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http://dx.doi.org/10.4041/kjod.2018.48.6.395

Association between genetic polymorphisms and external apical root resorption: A systematic review and meta-analysis  

Nowrin, Shifat A (Orthodontic Unit, School of Dental Sciences, Universiti Sains Malaysia)
Jaafar, Saidi (Craniofacial Biology Research Group, School of Dental Sciences, Universiti Sains Malaysia)
Rahman, Norma Ab (Orthodontic Unit, School of Dental Sciences, Universiti Sains Malaysia)
Basri, Rehana (Department of Medicine, College of Medicine, Al Jouf University)
Alam, Mohammad Khursheed (Orthodontic Unit, College of Dentistry, Al Jouf University)
Shahid, Fazal (Orthodontic Unit, School of Dental Sciences, Universiti Sains Malaysia)
Publication Information
The korean journal of orthodontics / v.48, no.6, 2018 , pp. 395-404 More about this Journal
Abstract
Objective: To date, only a few studies have investigated the relationships between genetic polymorphisms and external apical root resorption (EARR). Hence, the aim of this systematic review was to explore the relationship between different gene polymorphisms and their association with EARR. Methods: A complete literature search was conducted by two independent reviewers. The PubMed, Science Direct, and Scopus databases were searched. In addition, the bibliographies of all textbooks and relevant articles were searched manually. A meta-analysis was performed using data entered into the electronic databases until February 28, 2017. Results: On the basis of the search, we identified 17 and 7 publications for the systematic review and meta-analysis, respectively. Odds ratio (OR) was used to evaluate the association of the interleukin 1B (+3954) polymorphism and the risk of EARR. The overall OR from the studies was used to estimate the risk of EARR. However, no association was found and no publication bias was apparent for the risk of EARR in patients receiving orthodontic treatment. Conclusions: More research on the relationship between gene polymorphism and EARR is necessary to determine better specificity of possible interactions.
Keywords
Genetics; Root resorption; Tooth movement; Evidence-based orthodontics;
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1 Wehrbein H, Fuhrmann RA, Diedrich PR. Human histologic tissue response after long-term orthodontic tooth movement. Am J Orthod Dentofacial Orthop 1995;107:360-71.   DOI
2 Parker RJ, Harris EF. Directions of orthodontic tooth movements associated with external apical root resorption of the maxillary central incisor. Am J Orthod Dentofacial Orthop 1998;114:677-83.   DOI
3 Brezniak N, Wasserstein A. Orthodontically induced inflammatory root resorption. Part I: the basic science aspects. Angle Orthod 2002;72:175-9.
4 Harris EF, Kineret SE, Tolley EA. A heritable component for external apical root resorption in patients treated orthodontically. Am J Orthod Dentofacial Orthop 1997;111:301-9.   DOI
5 Al-Qawasmi RA, Hartsfield JK Jr, Everett ET, Flury L, Liu L, Foroud TM, et al. Genetic predisposition to external apical root resorption. Am J Orthod Dentofacial Orthop 2003;123:242-52.   DOI
6 Fontana ML, de Souza CM, Bernardino JF, Hoette F, Hoette ML, Thum L, et al. Association analysis of clinical aspects and vitamin D receptor gene polymorphism with external apical root resorption in orthodontic patients. Am J Orthod Dentofacial Orthop 2012;142:339-47.   DOI
7 Gulden N, Eggermann T, Zerres K, Beer M, Meinelt A, Diedrich P. Interleukin-1 polymorphisms in relation to external apical root resorption (EARR). J Orofac Orthop 2009;70:20-38.   DOI
8 Iglesias-Linares A, Yanez-Vico RM, Ballesta S, Ortiz-Ariza E, Mendoza-Mendoza A, Perea E, et al. Interleukin 1 gene cluster SNPs (rs1800587, rs1143634) influences post-orthodontic root resorption in endodontic and their contralateral vital control teeth differently. Int Endod J 2012;45:1018-26.   DOI
