Browse > Article
http://dx.doi.org/10.5713/ab.21.0448

Comparison of organic acids supplementation on the growth performance, intestinal characteristics and morphology, and cecal microflora in broilers fed corn-soybean meal diet  

Sun, Hao Yang (Institute of Animal Nutrition, College of Animal Science and Technology, Northeast Agricultural University)
Zhou, Hong Bin (Dalian Chengsan Animal Husbandry Co., Ltd.)
Liu, Yang (Dalian Chengsan Animal Husbandry Co., Ltd.)
Wang, Yue (Dalian Chengsan Animal Husbandry Co., Ltd.)
Zhao, Cheng (Institute of Animal Nutrition, College of Animal Science and Technology, Northeast Agricultural University)
Xu, Liang Mei (Institute of Animal Nutrition, College of Animal Science and Technology, Northeast Agricultural University)
Publication Information
Animal Bioscience / v.35, no.11, 2022 , pp. 1689-1697 More about this Journal
Abstract
Objective: The aim of this study was to compare the effects of three kinds of organic acid (OA) products on the growth performance, intestinal characteristics and morphology, and cecal microflora in broilers fed a corn-soybean meal meal diet. Methods: A total of 420 one-day-old male Cobb 500 broilers with an average initial body weight of 49.11±1.02 g were used in this 42-day experiment. Birds were randomly allotted to one of five treatments (7 replicates with 12 birds per replicate). Treatments consisted of negative control (NC), basal diet; positive control (PC), basal diet+100 mg/kg of Aviramycin; OA1, basal diet+500 mg/kg of OA product 1; OA2, basal diet+1,000 mg/kg of OA product 2; and OA3, basal diet+1,200 mg/kg of OA product 3. Results: The results indicated that OA product addition had no effect on growth performance parameters, such as body weight gain, feed intake, and feed conversion ratio, from days 1 to 14, 15 to 28, and 0 to 42, or on the pH values of the intestine, intestinal weight, or intestinal weight to body weight ratio. The intestinal morphology in terms of villus height and crypt depth were affected by dietary supplementation of OA products, respectively. Furthermore, dietary addition of OAs had positive influences on the maintenance of the cecal microflora based on the results of 16S rRNA analysis. Conclusion: Dietary inclusion of three kinds of OA products all benefit broilers, but the mode of action may be different. This study provides a basis for the application of OA products used in the poultry industry.
Keywords
Cecal Microflora; Growth Performance; Intestinal Characteristics; Organic Acids;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Tugnoli B, Giovagnoni G, Piva A, Grilli E. From acidifiers to intestinal health enhancers: how organic acids can improve growth efficiency of pigs. Animals (Basel). 2020;10:134. https://doi.org/10.3390/ani10010134   DOI
2 Dittoe DK, Ricke SC, Kiess AS. Organic acids and potential for modifying the avian gastrointestinal tract and reducing pathogens and disease. Front Vet Sci 2018;5:216. https://doi.org/10.3389/fvets.2018.00216   DOI
3 Munyaka PM, Nandha NK, Kiarie E, Nyachoti CM, Khafipour E. Impact of combined β-glucanase and xylanase enzymes on growth performance, nutrients utilization and gut microbiota in broiler chickens fed corn or wheat-based diets. Poult Sci 2016;95:528-40. https://doi.org/10.3382/ps/pev333   DOI
4 Lee KC, Kil DY, Sul WJ. Cecal microbiome divergence of broiler chickens by sex and body weight. J Microbiol 2017;55: 939-45. https://doi.org/10.1007/s12275-017-7202-0   DOI
5 Oakley BB, Buhr RJ, Ritz CW, et al. Successional changes in the chicken cecal microbiome during 42 days of growth are independent of organic acid feed additives. BMC Vet Res 2014;10:282. https://doi.org/10.1186/s12917-014-0282-8   DOI
6 Fassarella M, Blaak EE, Penders J, Nauta A, Smidt H, Zoetendal EG. Gut microbiome stability and resilience: elucidating the response to perturbations in order to modulate gut health. Gut 2020;70:595-605. https://doi.org/10.1136/gutjnl-2020-321747   DOI
7 Adil S, Banday T, Bhat GA, et al. Effect of dietary supplementation of organic acids on performance, intestinal histomorphology, and serum biochemistry of broiler chicken. Vet Med Int 2010;2010:479485. https://doi.org/10.4061/2010/479485   DOI
8 Mohammadagheri N, Najafi R, Najafi G. Effects of dietary supplementation of organic acids and phytase on performance and intestinal histomorphology of broilers. Vet Res Forum 2016;7:189-95.
