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http://dx.doi.org/10.13065/jksdh.20220046

Analysis of oral pathogenic microorganisms in Alzheimer's dementia patients using nursing facilities  

Jung, Seo-Yun (Department of Oral Biochemistry, Chosun Dental University)
Jeong, Mi-Ae (Department of Dental Hygiene, Kangwon National University)
Kim, Chun-Sung (Department of Oral Biochemistry, Chosun Dental University)
Kim, Su-Gwan (Department of Oral Surgery, Sangmusu Dental Clinic)
Publication Information
Journal of Korean society of Dental Hygiene / v.22, no.5, 2022 , pp. 411-416 More about this Journal
Abstract
Objectives: This study aimed to identify pathogenic microorganisms in the oral cavity of Alzheimer's dementia patients and recognize the necessity and importance of oral prevention management. Methods: The participants comprised 40 dementia patients aged 60 years or older and general patients who were using nursing care facilities in Gwangju from February to July 2017. Samples were collected with Eazyperio products for oral pathogenic microbial testing. Eighteen types of bacteria could be detected by analyzing Multiplex-Quantity Real Time polymerase chain reaction at a genetic testing agency. Results: The study comprised more women than men. Most participants were in their 80s. Statistically significant differences were observed in some oral pathogenic microorganisms. Conclusions: Pathogenic microorganisms could more easily proliferate in the oral cavities of Alzheimer's dementia patients than they could among general elderly participants due to a lack of awareness of oral hygiene and prevention management. To improve this, it is considered necessary to deploy oral health care professionals.
Keywords
Alzheimer; Cognitive impairment; Degenerative neurological disease; Dementia; Pathogenic microorganisms;
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