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Effects of Pork on Cadmium Detoxification in Rats  

Rho Jeong-Hae (Korea Food Research Institute)
Han Chan-Kyu (Korea Food Research Institute)
Seong Ki-Seung (Korea Food Research Institute)
Lee Nam-Hyung (Egg Biotech Corporation)
Publication Information
Food Science of Animal Resources / v.25, no.4, 2005 , pp. 373-382 More about this Journal
Abstract
This study was performed to investigate the effect of pork on the cadmium detoxification in rats. Ninety male Sprague-Dawley strains were divided into five stoups based on cadmium treatment(0, 25, 50, 100, 250 ppm) and cadmium intoxication was observed for 8 weeks. During following 8 weeks, casein was replaced by Pork and the effect of pork was compared with casein. During intoxicating, the growth mte was lessened. Feed efficiency ratio was significantly low, as cadmium intake was high Discontinuing cadmium feeding, the body weights were relieve4 Pork-fed groups seemed to have higher body weight than casein-fed groups. During intoxication, hemoglobin and hematocrit were dependent upon cadmium intake. However, they became normal at detocification stage. Cadmium accumulation of the pour-fed group was lower than that of casein. Especially, the factors which affected the cadmium content in kidney were Cd(p<0.001) and $Cd^*pork(p<0.001)$. Metallothionein(MT) was increased with cadmium, and MT was not likely to be affected by pork. This study may provide scientific background of pork for detoxification from heavy metals such as cadmium.
Keywords
cadmium; pork; rats; cadmium detoxification;
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