9 Huang LJ, Zhang KY, Bai SP, et al. Effects of benzoic acid on growth performance and intestinal health of broilers at 1 to 21 days of age. Chinese J Anim Nutr 2019;31:2816-22.
10 Sun HY, Kim IH. Dietary supplementation of mixed yeast culture derived from Saccharomyces cerevisiae and Kluyveromyces maxianus: effects on growth performance, nutrient digestibility, meat quality, blood parameters, and gut health in broilers. J Poult Sci 2019;56:140-7. https://doi.org/10.2141/jpsa.0180052   DOI
11 Jiao Y, Jha R, Zhang WL, Kim IH. Effects of chitooligosaccharide supplementation on egg production, egg quality and blood profiles in laying hens. Indian J Anim Res 2019;53:1199-204.
12 Wang J, Dai D, Zhang HJ, et al. Organic acids modulate systemic metabolic perturbation caused by salmonella pullorum challenge in early-stage broilers. Front Physiol 2019;10:1418. https://doi.org/10.3389/fphys.2019.01418   DOI
13 Patten JD, Waldroup PW. Use of organic acids in broiler diets. Poult Sci 1988;67:1178-82. https://doi.org/10.3382/ps.0671178   DOI
14 Cimrin T, Tunca RI, Avsaroglu MD, Ayasan T, Kucukersan S. Effects of an antibiotic and two phytogenic substances (cinnamaldehyde and 1,8-cineole) on yolk fatty acid profile and storage period-associated egg lipid peroxidation level. Rev Bras Zootec 2020;49:e20190270. https://doi.org/10.37496/rbz4920190270   DOI
15 Edgar RC. Search and clustering orders of magnitude faster than BLAST. Bioinformatics. 2010;26:2460-1. https://doi.org/10.1093/bioinformatics/btq461   DOI
16 Isabel B, Santos Y. Effects of dietary organic acids and essential oils on growth performance and carcass characteristics of broiler chickens. J Appl Poult Res 2009;18:472-6. https://doi.org/10.3382/japr.2008-00096   DOI
17 Yang H, Wang YJ, Feng XJ, et al. Dietary resveratrol alleviates afb1-induced ileum damage in ducks via the nrf2 and nf-κb/nlrp3 signaling pathways and cyp1a1/2 expressions. Agriculture 2022;12:54. https://doi.org/10.3390/agriculture12010054   DOI
18 Giannenas I, Papaneophytou CP, Tsalie E, et al. Dietary supplementation of benzoic acid and essential oil compounds affects buffering capacity of the feeds, performance of turkey poults and their antioxidant status, pH in the digestive tract, intestinal microbiota and morphology. Asian-Australas J Anim Sci 2014;27:225-36. https://doi.org/10.5713/ajas.2013.13376   DOI
19 Houshmand M, Azhar K, Zulkifli I, Bejo MH, Kamyab A. Effects of nonantibiotic feed additives on performance, nutrient retention, gut pH, and intestinal morphology of broilers fed different levels of energy. J Appl Poult Res 2011;20:121-8. https://doi.org/10.3382/japr.2010-00171   DOI
20 Liu WC, Yuan YL, Sun CY, Balasubramanian B, Zhao Z, An L. Effects of dietary betaine on growth performance, digestive function, carcass traits, and meat quality in indigenous yellowfeathered broilers under long-term heat stress. Animals (Basel). 2019;31:506. https://doi.org/10.3390/ani9080506   DOI
21 Magoc T, Salzberg SL. Flash: fast length adjustment of short reads to improve genome assemblies. Bioinformatics 2011;27: 2957-63. https://doi.org/10.1093/bioinformatics/btr507   DOI
22 Agboola AF, Omidiwura BRO, Odu O, Popoola IO, Iyayi EA. Effects of organic acid and probiotic on performance and gut morphology in broiler chickens. South Afr J Anim Sci 2015;45:494-501. https://doi.org/10.4314/sajas.v45i5.6   DOI
23 Gao YY, Zhang XL, Kong QL, Qiu JL, Xu LH, Wang CK. Effects of microencapsulated essential oils and organic acids on growth performance, immune organ indexex, slaughter performance, meat quality and serum biochemical indexes of broilers. Chinese J Anim Nutr 2017;29:2923-30.
