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http://dx.doi.org/10.5851/kosfa.2010.30.4.545

Effects of Casein Hydrolysate on the Systolic Blood Pressure and Serum Lipid Profiles in Spontaneously Hypertensive Rats  

Do, Jeong-Ryong (Korea Food Research Institute)
Back, Su-Yeon (Korea Food Research Institute)
Lim, Sang-Dong (Korea Food Research Institute)
Kim, Hyun-Ku (Korea Food Research Institute)
Sung, Ki-Seung (Korea Food Research Institute)
Han, Chan-Kyu (Korea Food Research Institute)
Publication Information
Food Science of Animal Resources / v.30, no.4, 2010 , pp. 545-550 More about this Journal
Abstract
The effects of casein hydrolysate on blood pressure (BP) and serum lipid profiles were investigated in spontaneously hypertensive rats (SHR). Twenty-four 6-wk old male SHRs were assigned to 3 groups in a completely randomized design. Experimental groups were as follow: control, market milk group (MLG) and casein hydrolysate group (CHG). Reference blood pressure (RBP) showed average $198.94{\pm}1.46mmHg$. Blood pressure (BP) of CHG reduced 24 mmHg after 2 wk of treatment, but these increased after 3 wk. BP of CHG was significantly lower than BP of Control in experimental time (p<0.05). Serum lipid profiles were not differ significantly among groups (p<0.05). These data suggest that casein hydrolysate may beneficially improvement of blood pressure level in SHR.
Keywords
casein hydrolysate; blood pressure; serum lipid; spontaneously hypertensive rat;
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