Browse > Article
http://dx.doi.org/10.9708/jksci.2019.24.09.103

Analysing Risk Factors of 5-Year Survival Colorectal Cancer Using the Network Model  

Park, Won Jun (Dept. of Computer Engineering, Gachon University)
Lee, Young Ho (Dept. of Computer Engineering, Gachon University)
Kang, Un Gu (Dept. of Computer Engineering, Gachon University)
Publication Information
Journal of the Korea Society of Computer and Information / v.24, no.9, 2019 , pp. 103-108 More about this Journal
Abstract
The purpose of this study is to identify the factors that may affect the 5-year survival of colon cancer through network model and to use it as a clinical decision supporting system for colorectal cancer patients. This study was conducted using data from 2,540 patients who underwent colorectal cancer surgery from 1996 to 2018. Eleven factors related to survival of colorectal cancer were selected by consulting medical experts and previous studies. Analysis was proceeded from the data sorted out into 1,839 patients excluding missing values and outliers. Logistic regression analysis showed that age, BMI, and heart disease were statistically significant in order to identify factors affecting 5-year survival of colorectal cancer. Additionally, a correlation analysis was carried out age, BMI, heart disease, diabetes, and other diseases were correlated with 5-year survival of colorectal cancer. Sex was related with BMI, lung disease, and liver disease. Age was associated with heart disease, heart disease, hypertension, diabetes, and other diseases, and BMI with hypertension, diabetes, and other diseases. Heart disease was associated with hypertension, diabetes, hypertension, diabetes, and other diseases. In addition, diabetes and kidney disease were associated. In the correlation analysis, the network model was constructed with the Network Correlation Coefficient less than p <0.001 as the weight. The network model showed that factors directly affecting survival were age, BMI levels, heart disease, and indirectly influencing factors were diabetes, high blood pressure, liver disease and other diseases. If the network model is used as an assistant indicator for the treatment of colorectal cancer, it could contribute to increasing the survival rate of patients.
Keywords
Colorectal Cancer; Logistic Regression Analysis; Correlation Analysis; Network Model;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
연도 인용수 순위
1 P. J. Oh, and J. H. Kim, "Chemotherapy-related Cognitive Impairment and Quality of Life in People with Colon Cancer: The Mediating Effect of Psychological Distress," Journal of Korean Academy of Nursing, Vol. 46, No. 1, pp.19-28, Feb, 2016.   DOI
2 Y. A. Baek. and M. S. Yi, "Factors Influencing Quality of Life during Chemotherapy for Colorectal Cancer Patients in South Korea," Journal of Korean Academy of Nursing, Vol. 45, No. 4, pp.604-612, Aug. 2015.   DOI
3 B. M. Kang, G. S. Choi, K. H. Lim, I. J. Park, and S. H. Jun, "Risk Factors of Peritoneal Recurrence after Curative Resection of Colorectal Cancer," Annals of Surgical Treatment and Research, Vol. 79, No. 5, pp.355-361, Aug. 2010.   DOI
4 S. J. Joeng, S. Y. Ryu, H. R. Kim, D. Y. Kim, and Y. J. Kim, "Multivariate analysis of prognostic factors in colorectal cancers," Annals of Surgical Treatment and Research, Vol. 61, No. 2, pp.173-178, Aug. 2001.
5 S. W. Park, D. W. Lee, J. W. Park, S. B. Ryoo, R. Shin, S. Y. Jeong, and K. Y. Park, "Impact of body mass index on overall survival after surgery for colorectal cancer," Korean Journal of Clinical Oncology, Vol. 12, No. 2, pp.91-96, Dec. 2016.   DOI
6 Y. G. Park, B. S. Cho, Y. D. Yoon, Y. J. Kang, and J. S. Park, "Analysis of the survival rate after operations for colorectal cancer," Annals of Surgical Treatment and Research, Vol. 55, No. 4, pp.540-548, Oct. 1998.
7 C. H. Lee, "Fine-Grain Weighted Logistic Regression Model," The Institute of Electronics and Information Engineers, Vol. 53, No. 9, pp.77-81, Jul. 2016.   DOI
8 H. J. Byung, and D. H. Lim, "Performance Comparison of Logistic Regression Algorithms on RHadoop," Journal of the Korea Society of Computer and Information, Vol. 22, No. 4, pp.9-16, Apr. 2017.   DOI
9 C. H. Lee, and M. N. Jung, "Value Weighted Regularized Logistic Regression Model," Journal of the Korea Society of Computer and Information, Vol. 43, No. 11, pp.1270-1274, Nov. 2016.
