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http://dx.doi.org/10.7744/kjoas.20220068

Prospects of omics-driven synthetic biology for sustainable agriculture  

Soyoung Park (Department of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration)
Sung-Dug Oh (Department of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration)
Vimalraj Mani (Department of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration)
Jin A Kim (Department of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration)
Kihun Ha (Department of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration)
Soo-Kwon Park (Crop Foundation Research Division, National Institute of Crop Science, Rural Development Administration)
Kijong Lee (Department of Agricultural Biotechnology, National Institute of Agricultural Sciences, Rural Development Administration)
Publication Information
Korean Journal of Agricultural Science / v.49, no.4, 2022 , pp. 749-760 More about this Journal
Abstract
Omics-driven synthetic biology is a multidisciplinary research field that creates new artificial life by employing genetic components, biological devices, and engineering technique based on genetic knowledge and technological expertise. It is also utilized to make valuable biomaterials with limited production via current organisms faster, more efficient, and in huge quantities. As the bioeconomic age begins, and the global synthetic biology market becomes more competitive, investment in research and development (R&D) and associated sectors has grown considerably. By overcoming the constraints of present biotechnologies through the merging of big data and artificial intelligence technologies, huge ripple effects are envisaged in the pharmaceutical, chemical, and energy industries. In agriculture, synthetic biology is being used to solve current agricultural problems and develop sustainable agricultural systems by increasing crop productivity, implementing low-carbon agriculture, and developing plant-based, high-value-added bio-materials such as vaccines for diagnosing and preventing livestock diseases. As international regulatory debates on synthetic biology are now underway, discussions should also take place in our country for the growth of bioindustries and the dissemination of research findings. Furthermore, the system must be improved to facilitate practical application and to enhance the risk evaluation technology and management system.
Keywords
agriculture; biotechnology; metabolomics; omics; synthetic biology;
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