9 Iglesias-Linares A, Yanez-Vico RM, Moreno-Fernandez AM, Mendoza-Mendoza A, Orce-Romero A, Solano-Reina E. Osteopontin gene SNPs (rs9138, rs11730582) mediate susceptibility to external root resorption in orthodontic patients. Oral Dis 2014;20:307-12.   DOI
10 Tomoyasu Y, Yamaguchi T, Tajima A, Inoue I, Maki K. External apical root resorption and the interleukin-1B gene polymorphism in the Japanese population. Orthod Waves 2009;68:152-7.   DOI
11 Roscoe MG, Meira JB, Cattaneo PM. Association of orthodontic force system and root resorption: A systematic review. Am J Orthod Dentofacial Orthop 2015;147:610-26.   DOI
12 Aminoshariae A, Aminoshariae A, Valiathan M, Kulild JC. Association of genetic polymorphism and external apical root resorption. Angle Orthod 2016;86:1042-9.   DOI
13 Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977;33:159-74.   DOI
14 Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994;50:1088-101.   DOI
15 Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.   DOI
16 Guo Y, He S, Gu T, Liu Y, Chen S. Genetic and clinical risk factors of root resorption associated with orthodontic treatment. Am J Orthod Dentofacial Orthop 2016;150:283-9.   DOI
17 Bastos Lages EM, Drummond AF, Pretti H, Costa FO, Lages EJ, Gontijo AI, et al. Association of functional gene polymorphism IL-1beta in patients with external apical root resorption. Am J Orthod Dentofacial Orthop 2009;136:542-6.   DOI
18 Iglesias-Linares A, Yanez-Vico RM, Ballesta-Mudarra S, Ortiz-Ariza E, Mendoza-Mendoza A, Perea-Perez E, et al. Interleukin 1 receptor antagonist (IL1RN) genetic variations condition post-orthodontic external root resorption in endodontically-treated teeth. Histol Histopathol 2013;28:767-73.
19 Iglesias-Linares A, Yanez-Vico RM, Ortiz-Ariza E, Ballesta S, Mendoza-Mendoza A, Perea E, et al. Postorthodontic external root resorption in rootfilled teeth is influenced by interleukin-1b polymorphism. J Endod 2012;38:283-7.   DOI
20 Iglesias-Linares A, Yanez-Vico R, Ballesta-Mudarra S, Ortiz-Ariza E, Ortega-Rivera H, Mendoza-Mendoza A, et al. Postorthodontic external root resorption is associated with IL1 receptor antagonist gene variations. Oral Dis 2012;18:198-205.   DOI
21 Pereira S, Lavado N, Nogueira L, Lopez M, Abreu J, Silva H. Polymorphisms of genes encoding P2X7R, IL-1B, OPG and RANK in orthodontic-induced apical root resorption. Oral Dis 2014;20:659-67.   DOI
22 Pereira S, Nogueira L, Canova F, Lopez M, Silva HC. IRAK1 variant is protective for orthodontic-induced external apical root resorption. Oral Dis 2016;22:658-64.   DOI
23 Sharab LY, Morford LA, Dempsey J, Falcao-Alencar G, Mason A, Jacobson E, et al. Genetic and treatmentrelated risk factors associated with external apical root resorption (EARR) concurrent with orthodontia. Orthod Craniofac Res 2015;18 Suppl 1:71-82.   DOI
24 Linhartova P, Cernochova P, Izakovicova Holla L. IL1 gene polymorphisms in relation to external apical root resorption concurrent with orthodontia. Oral Dis 2013;19:262-70.   DOI
25 Manolagas SC, Jilka RL. Cytokines, hematopoiesis, osteoclastogenesis, and estrogens. Calcif Tissue Int 1992;50:199-202.   DOI
26 Pan Z, Trikalinos TA, Kavvoura FK, Lau J, Ioannidis JP. Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature. PLoS Med 2005;2:e334.   DOI
27 Roodman GD. Role of cytokines in the regulation of bone resorption. Calcif Tissue Int 1993;53 Suppl 1:S94-8.   DOI
28 Gowen M, Wood DD, Ihrie EJ, McGuire MK, Russell RG. An interleukin 1 like factor stimulates bone resorption in vitro. Nature 1983;306:378-80.   DOI
29 Segal GR, Schiffman PH, Tuncay OC. Meta analysis of the treatment-related factors of external apical root resorption. Orthod Craniofac Res 2004;7:71-8.   DOI
30 Al-Qawasmi RA, Hartsfield JK Jr, Everett ET, Flury L, Liu L, Foroud TM, et al. Genetic predisposition to external apical root resorption in orthodontic patients: linkage of chromosome-18 marker. J Dent Res 2003;82:356-60.   DOI
31 Linhartova P, Cernochova P, Kastovsky J, Vrankova Z, Sirotkova M, Izakovicova Holla L. Genetic determinants and postorthodontic external apical root resorption in Czech children. Oral Dis 2017;23:29-35.   DOI