10 M. S. Choi, "An Analysis about Recognition of Indoor Air Quality of Workers at Dental Clinics in Jeollanamdo Area," Journal of the Korea Society of Computer and Information, Vol. 23, No. 11, pp.137-142, Nov. 2018.   DOI
11 Y. T. Kwak, "A Layer-by-Layer Learning Algorithm using Correlation Coefficient for Multilayer Perceptrons,"Journal of the Korea Society of Computer and Information, Vol. 16, No. 8, pp.39-47, Aug. 2011.   DOI
12 G. C. Lee, and S. W. Youn, "Smart Speaker Market Analysis and Forecast using Google Trends," KIISE Transactions on Computing Practices, Vol. 24, No. 11, pp.596-602, Nov. 2018.   DOI
13 M. N Lee, and J. H. Hong, "Semantic Network Analysis of Government"s Crisis Communication Messages during the MERS Outbreak," The Journal of the Korea Contents Association, Vol. 16, No. 5, pp.124-136, May. 2016.   DOI
14 Y. B. Park, and S. E. Moon, "A clinical study of colorectal cancer," Annals of Surgical Treatment and Research, Vol. 46, No. 2, pp242-249, Jun. 1994.
15 B. P. Kim, K. H. Kwon, and H. S. Min, "A clinical study of colorectal cancer," Annals of Surgical Treatment and Research, Vol. 54, No. 3, pp.374-382, Oct. 1998.
16 H. S. Kim, and N. C. Kim, "Difference of the Obesity Index, Blood Pressure and Serum Lipids in Abdominal and Non Abdominal in Men and Women," Journal of Korean Academy of Nursing, Vol. 30, No. 4, pp. 948-955, Aug. 2000.   DOI
17 Y. Moriwaki, C. Kunisaki, S. Kobayashi, H. Harada, S. Imai and C. Kasaoka, "Does body mass index (BMI) influence morbidity and long-term survival in gastric cancer patients after gastrectomy?," Journal of Hepato Gastroenterology, Vol. 50, No. 49, pp.284-288, Jan. 2003.
18 C. Eroglu, O. Orhan, H. Karaca, D. Unal, M. Dikilitas, M. Ozkan, et al., "The effect of being overweight on survival in patients with gastric cancer undergoing adjuvant chemoradiotherapy," European Journal of Cancer Care, Vol. 22, No. 1, pp.133-140, Sep. 2012.   DOI
19 N. M. Tsang, P. C. Pai, C. C. Chuang, W. C. Chuang, C. K. Tseng, K. P. Chang, et al., "Overweight and obesity predict better overall survival rates in cancer patients with distant metastases," Journal of Cancer Medicine, Vol. 5, No. 4, pp.665-675, Jan. 2016.   DOI
20 C. H. Kroenke, R. Neugebauer, J. Meyerhardt, C. M. Prado, E. Weltzien, M. L. Kwan, et al., "Analysis of body mass index and mortality in patients with colorectal cancer using causal diagrams," JAMA Oncology, Vol. 2, No. 9, pp.1137-1145, Sep. 2016.   DOI
21 Y. G. Yoo, Y. R. Park, and E. H. Choi, "A Comparative Study of Life Styles between Lung Cancer Patients and Healthy Adults," Asian Oncology Nursing, Vol. 13, No. 3, pp.136-144, Sep. 2013.   DOI
22 H. J. Lee, and H. S. Park "Experience of Patients' Management of Hepatocellular Carcinoma with Transarterial Chemoembolization," Journal of Qualitative Research, Vol 18, No. 12, pp.78-92, May. 2015.
23 S. S. Kim, "The effect of a long term aerobic training on blood lipid profiles and body fat in hypertensive obesity and diabetic obesity patients," Journal of Sport and Leisure Studies, Vol. 11, No. pp.183-193, Nov. 1999
24 D. G. Shin, S. H. Seong, W. S. Kim, and D. S. Kim, "The Effect of Old Age on the Development of Postoperative Complication in Surgery for Gastric Carcinoma," Annals of Surgical Treatment and Research, Vol. 69, No. 6, pp.455-458, May. 2005.
25 S. B. Lee, and S. Y. Park, "Effects of body fat and physical activity habit on cardiovascular risk factors in type 2 diabetic subjects," KSW, Vol. 7, No. 3, pp.237-248, May. 2012.
26 C. G. Kim, "Effect of Health Behavior and Obesity Indices on Blood Pressure in 20s Man," The Journal of the Korea Contents Association, Vol. 11, No. 8, pp.231-238, Aug. 2011.   DOI
27 H. S. Park, H. Cho, and H. S. Kim, "Development of an Evidence-based Nursing Process System to Improve Clinical Decision Making with Colorectal Cancer Nursing Diagnosis," Journal of Korea Multimedia Society, Vol. 19, No. 7, pp.1197-1207, Jul. 2016.   DOI
28 D. N. Son, S. W. Moon, D. Y. Ha, H. G. Jung, and B. W. Jung, "The Level of Serum CEA Associated with Recurrence after Potentially Curative Surgery for Colorectal Cancer," Annals of Surgical Treatment and Research, Vol. 75, No. 4, pp. 250-254, Oct. 2008.