Browse > Article
http://dx.doi.org/10.5713/ajas.19.0934

Vitamin E improves antioxidant status but not lipid metabolism in laying hens fed a aged corn-containing diet  

Ding, X.M. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Mu, Y.D. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Zhang, K.Y. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Wang, J.P. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Bai, S.P. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Zeng, Q.F. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Peng, H.W. (Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Key laboratory of Animal Disease-resistant Nutrition)
Publication Information
Animal Bioscience / v.34, no.2, 2021 , pp. 276-284 More about this Journal
Abstract
Objective: The objective of this study was to determine whether a dietary vitamin E (VE) supplement could alleviate any detrimental effects of aged corn on lipid metabolism and antioxidant status in laying hens. Methods: The experiment consisted of a 2×3 factorial design with two corn types (normal corn and aged corn (stored for 4 yr) and three concentrations of VE (0, 20, and 100 IU/kg). A total of 216 Lohmann laying hens (50 wk of age) were randomly allocated into six treatment diets for 12 wk. Each treatment had 6 replicates of 6 hens per replicate. Results: The results show that aged corn significantly decreased the content of low-density lipoprotein cholesterol (p<0.05), and reduced chemokine-like receptor 1 (CMKLR1) mRNA expression (p<0.05) in the liver compared to controls. Diet with VE did not alter the content of crude fat and cholesterol (p>0.05), or acetyl-CoA carboxylase, lipoprotein lipase, fatty acid synthase or CMKLR1 mRNA expression (p>0.05) in the liver among treatment groups. Aged corn significantly increased the content of malondialdehyde (MDA) (p<0.05) and decreased superoxide dismutase (SOD) activity (p<0.05) in the liver. The VE increased the content of MDA (p<0.05) but decreased glutathione peroxidase (GSH-Px) activity in serum (p<0.01) and in the ovaries (p<0.05). Adding VE at 20 and 100 IU/kg significantly increased GSH-Px activity (p<0.05) in liver and in serum (p<0.01), 100 IU/kg VE significantly increased SOD activity (p<0.05) in serum. Aged corn had no significant effects on GSH-Px mRNA or SOD mRNA expression (p<0.01) in the liver and ovaries. Addition of 100 IU/kg VE could significantly increase SOD mRNA expression (p<0.01) in the liver and ovary. Conclusion: Aged corn affected lipid metabolism and decreased the antioxidant function of laying hens. Dietary VE supplementation was unable to counteract the negative effects of aged corn on lipid metabolism. However, addition of 100 IU/kg VE prevented aged corninduced lipid peroxidation in the organs of laying hens.
Keywords
Vitamin E; Aged Corn; Lipid Metabolism; Antioxidant; Laying Hens;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Parlee SD, Ernst MC, Muruganandan S, Sinal CJ, Goralski KB. Serum chemerin levels vary with time of day and are modified by obesity and tumor necrosis factor-α. Endocrinology 2010;151:2590-602. https://doi.org/10.1210/en.2009-0794   DOI
2 Wanninger J, Bauer S, Eisinger K, et al. Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver. Mol Cell Endocrinol 2012;349:248-54. https://doi.org/10.1016/j.mce.2011.10.032   DOI
3 Choct M, Hughes RJ. The new season grain phenomenon: the role of endogenous glycanases in the nutritive value of cereal grains in broiler chickens. Australia: Rural Industries Research and Development Corporation; 2000.
4 McDonough CM, Floyd CD, Waniska RD, Rooney LW. Effect of accelerated aging on maize, sorghum, and sorghum meal. J Cereal Sci 2004;39:351-61. https://doi.org/10.1016/j.jcs.2004.01.001   DOI
5 Burton GW, Traber MG. Vitamin E: antioxidant activity, biokinetics, and bioavailability. Annu Rev Nutr 1990;10:357-82. https://doi.org/10.1146/annurev.nu.10.070190.002041   DOI
6 Bauer S, Wanninger J, Schmidhofer S, et al. Sterol regulatory element-binding protein 2 (SREBP2) activation after excess triglyceride storage induces chemerin in hypertrophic adipocytes. Endocrinology 2011;152:26-35. https://doi.org/10.1210/en.2010-1157   DOI
7 Ng CY, Leong XF, Masbah N, et al. Reprint of "heated vegetable oils and cardiovascular disease risk factors". Vasc Pharmacol 2014;62:38-46. https://doi.org/10.1016/j.vph.2014.05.003   DOI
8 Wang J, Zhang HJ, Xu L, et al. Dietary supplementation of pyrroloquinoline quinone disodium protects against oxidative stress and liver damage in laying hens fed an oxidized sunflower oil-added diet. Animal 2016;10:1129-36. https://doi.org/10.1017/S175173111600001X   DOI
9 Galliard T. Hydrolytic and oxidative degradation of lipids during storage of wholemeal flour: effects of bran and germ components. J Cereal Sci 1986;4:179-92. https://doi.org/10.1016/S0733-5210(86)80020-0   DOI
10 Rehman ZU. Storage effects on nutritional quality of commonly consumed cereals. Food Chem 2006;95:53-7. https://doi.org/10.1016/j.foodchem.2004.12.017   DOI
11 Bailly C, Bogatek-Leszczynska R, Come D, Corbineau F. Changes in activities of antioxidant enzymes and lipoxygenase during growth of sunflower seedlings from seeds of different vigour. Seed Sci Res 2002;12:47-55. https://doi.org/10.1079/SSR200197   DOI
12 Liu B, He YY, Yin DF, Xia ZF, Yuan JM. Corn at different storage periods affects serum antioxidant function of broilers. Chin J Anim Nutr 2013;25:1077-84.   DOI
13 McFarlane JM, Curtis SE, Shanks RD, Carmer SG. Multiple concurrent stressors in chicks.: 1. Effect on weight gain, feed intake, and behavior. Poult Sci 1989;68:501-9. https://doi.org/10.3382/ps.0680501   DOI
14 Attia YA, Abd El-Hamid AE, Abdallah AA, et al. Effect of betaine, vitamin C and vitamin E on egg quality, hatchability, and markers of liver and renal functions in dual-purpose breeding hens exposed to chronic heat stress. Eur Poult Sci 2018;82:226. https://doi.org/10.1399/eps.2018.226   DOI
15 Zhang YR, Wang Z, Cai SM, et al. Effects of aging corn diet supplemented with tea polyphenol, vitamin E and butylated hydroxytoluene on growth performance and antioxidant function of meat ducks. Chin J Anim Nutr 2015;27:1184-90.
