Browse > Article

Cholesterol Removal of Milk and Dairy Products using ${\beta}-Cyclodextrin$  

Han, Eun-Mi (Department of Food Science and Technology, Sejong University)
Kim, Song-Hee (Department of Food Science and Technology, Sejong University)
Kwak, Hae-Soo (Department of Food Science and Technology, Sejong University)
Publication Information
Food Science of Animal Resources / v.26, no.4, 2006 , pp. 540-547 More about this Journal
Abstract
This review highlights areas of interest in the cholesterol removal of milk and dairy products. The demand for cholesterol removal has increased due to consumer demand for cholesterol-reduced products. At present the best method for producing without changing flavor, taste and texture of the products is entrapping cholesterol by ${\beta}-cyclodextrin({\beta}-CD)$. Especially, crosslinking of ${\beta}-CD$ is important due to recycling that could be separated the ${\beta}-CD$ from treated cream or milk. The recycling can be up to 10 times with keeping the rate of cholesterol removal. Various functional milk and dairy products can be produced in this manner. This report reviews general information including methods of cholesterol removal, crosslinking of ${\beta}-CD$, and recycling of the ${\beta}-CD$ in milk and dairy products.
Keywords
cholesterol removal; ${\beta}-cyclodextrin$; recycling; crosslinking;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Han, E. M., Kim, S. H., Ahn, J., and Kwak, H. S. (2005) Cholesteol removal from homogenized milk with crosslinked ${\beta}-cyclodextrin$ by adipic acid. Asian-Aust. J. Anim. Sci. 18, 1794-1799   DOI
2 Hedges, A., Shieh W., and Ameral, R. (1993) Process for removal of residue of cyclodextrin. Austrailia Patent WO 93/24022
3 Hwang, J. H., Lee, S. J., and Kwak, H. S. (2005) Change of properties and cholesterol lowering effect in evening primrose oil-added and cholesterol-reduced milk. AsianAust. J. Anim. Sci. 18, 1041-1047
4 Jung, T. H., Park, H. S., and Kwak, H. S. (2005) Optimization of cholesterol removal by crosslinked ${\beta}$ -cyclodextrin in egg yolk. Food Sci. Biotechnol. 14, 793-797
5 Jung, T. H., Kim, J. J., Yu, S. H., Ahn, J., and Kwak, H. S. (2005) Properties of cholesterol-reduced butter and effect of gamma linolenic acid added butter on blood cholesterol. Asian-Aust. J. Anim. Sci. 18, 1646-1654   DOI
6 Kim, J. J., Jung, T. H., Ahn, J., and Kwak, H. S. (2006) Properties of cholesterol-reduced butter made with 13 -CD and added evening primrose oil and phytosterols. J. Dairy Sei. 89, 4503-4510   DOI   ScienceOn
7 Kosikowski, F. V. (1990) 'Cholesterol-Free' milk and milk products : limitations in production and labeling. Food Technol. 11
8 Kwak, H. S., Suh, H. M., Abn, J., and Kwon, H. J. (2001) Optimization of ${\beta}-cyclodextrin$ recycling process for cholesterol removal in cream. Asian-Aust. J. Anim. Sci. 14, 548-552   DOI
9 Shaw, P. E., Tatum, J. H., and Wilson, C. W. (1984) Improved flavor of navel orange and grapefruit juices by removal of bitter components with ${\beta}-cyclodextrin$ polymer. J. Agric. Food Chem. 32, 832-836   DOI
10 Kartha, K. P. R., and Srivastava, H. C. (1985) Reaction of epichlorohydrin with cabohydrate polymer II. Starch. 37, 297-301   DOI
