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http://dx.doi.org/10.5713/ab.21.0110

Moderate dietary boron supplementation improved growth performance, crude protein digestibility and diarrhea index in weaner pigs regardless of the sanitary condition  

Cho, Hyun Min (Department of Animal Science and Biotechnology, Chungnam National University)
Macelline, Shemil Priyan (Department of Animal Science and Biotechnology, Chungnam National University)
Wickramasuriya, Samiru Sudharaka (Department of Animal Science and Biotechnology, Chungnam National University)
Shin, Taeg Kyun (Department of Animal Science and Biotechnology, Chungnam National University)
Kim, Eunjoo (Department of Animal Science and Biotechnology, Chungnam National University)
Son, Hong Cheol (Department of Animal Science and Biotechnology, Chungnam National University)
Heo, Jung Min (Department of Animal Science and Biotechnology, Chungnam National University)
Publication Information
Animal Bioscience / v.35, no.3, 2022 , pp. 434-443 More about this Journal
Abstract
Objective: The study was conducted to investigate the impact of boron supplementation on nutrient digestibility, inflammatory responses, blood metabolites and diarrhea index, and their relevance to growth performance in weaned pigs housed in good and poor sanitary environments for 14 days after weaning. Methods: A total of 108 male pigs (Duroc×[Yorkshire×Landrace]) weaned at 21 days of age were used in a randomized complete block design with 2×3 factorial arrangement. Pigs were assigned to three boron treatments (0, 5, and 10 mg/kg) under two environments (good and poor sanitary) to give six replicates per treatment (3 pigs per replicate). On 0, 7, and 14 days, one pig per replicate was euthanized to collect, ileum tissue samples, and rectal fecal samples. Results: Boron supplementation quadratically influenced (p<0.001) feed intake and weight gain in pigs housed in good sanitary conditions from 1 to 14 days post-weaning where pigs offered 5 mg/kg boron optimized weight gain and feed intake. There is a quadratic interaction (p = 0.019) on feed intake for 1 to 14 days post-weaning where 5 mg/kg boron increased feed intake in good sanitary conditions. Pigs housed in the poor sanitary environment decreased (p<0.001) villus height and crypt depth in ileum at days 7 and 14. On day 7 and 14, crude protein digestibility was quadratically influenced (p<0.05) by boron supplementation. Boron supplementation linearly increased (p<0.05) plasma calcium and cholesterol levels whilst linearly (p = 0.005) reducing plasma triglyceride concentrations. Diarrhea index was quadratically influenced (p<0.05) by boron supplementations regardless of sanitary conditions where 5 mg/kg boron inclusion achieved the lowest diarrhea index. Conclusion: Pigs offered 5 mg/kg of boron increased weight gain which may be deduced by improved dry matter, crude protein, and energy digestibility regardless of the sanitary conditions.
Keywords
Boron; Diarrhea Index; Pigs; Protein Digestibility;
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1 Ao Z, Kocher A, Choct M. Effects of dietary additives and early feeding on performance, gut development and immune status of broiler chickens challenged with Clostridium perfringens. Asian-Australas J Anim Sci 2012;25:541-51. https://doi.org/10.5713/ajas.2011.11378   DOI
2 Kabay N, Bryjak M. Boron removal from seawater using reverse osmosis integrated processes. In: Kabay N, Bryjak M, Hilal N, et al. Boron separation processes. Amsterdam, Netherland: Elsevier; 2015. pp. 219-35. https://doi.org/10.1019/B978-0-444-63454-2.00009-5   DOI
3 Green D. Effects of boron on selected aspects of swine health related to calcium and phosphorus metabolism. Carbondale, IL, USA: Southern Illinois University; 2020. Available from: https://opensiuc.lib.siu.edu/gs_rp
4 Nielsen FH. Boron in human and animal nutrition. Plant Soil 1997;193:199-208. https://doi.org/10.1023/A:1004276311956   DOI
5 Armstrong TA, Spears JW, Crenshaw TD, Nielsen FH. Boron supplementation of a semipurified diet for weanling pigs improves feed efficiency and bone strength characteristics and alters plasma lipid metabolites. J Nutr 2000;130:2575-81. https://doi.org/10.1093/jn/130.10.2575   DOI
6 Armstrong TA, Spears JW. Effect of dietary boron on growth performance, calcium and phosphorus metabolism, and bone mechanical properties in growing barrows. J Anim Sci 2001;79:3120-7. https://doi.org/10.2527/2001.79123120x   DOI
7 Cheng J, Peng K, Jin E, et al. Effect of additional boron on tibias of African ostrich chicks. Biol Trace Elem Res 2011:144;538-49. https://doi.org/10.1007/s12011-011-9024-y   DOI
8 Bhasker TV, Gowda NKS, Mondal S, et al. Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats. J Trace Elem Med Biol 2016;36:73-9. https://doi.org/10.1016/j.jtemb.2016.04.007   DOI
9 Stein HH, Fuller MF, Moughan PJ, et al. Definition of apparent, true, and standardized ileal digestibility of amino acids in pigs. Livest Sci 2007;109:282-5. https://doi.org/10.1016/j.livsci.2007.01.019   DOI