16 Jiang W, Zhang L, Shan A. The effect of vitamin E on laying performance and egg quality in laying hens fed corn dried distillers grains with solubles. Poult Sci 2013;92:2956-64. https://doi.org/10.3382/ps.2013-03228   DOI
17 Chrastil J. Protein-starch interactions in rice grains. Influence of storage on oryzenin and starch. J Agric Food Chem 1990;38:1804-9. https://doi.org/10.1021/jf00099a005   DOI
18 Lu T, Harper AF, Dibner JJ, et al. Supplementing antioxidants to pigs fed diets high in oxidants: II. Effects on carcass characteristics, meat quality, and fatty acid profile. J Anim Sci 2014;92:5464-75. https://doi.org/10.2527/jas.2013-7112   DOI
19 Mu Y, Zhang K, Bai S, Wang JP, Zeng Q, Ding X. Effects of vitamin E supplementation on performance, serum biochemical parameters and fatty acid composition of egg yolk in laying hens fed a diet containing ageing corn. J Anim Physiol Anim Nutr 2019;103:135-45. https://doi.org/10.1111/jpn.13017   DOI
20 Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 2001;25:402-8. https://doi.org/10.1006/meth.2001.1262   DOI
21 Zhang Y, Zhou X, Zhang Y. Research on membrane lipid peroxidation and physiological parameters of storage maize. Sci Agric Sin 2008;41:3410-4.
22 Elkin RG. Reducing shell egg cholesterol content. I. Overview, genetic approaches, and nutritional strategies. Worlds Poult Sci J 2006;62:665-87. https://doi.org/10.1017/S0043933906001206   DOI
23 Chao PM, Chao CY, Lin FJ, Huang C. Oxidized frying oil up-regulates hepatic acyl-CoA oxidase and cytochrome P450 4 A1 genes in rats and activates PPARα. J Nutr 2001;131:3166-74. https://doi.org/10.1093/jn/131.12.3166   DOI
24 Yoshimura T, Oppenheim JJ. Chemokine-like receptor 1 (CMKLR1) and chemokine (C-C motif) receptor-like 2 (CCRL2); two multifunctional receptors with unusual properties. Exp Cell Res 2011;317:674-84. https://doi.org/10.1016/j.yexcr.2010.10.023   DOI
25 Yue HY, Wang J, Qi XL, et al. Effects of dietary oxidized oil on laying performance, lipid metabolism, and apolipoprotein gene expression in laying hens. Poult Sci 2011;90:1728-36. https://doi.org/10.3382/ps.2011-01354   DOI
26 Casamassima D, Nardoia M, Palazzo M, Vizzarri F, Corino C. Effect of dietary extruded linseed, verbascoside and vitamin E supplements on selected serum biochemical parameters and plasma oxidative status in lacaune ewes. Slov Vet Res 2014;51:89-100.
27 Dou M, Ma AG, Wang QZ, et al. Supplementation with magnesium and vitamin E were more effective than magnesium alone to decrease plasma lipids and blood viscosity in diabetic rats. Nutr Res 2009;29:519-24. https://doi.org/10.1016/j.nutres.2009.07.001   DOI
28 Ammouche A, Rouaki F, Bitam A, Bellal MM. Effect of ingestion of thermally oxidized sunflower oil on the fatty acid composition and antioxidant enzymes of rat liver and brain in development. Ann Nutr Metab 2002;46:268-75. https://doi.org/10.1159/000066496   DOI
29 Koch A, Konig B, Spielmann J, Leitner A, Stangl GI, Eder K. Thermally oxidized oil increases the expression of insulin-induced genes and inhibits activation of sterol regulatory element-binding protein-2 in rat liver. J Nutr 2007;137:2018-23. https://doi.org/10.1093/jn/137.9.2018   DOI