11 Kim, S. H., Han, E. M., Ahn, J., and Kwak, H. S. (2005) Effect of crosslinked ${\beta}-cyclodextrin$ on quality of cholesterol-reduced cream cheese. Asian-Aust. J. Anim. Sci. 18, 584-589   DOI
12 Chang, E. J., Oh, H. I., and Kwak, H. S. (2001) Optimization of cholesterol removal conditions from homogenized milk by treatment with saponin. Asian-Aust. J. Animal Sci. 14, 844-849   DOI
13 Kwak, H. S., Kim, S. H., Kim, J. H., Choi, H. J., and Kang, J. (2004) Immobilized ${\beta}-cyclodextrin$ as a simple and recyclable method for cholesterol removal in milk. Arch. Pharm. Res. 27, 873-877   DOI   ScienceOn
14 Yen, G. and L, Tasi (1995) Cholesterol removal from a lard-water mixture with ${\beta}-cyclodextrin.$ J. Food Sci. 60, 561-564   DOI   ScienceOn
15 Kim, H. Y., Bea, H. Y., Kim, S. Y., and Kwak, H. S. (2006) Removal of cholesterol from Blue cheese by crosslinked ${\beta}-cyclodextrin.$ J. Dairy Sci. 89, Suppl . 1 . W34
16 Kwak, H. S., Chung, C. S., and Ahn, J. (2002) Flavor compounds of cholesterol-reduced Cheddar cheese slurries. Asian-Aust. J. Anim. Sci. 15, 117-123   DOI
17 Pagington, J. S. (1986) Beta-cyclodextrin. Perfumer & Flavorist
18 Sieber, R. (1993) Cholesterol removal from animal food - can it be justified. Fed. Dairy Res. Inst. 45, 1243-1247
19 Kim, H. S. and Lee, Y. E. (1996) Influence of crosslinking on gelatinization behavior and morphological change of potato starch. Kor. J. Food Sci. Technol. 28, 580-586   과학기술학회마을
20 Mentink, L., Serpelloni, M., Roquette, F. (1990) Process of refining mixture obtained from treatments of fatty media with cyclodextrin and containing complexes of cyclodextrin mainly with lipophilic substances other than fatty acids. Canadian Patent 90/01007
21 Kim, S. H., Kim, H. Y., and Kwak, H. S. (2006) Cholesterol removal from lard with crosslinked ${\beta}-cyclodextrin$. Asian-Aust. J. Anim. Sci. (submitted)
22 Wurzburg, O. B. (1986) Cross-linked starches. Modified starches. 6, 41-53
23 Takahashi, K, Hattori, K, and Toda, F. (1984) Monotosylated and ${\beta}-cyclodextrin$ prepared in an alkaline aqueous solution. Tetrahedron Lett. 25, 3331-3334   DOI   ScienceOn
24 De Miguel, I., Rieumajou, Y., and Betbeder, D. (1999) New methods to determine the extent of reaction of epichlorohydrin with maltodextrius. Carbohydrate Research., 319, 17-23   DOI   ScienceOn
25 Han, E. M., Kim, S. H., Kim, K. W., and Kwak, H. S. (2006) Recycling efficiency of crosslinked ${\beta}-cyclodextrin$ in milk and cream. Asian-Aust. J. Anim. Sci. (submitted)
26 Lee, J. S., Ustunol, Z., and Smith, D. M. (1993) Cholesterol removal from cream ${\beta}-cyclodextrin$ and derivatives. J. Dairy Sci. Abs. 158
27 Woo, K S., Hong, J. Y., and Lim, S. T. (2001) Physical properties of reversibly swellable cross-linked wheat starch. Food Eng. Prog. 5, 25-28
28 Kobayash, S., Kainuma, K., and Suzuki, S. (1975) Cyclodextrin-production and utilization of cyclodextrin. J. Jpn. Soc. Starch Sci. 28, 132-141
29 Kwak, H. S., lung, C. S., Seok, J. S., and Abn, J. (2003) Cholesterol removal and flavor development in Cheddar cheese. Asian-Aust. J. Anim. Sci. 16, 409-416   DOI
30 Nobnyuki, N. M., Mishima, Y, and Hideyuki, S. (1995) Method for recovering cyclodextrin. U. S. Patent. 544 9771
31 Chin, P. Y. and Chein, S. S. (1990) Methods of recovering and separation water-soluble cyclodextrin form cyclodextrin formation liquid. U. S Patent 4970164
