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http://dx.doi.org/10.9708/jksci.2015.20.4.069

Application of Hyperspectral Imaging System to Analyze Vascular Alteration for Preclinical Models  

Choe, Se-Woon (Department of Biomedical Engineering, Tongmyong University)
Woo, Young Woon (Department of Multimedia Engineering, Dong-Eui University)
Publication Information
Journal of the Korea Society of Computer and Information / v.20, no.4, 2015 , pp. 69-76 More about this Journal
Abstract
We present microscopy based hyperspectral imaging system that successively shows high spatial (micrometer) and temporal resolutions (milisecond), and acquired pseudocolor hemoglobin saturation map a result of various image processing techniques can provide additional information such as oxygen transport, abnormal vascularity and therapeutic effects besides structural and physiological measurements in various diseases. To increase understanding of vascular defects several optical methods of imaging for preclinical/clinical assessment have been developed so far. However, they have some limitations for outcoming resolution and user satisfaction level compared to its cost. A hyperspectral imaging system has shown a wide range of vascular characteristics associated with hypervascularity, aberrant angiogenesis or abnormal vascular remodeling in many diseases. This vascular characteristic is considered as a key component to diagnose and detect a type of disease as evidenced by them.
Keywords
Hyperspectral imaging; Vascularization; Hemoglobin saturation; Image processing;
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