24 Ali AM, Seddiek SA, Khater HF. Effect of butyrate, clopidol and their combination on the performance of broilers infected with eimeria maxima. Br Poult Sci 2014;55:474-82. https://doi.org/10.1080/00071668.2014.920488   DOI
25 Zhang L, Wu W, Lee YK, Xie J, Zhang H. Spatial heterogeneity and co-occurrence of mucosal and luminal microbiome across swine intestinal tract. Front Microbiol 2018;9:48. https://doi.org/10.3389/fmicb.2018.00048   DOI
26 Rodjan P, Soisuwan K, Thongprajukaew K, et al. Effect of organic acids or probiotics alone or in combination on growth performance, nutrient digestibility, enzyme activities, intestinal morphology and gut microflora in broiler chickens. J Anim Physiol Anim Nutr (Berl). 2018;102:e931-40. https://doi.org/10.1111/jpn.12858   DOI
27 Broom LJ. Organic acids for improving intestinal health of poultry. Worlds Poult Sci J 2015;71:630-42. https://doi.org/10.1017/S0043933915002391   DOI
28 Zhong LM, Li DD, Zhang KY, et al. Effects of wheat grinding particle size on production performance, digestibe rogan development and intestinal health of broilers in meal diets. J Sichuan Agric Univ 2018;36:100-7.
29 Chowdhury R, Islam KMS, Khan MJ, et al. Effect of citric acid, avilamycin, and their combination on the performance, tibia ash, and immune status of broilers. Poult Sci 2009;88:1616-22. https://doi.org/10.3382/ps.2009-00119   DOI
30 Sabour S, Tabeidian SA, Sadeghi G. Dietary organic acid and fiber sources affect performance, intestinal morphology, immune responses and gut microflora in broilers. Anim Nutr 2019;5:156-62. https://doi.org/10.1016/j.aninu.2018.07.004   DOI
31 Liu YM, Zhi SQ, Lan WK, Zhan XS, Zhang HH. Effects of compound acidifier on growth performance and serum biochemical indexes of white-feather broiler. China Poult 2019;41:24-7.
32 Nguyen DH, Kim IH. Protected organic acids improved growth performance, nutrient digestibility, and decreased gas emission in broilers. Animals 2020;10:416. https://doi.org/10.3390/ani10030416   DOI
33 Peng YZ, Wang XK, Song ML, et al. Effects of mixed acidifier on intestinal morphology and caecum microbial flora of broilers. China Poult 2020;42:52-8.
34 SAS Institute Inc, SAS System for Windows computer program, Version 9.10. 2009. Cary, NC, USA: SAS Institute Inc; 2009.
35 Lan RX, Li SQ, Zhao Z, An LL. Sodium butyrate as an effective feed additive to improve growth performance and gastrointestinal development in broilers. Vet Med Sci 2020;6:491-9. https://doi.org/10.1002/vms3.250   DOI
36 Ju TT, Guo XY, Xiao X, et al. Effects of sodium butyrate on growth performance, serum biochemical indicators, digestive function and intestinal morphology in broilers. China Poult 2015;37:32-6.
37 Hu Y, Wang L, Shao D, et al. Selectived and reshaped early dominant microbial community in the cecum with similar proportions and better homogenization and species diversity due to organic acids as agp alternatives mediate their effects on broilers growth. Front Microbiol 2020;10:2948. https://doi.org/10.3389/fmicb.2019.02948   DOI