32 Sidhu, G. S., Oakenfull, D. G., and Rooney, M. L. (1993) Composition and method for reducing cholesterol concentration. Austrailia Pantent WO 93/05084
33 Bea, H. Y., Kim, H. Y., Jung, T. H., and Kwak, H. S. (2006) Effects of crosslinked ${\beta}-cyclodextrin$ treatment on cholesterol removal, and chemical and sensory propeties in Feta cheese. J. Dairy Sci. 89, Suppl.1.W34
34 Kwak, H. S., Nam, C. G., and Abn, J. (2001) Low cholesterol Mozzarella cheese obtained from homogenized and ${\beta}-cyclodextrin-treated$ milk. Asian-Aust. J. Anim. Sci. 14, 268-275   DOI
35 Shukla, A., Bhaskar, A. R., Rizvi, S. H., and Mulvaney, S. J. (1994) Physicochemical and rheological properties of butter made from supercritically milk fat. J. Dairy Sci. 77. 45-54   DOI   ScienceOn
36 Glodstein, J. L. and Brown, M. S. (1977) The low-density lipoprotein pathway and its relation to atherosclerosis. Annu. Rev. Biochem. 46, 897-930   DOI   ScienceOn
37 Levy, R. I. (1981) Cholesterol, lipoproteins, apoproteins, and heart disease : present statusand future prospects. Clin. Chem., 27, 653-662
38 Weu, S., Timothy, C. P., and Allan, H. C. (1995) Cyclodextrin refining process. U. S. Patent 5393880
39 Smith, D. M. and Bennink, J. L. (1995) Cholesterol reduction in liquid egg yolk using ${\beta}-cyclodextrin$ J. Food Sci. 60, 691-694   DOI   ScienceOn
40 Ahn, J. and Kwak, H. S. (1999) Optimizing cholesterol removal in cream using ${\beta}-cyclodextrin$ and response surface methodology. J. Food Sci. 64, 629-632   DOI   ScienceOn
41 Pyorala, K. (1987) Dietary cholesterol in relation to plasma cholesterol and coronary heart disease. Am. J. Chem. Nutr. 45, 1176-1184   DOI
42 Shim, S. Y., Ahn, J., and Kwak, H. S. (2003) Funcitional properties of cholesterol-removal whipping cream treated by ${\beta}-cyclodextrin.$ J. Dairy Sci. 86, 2767-2772   DOI   ScienceOn
43 Kim, J. J., Yoo, S. H., Ahn, J., Jeon, W. M., and Kwak. H. S. (2005) The effect of evening primrose oil on chemical properties and lowering blood cholesterol in nutraceutical Cheddar cheese. Arch. Pharm. Res. 19, 450-458   DOI
44 Kim, S. H., Ahn, J., and Kwak, H. S. (2004) Cross linking of ${\beta}-cyclodextrin$ on cholesterol removal from milk. Arch. Pharm. Res. 27,1183-1187   DOI   ScienceOn
45 Lee, D. K., Abn, J., and Kwak, H. S. (1999) Cholesterol removal from homogenized milk with ${\beta}-cyclodextrin.$ J. Dairy Sci. 82, 2327-2330   DOI   ScienceOn
46 Pagington, J. S. (1987) ${\beta}-cyclodextrin$(the success of molecular inclusion). J. Br. Chem. 452
47 Biss, K., Ho, K. J., Mikkeisn., B. B., Lowis., L., and Tayor, C. H. (1971) Some unique biological characteristics of the Maasai of east Africa. N. Engl. J. Med., 284, 694-699   DOI   ScienceOn
48 Bogin, E. (1991) Low cholesterol eggs. Proceeding of the 4th European symposium on the quality of eggs products. 97
49 Mun, S. H. and Shin, M. S. (2002) The effects of annealing on resistant starch content of cross-linked maize starches. Kor. J. Food Sci. Technol. 34, 431-436   과학기술학회마을
50 배현영 (2006) 콜레스테롤 저하 Camembert cheese 숙성 및 저장 기간 동안의 이화학적 및 관능적 특성에 관한 연구. 세종대학교 석사학위 논문
51 Schroder, B. G. and R. J. Baer. (1990) Utilization of cholesterol-reduced milk fat in flued milks. Food Technol. 16 : 342-347