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http://dx.doi.org/10.7744/cnujas.2010.37.3.543

Interactions of Phospholipid Liposomes and Bovine Lactoferrin  

Kim, Mi-Young (Department of Chemistry, Pusan National University)
Kang, Shin-Won (Department of Chemistry, Pusan National University)
Park, Jang-Su (Department of Chemistry, Pusan National University)
Nam, Myoung-Soo (Lab. of Milk Food Biochemistry, Chungnam National University)
Publication Information
Korean Journal of Agricultural Science / v.37, no.3, 2010 , pp. 543-545 More about this Journal
Abstract
Apo, holo, native-type of lactoferrin showed a similar pattern of circular dichroism(CD) spectra. Lactoferrin appeared to interact more easily with negatively charged liposome than neutral liposome. Holo-type of lactoferrin showed the highest degree of leakage, whereas apo-type of lactoferrin showed the lowest level of leakage. Holo-type lactoferrin could more easily interact with phospholipid liposomes than apo-type lactoferrin, when used as an artificial membrane.
Keywords
Apo-lactoferrin; CD spectra; Holo-lactoferrin; Phospholipid liposome;
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