lobaccaro, J. M., Hammer, R. E., and Mangelsdorf, D. J. (1998) Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR. Cell. 93, 693-704. DOI ScienceOn |
12 | Pilvi, T.K., Storvik, M., Louhelainen, M., Merasto, S., Korpela, R., and Mervaala, E. M. (2008) Effect of dietary calcium and dairy proteins on the adipose tissue gene expression profile in diet-induced obesity. J Nutrigenet Nutrigenomics. 1, 240-251. DOI ScienceOn |
13 | Rosen, E. D. and Spiegelman, B. M. (2006) Adipocytes as regulators of energy balance and glucose homeostasis. Nature. 444, 847-853. DOI ScienceOn |
14 | Liang, G., Yang, J., Horton, J. D., Hammer, R. E., Goldstein, J. L., and Brown, M. S. (2002) Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J. Biol. Chem. 277, 9520-9528. DOI ScienceOn |
15 | Sekiya, M., Yahagi, N., Matsuzaka, T., Takeuchi, Y., Nakagawa, Y., Takahashi, H., Okazaki, H., Iizuka, Y., Ohashi, K., Gotoda, T., Ishibashi, S., Nagai, R., Yamazaki, T., Kadowaki, T., Yamada, N., Osuga, J., and Shimano, H. (2007) SREBP-1-independent regulation of lipogenic gene expression in adipocytes. J. Lipid. Res. 48, 1581-1591. DOI ScienceOn |
16 | Shi, Y. and Burn, P. (2004) Lipid metabolic enzymes: emerging drug targets for the treatment of obesity. Nat. Rev. Drug Discov. 3, 695-710. DOI ScienceOn |
17 | Szabo, E., Qiu, Y., Baksh, S., Michalak, M., and Opas, M. (2008) Calreticulin inhibits commitment to adipocyte differentiation. J. Cell Biol. 182, 103-116. DOI ScienceOn |
18 | Rosen, E. D., Walkey, C. J., Puigserver, P., and Spiegelman, B. M. (2000) Transcriptional regulation of adipogenesis. Genes. Dev. 14, 1293-1307. |
19 | Schmid, B., Rippmann, J. F., Tadayyon, M., and Hamilton, B. S. (2005) Inhibition of fatty acid synthase prevents preadipocyte differentiation. Biochem. Biophys. Res. Commun. 328, 1073-1082. DOI ScienceOn |
20 | Moniotte, S., Kobzik, L., Feron, O., Trochu, J. N., Gauthier, C., and Balligand, J. L. (2001) Upregulation of beta(3)- adrenoceptors and altered contractile response to inotropic amines in human failing myocardium. Circulation. 103, 1649-1655. DOI ScienceOn |
21 | Papakonstantinou, E., Flatt, W. P., Huth, P. J., and Harris, R. B. (2003) High dietary calcium reduces body fat content, digestibility of fat, and serum vitamin D in rats. Obes. Res. 11, 387-394. DOI ScienceOn |
22 | Kitamura, N., Wong, P., and Matsumura, F. (2006) Mechanistic investigation on the cause for reduced toxicity of TCDD in wa-1 homozygous TGFalpha mutant strain of mice as compared its matching wild-type counterpart, C57BL/6J mice. J. Biochem. Mol. Toxicol. 20, 151-158. DOI ScienceOn |
23 | Juvet, L. K., Andresen, S. M., Schuster, G. U., Dalen, K. T., Tobin, K. A., Hollung, K., Haugen, F., Jacinto, S., Ulven, S. M., Bamberg, K., Gustafsson, J. A., and Nebb, H. I. (2003) On the role of liver X receptors in lipid accumulation in adipocytes. Mol. Endocrinol. 17, 172-182. DOI ScienceOn |
24 | Kershaw, E. E. and Flier, J. S. (2004) Adipose tissue as an endocrine organ. J. Clin. Endocrinol. Metab. 89, 2548-2556 DOI ScienceOn |
25 | Kim, E., Xie, S., Yeh, S. D., Lee, Y. F., Collins, L. L., Hu, Y. C., Shyr, C. R., Mu, X. M., Liu, N. C., Chen, Y. T., Wang, P. H., and Chang, C. (2003) Disruption of TR4 orphan nuclear receptor reduces the expression of liver apolipoprotein E/CI/C-II gene cluster. J. Biol. Chem. 278, 46919-46926. DOI ScienceOn |
26 | Duffus, J. H. and Patterson, L. J. (1974) Control of cell division in yeast using the ionophore, A23187 with calcium and magnesium. Nature 251, 626-627. DOI ScienceOn |
27 | Lane, M. D., Tang, Q. Q., and Jiang, M. S. (1999) Role of the CCAAT enhancer binding proteins (C/EBPs) in adipocyte differentiation. Biochem. Biophys. Res. Commun. 266, 677-683. DOI ScienceOn |
28 | Gregor, M. F. and Hotamisligil, G. S. (2007) Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J. Lipid. Res. 48, 1905-1914. DOI ScienceOn |
29 | Jensen, B., Farach-Carson, M. C., Kenaley, E., and Akanbi, K. A. (2004) High extracellular calcium attenuates adipogenesis in 3T3-L1 preadipocytes. Exp. Cell Res. 301, 280-292. DOI ScienceOn |
30 | Joseph, S. B., Laffitte, B. A., Patel, P. H., Watson, M. A., Matsukuma, K. E., Walczak, R., Collins, J. L., Osborne, T. F., and Tontonoz, P. (2002) Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J. Biol. Chem. 277, 11019-11025. DOI ScienceOn |
31 | Evans, R. M. (1988) The steroid and thyroid hormone receptor superfamily. Science 240, 889-895. DOI |
32 | Chawla, A., Schwarz, E. J., Dimaculangan, D. D., and Lazar, M. A. (1994) Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135, 798-800. DOI ScienceOn |
33 | Giguere, V. (1999) Orphan nuclear receptors: from gene to function. Endocr. Rev. 20, 689-725. DOI ScienceOn |
34 | Gregoire, F. M., Smas, C. M., and Sul, H. S. (1998) Understanding adipocyte differentiation. Physiol. Rev. 78, 783-809 |
35 | Cariou, B., van Harmelen, K., Duran-Sandoval, D., van Dijk, T. H., Grefhorst, A., Abdelkarim, M., Caron, S., Torpier, G., Fruchart, J. C., Gonzalez, F. J., Kuipers, F., and Staels, B. (2006) The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice. J. Biol. Chem. 281, 11039-11049. DOI ScienceOn |
36 | Zayzafoon, M. (2006) Calcium/calmodulin signaling controls osteoblast growth and differentiation. J. Cell Biochem. 97, 56-70. DOI ScienceOn |
37 | Darlington, G. J., Ross, S. E., and MacDougald, O. A. (1998) The role of C/EBP genes in adipocyte differentiation. J. Biol. Chem. 273, 30057-30060. DOI |
38 | Berger, J., Tanen, M., Elbrecht, A., Hermanowski-Vosatka, A., Moller, D. E., Wright, S. D., and Thieringer, R. (2001) Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta-hydroxysteroid dehydrogenase type 1 expression and activity. J. Biol. Chem. 276, 12629-12635. DOI ScienceOn |
39 | Berridge, M. J. (1993) Inositol trisphosphate and calcium signalling. Nature 361, 315-325. DOI ScienceOn |
40 | Whitehead, J. P., Molero, J. C., Clark, S., Martin, S., Meneilly, G., and James, D. E. (2001) The role of Ca2+ in insulin-stimulated glucose transport in 3T3-L1 cells. J. Biol. Chem. 276, 27816-27824. DOI ScienceOn |