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http://dx.doi.org/10.7464/ksct.2011.17.3.273

Toxicity Analysis of Carbon Nanotubes Based on Their Physicochemical Properties  

Kim, Soo-Nam (Inhalation Toxicology Center, KIT Jeongeup Campus)
Kang, Min-Sung (Inhalation Toxicology Center, KIT Jeongeup Campus)
Han, Young-Ah (Inhalation Toxicology Center, KIT Jeongeup Campus)
Kim, Jae-Hwan (Inhalation Toxicology Center, KIT Jeongeup Campus)
Roh, Jin-Kyu (Department of Chemical Engineering, Kwangwoon University)
Kim, Young-Hun (Department of Chemical Engineering, Kwangwoon University)
Choi, Sang-Dun (Department of Molecular Science and Technology, Ajou University)
Park, Eun-Jung (Department of Molecular Science and Technology, Ajou University)
Publication Information
Clean Technology / v.17, no.3, 2011 , pp. 273-279 More about this Journal
Abstract
The physicochemical properties of manufactured nanomaterials can vary depending upon the methods of manufacture, although the utilized raw materials are same. Hence, the toxicity can also vary based on the methods of nanomaterials manufacture. In this study, we compared the toxicity effect of two types of CNTs (MWCNT, multi-walled carbon nanotube; SWCNT, single-walled carbon nanotube) that differ in length and wall number. In case of MWCNTs, inflammatory responses were more strongly induced in longer groups, whereas body weights more clearly decreased in shorter groups. SWCNT significantly decreased the relative weights of brain and kidney, and the inflow of immune cells and the hematological changes were observed significantly on day 1 and day 7 after exposure, respectively. Our results showed that the length and wall number of CNTs can serve as critical factors in the exhibited inflammation and toxicity.
Keywords
Carbon nanotube; Inflammation; Manufactured nanomaterials; Toxicity;
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Times Cited By KSCI : 1  (Citation Analysis)
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