10 Goldbach HE, Wimmer MA. Boron in plants and animals: is there a role beyond cell-wall structure? J Plant Nutr Soil Sci 2007;170:39-48. https://doi.org/10.1002/jpln.200625161   DOI
11 Kabu M, Uyarlar C, Zarczynska K, Milewska W, Sobiech P. The role of boron in animal health. J Elem 2015;20:535-41. https://doi.org/10.5601/jelem.2014.19.3.706   DOI
12 Armstrong TA, Spears JW, Engle TE, Wright CL. Effect of dietary boron on bone characteristics and plasma parameters in young pigs. In: Roussel AM, Anderson RA, Favier AE, editors. Trace Elements in Man and Animals 10. New York, NY, USA: Springer; 2002. pp. 1067-69. https://doi.org/10.1007/0-306-47466-2_326   DOI
13 Armstrong TA, Flowers WL, Spears JW, Nielsent FH. Long-term effects of boron supplementation on reproductive characteristics and bone mechanical properties in gilts. J Anim Sci 2002;80:154-61. https://doi.org/10.2527/2002.801154x   DOI
14 Shin TK, Yi YJ, Kim JC, et al. Reducing the dietary omega-6 to omega-3 polyunsaturated fatty acid ratio attenuated inflammatory indices and sustained epithelial tight junction integrity in weaner pigs housed in a poor sanitation condition. Anim Feed Sci Technol 2017;234:312-20. https://doi.org/10.1016/j.anifeedsci.2017.04.022   DOI
15 Pineiro C, Pineiro M, Morales J, et al. Pig-MAP and haptoglobin concentration reference values in swine from commercial farms. Vet J 2009;179:78-84. https://doi.org/10.1016/j.tvjl.2007.08.010   DOI
16 Suiryanrayna MV, Ramana JV. A review of the effects of dietary organic acids fed to swine. J Anim Sci Biotechnol 2015;6:45. https://doi.org/10.1186/s40104-015-0042-z   DOI
17 Armstrong TA, Spears JW. Effect of boron supplementation of pig diets on the production of tumor necrosis factor-α and interferon-γ. J Anim Sci 2003;81:2552-61. https://doi.org/10.2527/2003.81102552x   DOI
18 Bialek M, Czauderna M, Krajewska KA, Przybylski W. Selected physiological effects of boron compounds for animals and humans. A review. J Anim Feed Sci 2019;28:307-20. https://doi.org/10.22358/jafs/114546/2019   DOI
19 Humphrey BD, Klasing KC. Modulation of nutrient metabolism and homeostasis by the immune system. World Poult Sci J 2004;60:90-100. https://doi.org/10.1079/WPS20037   DOI
20 Mizrak C, Yenice E, Can M, Yildirim U, Atik Z. Effects of dietary boron on performance, egg production, egg quality and some bone parameters in layer hens. S Afr J Anim Sci 40:257-64. https://doi.org/10.4314/sajas.v40i3.10   DOI
21 Eder K, Stangl GI. Plasma thyroxine and cholesterol concentrations of miniature pigs are influenced by thermally oxidized dietary lipids. J Nutr 2000;130:116-21. https://doi.org/10.1093/jn/130.1.116   DOI
22 Association of Official Analytical Chemists. Official methods of analysis: Changes in Official Methods of Analysis Made at the Annual Meeting. Supplement (Vol. 15). AOAC; 1990.
23 Kim JC, Hansen CF, Mullan BP, Pluske JR. Nutrition and pathology of weaner pigs: nutritional strategies to support barrier function in the gastrointestinal tract. Feed Sci Technol 2012;173:3-16. https://doi.org/10.1016/j.anifeedsci.2011.12.022   DOI
24 National Research Council. Nutrient requirements of swine. 11th ed. Washington, DC, USA: National Academy Press; 2012.
25 Heo JM, Kim JC, Hansen CF, Mullan BP, Hampson DJ, Pluske JR. Feeding a diet with decreased protein content reduces indices of protein fermentation and the incidence of post-weaning diarrhea in weaned pigs challenged with an enterotoxigenic strain of Escherichia coli. J Anim Sci 2009;87:2833-43. https://doi.org/10.2527/jas.2008-1274   DOI
26 Marquardt RR, Jin LZ, Kim JW, Fang L, Frohlich AA, Baidoo SK. Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets. FEMS Immunol Med Microbiol 1999;23:283-8. https://doi.org/10.1111/j.1574-695X.1999.tb01249.x   DOI
27 Field FJ, Albright E, Mathur SN. Effect of dietary cholesterol on biliary cholesterol content and bile flow in the hypothyroid rat. Gastroenterology 1986;91:297-304. https://doi.org/10.1016/0016-5085(86)90560-3   DOI
28 Lairon D. Digestion and absorption of lipids. In: McClements J, Decker EA, editors. Designing functional foods. Woodhead Publishing; 2009. pp. 68-93. https://doi.org/10.1533/9781845696603.1.66   DOI
29 Heo JM, Kim JC, Hansen CF, Mullan BP, Hampson DJ, Pluske JR. Feeding a diet with a decreased protein content reduces both nitrogen content in the gastrointestinal tract and post-weaning diarrhoea, but does not affect apparent nitrogen digestibility in weaner pigs challenged with an enterotoxigenic strain of Escherichia coli. Anim Feed Sci Technol 2010;160:148-59. https://doi.org/10.1016/j.anifeedsci.2010.07.005   DOI
30 Pluske JR, Williams IH, Aherne FX. Maintenance of villous height and crypt depth in piglets by providing continuous nutrition after weaning. Anim Sci 1996;62:131-44. https://doi.org/10.1017/S1357729800014417   DOI
31 Zhao J, Harper AF, Estienne MJ, Webb Jr KE, McElroy AP, Denbow DM. Growth performance and intestinal morphology responses in early weaned pigs to supplementation of antibiotic-free diets with an organic copper complex and spray-dried plasma protein in sanitary and nonsanitary environments. J Anim Sci 2007;85:1302-10. https://doi.org/10.2527/jas.2006-434   DOI